Contents

The Italian Journal of Medicine (ITJM) is the official journal of FADOI, the Federation of Associations of Hospital Doctors on Internal Medicine and focus to describe the complex and variable situations confronted by Internists in daily practice. ITJM aims to promote excellence in the practice of internal medicine in hospitals and to disseminate the results of clinical research in internal medicine departments. The journal also contributes to the updating of hospital internists on general topics concerning public health, including ethical, legal, economical and health policy issues. The Journal includes original clinical research papers, reviews, case reports and specific sections dedicated to clinical pharmacology, chronic diseases, health management. ITJM is currently indexed in Web of Science/ESCI, Scopus and DOAJ since September 2009.

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• Prospective observational studies in clinical research: pros and cons

  Luca Bertolaccini, Matteo Nicoletto, Paola Piccolo, Fulvio Pomero

  https://doi.org/10.4081/itjm.2026.2600

  70

  Downloads: 46

• Operationalizing the Sixth Link: a systematic review of nurse-led interventions to mitigate psychological distress in lay rescuers

  Svetlana Mercuriali, Manuel Monti

  https://doi.org/10.4081/itjm.2026.2541

  184

  Downloads: 78

• Systemic Immune-Inflammation Index as an independent predictor of in-hospital morbidity in diabetic patients with ST-elevation myocardial infarction

  Rafid B. Altaweel, Abdulameer A. Abdulhameed, Karzan M. Abdullah

  https://doi.org/10.4081/itjm.2026.2563

  117

  Downloads: 74

• Reproducibility and inter-observer variability of the internal jugular vein ultrasonographic assessment: a multicenter cross-sectional study

  Nicola Parenti, Elena Guidetti, Davide Allegri, Anna Lombardi, Rita Verdoliva, Paolo Vita, Ripalta Amato, Pasqualino Sirignano, Mauro Silingardi, Paolo Caraceni, Roberta Esposito, Francesco Bellanti, Alberto Maria Marra, Daniele Caggianiello, Carmine Savoia

  https://doi.org/10.4081/itjm.2026.2547

  161

  Downloads: 80

• Prevention of sudden cardiac death in athletes: balancing safety, sustainability, and access to cardiovascular screening

  Pasquale Palmiero, Francesco Barone, Giuliana Laus, Loredana Latartara, Gabriella Chionna

  https://doi.org/10.4081/itjm.2026.2452

  213

  Downloads: 98

• Cluster-based epidemiological assessment in patients admitted to internal medicine with at least one of the following diagnoses: heart failure, chronic obstructive pulmonary disease or renal failure. The InCLuDimi study

  Ombretta Para, Flavio Tangianu, Nicola Tarquinio, Francesco Dentali

  https://doi.org/10.4081/itjm.2026.2498

  127

  Downloads: 92

• Analysis of factors associated with comprehensive knowledge about HIV/AIDS transmission and prevention among people aged 15-49 years in Eswatini: evidence from the 2021-2022 multiple indicator cluster survey

  Ahmed Sulaiman, Abdelrahman Abukanna, Hafiz Almisbah, Haider Elmisbah, Kamal Hamad, Zakariya Mohammed, Sanaa Mohammed

  https://doi.org/10.4081/itjm.2026.2490

  125

  Downloads: 112

• The hospitalist and co-management in multimorbid medical and surgical patients: a position paper from the EFIM multimorbidity working group

  Ombretta Para, Flora Kisuule, Arántzazu Álvarez-de Arcaya, Antonio Gonzalez Fernandez, Francisco J Rodríguez Gómez, Annette Kurrle, Maximo Bernabeu-Wittel

  https://doi.org/10.4081/itjm.2026.2511

  171

  Downloads: 138

• Organization of medical services for the Winter Olympic Games: the Milano-Cortina 2026 case

  Davide Croce, Giuseppe Massazza, Fabio Pigozzi, Diana Bianchedi, Thomas Toso

  https://doi.org/10.4081/itjm.2026.2496

  2227

  Downloads: 462

  HTML: 2

• Gender disparities in career among internal medicine physicians: evidence from a national survey of members of FADOI

  Elena Barbagelata, Roberto Scondotto, Silvia Calderone, Cecilia Politi, Giuseppa Triolo

  https://doi.org/10.4081/itjm.2026.2493

  1684

  Downloads: 565

  HTML: 18

• Anti-LGI1 autoimmune encephalitis mimicking rapidly progressive dementia in an elderly patient: a case report and review of the literature

  Carmine Siniscalchi, Nicoletta Cerundolo, Giuseppa Jolanda Rosa, Natasa Mojovic, Beatrice Prati, Tiziana Meschi

  https://doi.org/10.4081/itjm.2026.2483

  873

  Downloads: 361

  HTML: 103

• Chronic heart failure in an internal medicine outpatient setting: a retrospective real-world observational study of 30-day readmission and all-cause mortality

  Ettore Napoli, Laura Schiavon, Stefano Cuppini, Alberto Mazza

  https://doi.org/10.4081/itjm.2026.2517

  1365

  Downloads: 381

  HTML: 116

• Lipoid pneumonia: a narrative review of recent developments

  Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Loredana Di Nuzzo, Michela Carfora, Luigi Coppola, Maria Cerrone, Teresa Argenziano, Alessia Argenziano, Andrea Diglio, Angela Faggian

  https://doi.org/10.4081/itjm.2026.2499

  1717

  Downloads: 460

  HTML: 121

• Efficacy of compression stockings on preventing post-thrombotic syndrome: a systematic review and meta-analysis of randomized controlled trials

  Mosaad Almegren

  https://doi.org/10.4081/itjm.2026.2463

  2092

  Downloads: 660

  HTML: 116

• Correlation between obstructive sleep apnea syndrome and cardiovascular risk factors: a primary care strategy for early identification

  Manuel Monti, Maria Rosaria Manfredelli

  https://doi.org/10.4081/itjm.2026.2480

  984

  Downloads: 440

  HTML: 0

• Quantifying treatment effect: relative and absolute measures in clinical research

  Alberto Maino, Lorenza Bertù, Alessandro Squizzato, Paola Piccolo, Fulvio Pomero

  https://doi.org/10.4081/itjm.2026.2386

  772

  Downloads: 594

  HTML: 132

• Salivary creatinine is a promising noninvasive biomarker for chronic kidney disease: a case-control study

  Rabie Elagib Abdallah, Asma Anwar Mohammed, Afraa Ahmed Mohammed, Hala Mohammed Osman, Reel Nile Awad Elkareem, Hiba Mahgoub Ali Osman, Imadeldin Elfaki, Majdolin Mohammed Eltayeb Elsiddig, GadAllah Modawe

  https://doi.org/10.4081/itjm.2026.2419

  1316

  Downloads: 511

  HTML: 189

• Orthostatic hypotension in hospitalized hypertensive patients admitted to internal medicine wards: rationale and design of the HYP-OP Study

  Claudio Ferri, Dario Manfellotto, Alberto Mazza, Francesco Dentali, Maria D’Avino, Antonella Valerio, Grzegorz Bilo, Gianfranco Parati, Andrea Fontanella, FADOI HYP-OP Study Group

  https://doi.org/10.4081/itjm.2026.2494

  1004

  Downloads: 479

  HTML: 1

• FADOI official position on artificial intelligence in internal medicine

  Daniela Tirotta, Fabio Di Bello, Francesco Dentali, Dario Manfellotto, Paola Gnerre, Andrea Montagnani

  https://doi.org/10.4081/itjm.2026.2482

  1463

  Downloads: 731

  HTML: 118

• Influence of L-citrulline supplementation along with conventional treatment and its effect on inflammatory markers in patients with non-alcoholic fatty liver disease

  Zergham Mazhar, Sana Farooq, Misbah Arshad, Sidra Khalid, Humaira Waseem, Shaista Jabeen, Siti Sarah Maidin, Adnan Essam Abukhashabah, Dahlia Mirdad, Mohammed Matoog Karami, Ali A Mousa

  https://doi.org/10.4081/itjm.2026.2113

  1482

  Downloads: 394

  HTML: 0

• Integrating WHO-HAEM5 classification, 18F-FDG PET/CT imaging, and molecular profiling in lymphoma management: implications for prognosis, follow-up, and personalized therapy (2020-2025 systematic review)

  Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Andrea Diglio, Angela Faggian

  https://doi.org/10.4081/itjm.2026.2406

  453

  Downloads: 346

  HTML: 1

• Fatal transfusion-related acute lung injury type II following red blood cell transfusion in a cancer patient with suspected endocarditis: a case report

  Paolo Tirelli, Gianluigi Cuomo, Domenico Birra, Claudio De Luca, Antonietta De Sena, Fabio Granato Corigliano, Mariavittoria Guerra, Carmine Fierarossa, Benedetta Tartaglia, Vittoria Gammaldi, Carolina Bologna, Gabriella Oliva, Pasquale Madonna, Vincenzo Nuzzo

  https://doi.org/10.4081/itjm.2026.2407

  662

  Downloads: 400

  HTML: 19

• The research question: a first, essential step in study design

  Aldo Bonaventura, Roberta Buso, Francesco Dentali

  https://doi.org/10.4081/itjm.2026.2130

  359

  Downloads: 542

  HTML: 23

• The health of migrants: the doctor-patient relationship

  Giuseppa Triolo, Valeria Pignatelli, Anna Vigilante, Cecilia Politi

  https://doi.org/10.4081/itjm.2026.2411

  293

  Downloads: 281

  HTML: 0

• Standardized emergency department protocol for non-traumatic chest pain: experience from the USL Umbria 1 Health Authority

  Manuel Monti, Giovanni Dorilli, Laura Gasperini, Michele Marvardi

  https://doi.org/10.4081/itjm.2026.2377

  598

  Downloads: 531

  HTML: 0

• Acute epiploic appendagitis: a case report and literature review

  Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Andrea Diglio, Angela Faggian

  https://doi.org/10.4081/itjm.2026.2384

  371

  Downloads: 316

  HTML: 20

• Unveiling silent threats: incidental diagnosis and conservative management of spontaneous isolated celiac artery dissection

  Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Andrea Diglio, Angela Faggian

  https://doi.org/10.4081/itjm.2026.2385

  485

  Downloads: 363

  HTML: 22

• Liver Imaging Reporting and Data System: current status and future perspectives in the diagnosis of hepatocellular carcinoma

  Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Alessia Argenziano, Andrea Diglio, Angela Faggian

  https://doi.org/10.4081/itjm.2026.2413

  910

  Downloads: 354

  HTML: 0

• The evolving role of selective internal radiation therapy in hepatocellular carcinoma

  Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Alessia Argenziano, Andrea Diglio, Angela Faggian

  https://doi.org/10.4081/itjm.2026.2414

  737

  Downloads: 438

  HTML: 0

• Le implicazioni medico-legali della pratica clinica dell’internista

  Elisabetta Romboli

  https://doi.org/10.4081/itjm.q.2025.5

  459

  Downloads: 506

• The hidden toll of war: long-term health risks at Europe’s doorstep

  Carmine Siniscalchi, Egidio Imbalzano, Pierpaolo Di Micco

  https://doi.org/10.4081/itjm.2025.2403

  284

  Downloads: 257

  HTML: 0

• Relationship of adiponectin levels with the severity of chronic obstructive pulmonary disease

  Rismawaty Samonding, Muh Ilyas, Bulkis Natsir, Irawaty Djaharuddin, Sitti Nurisyah, Erwin Arief

  https://doi.org/10.4081/itjm.2025.2015

  364

  Downloads: 341

  HTML: 0

• Women’s leadership in the healthcare landscape. Original evidence from an innovative narrative review of the literature: the female-led study

  Filomena Pietrantonio, Giorgia Mochi, Lidia Ricci, Maria Sofia Simonelli, Lucilla Boschero, Biagio D'Alessandro, Francesca Bruno, Luisa Pieragostini, Emilia Migliano, Giovanna Russo, Gabriele Angelo Vassallo, Marco Materazzo, Giuseppa Granvillano, Antonio Vinci, Alessandro Signorini, Francesco Rosiello

  https://doi.org/10.4081/itjm.2025.2398

  658

  Downloads: 399

  HTML: 41

• Correlation of serum cardiolipin levels with physical activity in type 2 diabetes mellitus patients

  Ayesha Aslam, Shazia Bokhari, Riffat Mehboob, Uzma Rafi, Zeeshan Mehboob, Deema Sabtan, Mohammed M. Karami, Hani Sadaka Shalabi

  https://doi.org/10.4081/itjm.2025.2363

  296

  Downloads: 292

  HTML: 27

• Globalization, climate change, and the re-emergence of West Nile, Dengue, and Zika viruses

  Carmine Siniscalchi, Maria Gabriella Coppola, Giuseppe Cardillo, Egidio Imbalzano, Manuela Basaglia, Rodolfo Nasti, Vincenzo Russo, Pierpaolo Di Micco

  https://doi.org/10.4081/itjm.2025.2404

  581

  Downloads: 515

  HTML: 51

• How should we manage political instability in our standard of care? A global emerging issue around the world

  Pierpaolo Di Micco, Carmine Siniscalchi

  https://doi.org/10.4081/itjm.2025.2371

  270

  Downloads: 259

  HTML: 0

• Legionella infection with renal and muscular complications: a clinical case with a focus on clinical aspects and imaging diagnostics

  Guido Faggian, Roberto Faggian, Michela Salzano, Vincenza Galeone, Andrea Diglio, Angela Faggian

  https://doi.org/10.4081/itjm.2025.2088

  479

  Downloads: 348

  HTML: 67

• Costipazione indotta da oppioidi e raccomandazioni semplificate per la diagnosi e la gestione

  Filomena Panzone, Mauro Carbone, Gianlorenzo Imperiale

  https://doi.org/10.4081/itjm.q.2025.3

  348

  Downloads: 228

• Right ventricle migration of a peripherally inserted central catheter: case report and literature review

  Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Andrea Diglio, Angela Faggian

  https://doi.org/10.4081/itjm.2025.2123

  760

  Downloads: 361

  HTML: 89

• A rare disease causing carpal tunnel syndrome

  Paolo Agostinis, Michele Battellino

  https://doi.org/10.4081/itjm.2025.2137

  669

  Downloads: 439

  HTML: 36

• The clinical value of fibrinogen and thromboelastography in the predictive assessment of the progression of persistent postpartum hemorrhage

  Huicong Yin, Huili Fan, Wenjuan Ma

  https://doi.org/10.4081/itjm.2025.2109

  655

  Downloads: 560

  HTML: 53

• Continuity of care in acute coronary syndrome: why dedicated clinics for post-acute coronary syndrome management make the difference

  Maria Maiello, Francesco Proce, Cosima Caputo, Pasquale Palmiero

  https://doi.org/10.4081/itjm.2025.2054

  363

  Downloads: 384

  HTML: 54

• What does a fall to the ground hide? An atypical onset of follicular B-cell lymphoma

  Maurizio Renda, Silvia Scriffignano, Sabrina Mancuso, Silvana Leanza, Maurizio Musso, Valerio Alaimo

  https://doi.org/10.4081/itjm.2025.1869

  376

  Downloads: 336

  HTML: 30

• Yamaguchi syndrome: a rare type of hypertrophic cardiomyopathy

  Donart Zymberi, Muhamet Kadrija

  https://doi.org/10.4081/itjm.2025.2133

  781

  Downloads: 472

  HTML: 460

• The role of adiponectin in diabetic retinopathy and insulin resistance

  Shahad Kh. Hameed, Rawaa F. Jawad, Haidar Ahmad Shamran

  https://doi.org/10.4081/itjm.2025.2049

  461

  Downloads: 361

  HTML: 26

• The impact of diabetes on the outcomes of lower extremity arterial disease in patients with vascular surgical interventions in Kosovo

  Dion Haliti, Dea Haliti, Laura Leci Tahiri, Nora Shabani-Behrami, Elena Hajdari, Naim Haliti, Ragip Shabani, Fehim Haliti, Qenan Maxhuni, Rrahman Ferizi

  https://doi.org/10.4081/itjm.2025.2095

  647

  Downloads: 832

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• Cognitive impairment and associated metabolic and hormonal factors in women with polycystic ovarian syndrome: a Montreal Cognitive Assessment-based case-control study

  Muhanad Mahdi Dhumad, Farqad Bader Hamdan, Qasim Sharhan Al-Mayah

  https://doi.org/10.4081/itjm.2025.2085

  1034

  Downloads: 554

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• The relationship between vitamin D levels and clinical symptoms and lesion size in chest radiographs of pulmonary tuberculosis in patients with comorbid diabetes mellitus

  Andi Nurrahma Ramli, Erwin Arief, Sitti Nurisyah, Jamaluddin Maddolangan, Harry Akza Putrawan, Nur Ahmad Tabri

  https://doi.org/10.4081/itjm.2025.2053

  539

  Downloads: 468

  HTML: 44

• Epidemiological trends and determinants of hypertensive disorders in pregnancy: a 10-year retrospective study

  Desard Hashorva, Eva Muja, Eduart Hashorva

  https://doi.org/10.4081/itjm.2025.2131

  552

  Downloads: 344

  HTML: 26

• The role of bronchial washing of transforming growth factor β1 as a prognostic biomarker of advanced stages of non-small cell lung cancer

  Nur Afifah Thamrin, Arif Santoso, Sitti Nurisyah, Irawaty Djaharuddin, Harun Iskandar

  https://doi.org/10.4081/itjm.2025.2065

  850

  Downloads: 507

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• Exploring some pro-inflammatory cytokines and adipokines as novel biomarkers in polycystic ovary syndrome

  Dlvin Akif Mustafa, Parween Abdulsamad Ismail

  https://doi.org/10.4081/itjm.2025.2023

  1114

  Downloads: 647

  HTML: 72

• Determinants of hepatitis B vaccination coverage in children aged 12-23 months: evidence from the Multiple Indicator Cluster Survey

  Husham O. Elzein, Elryah I. Ali, Mohammed Suleiman Zaroog, Eltigani O.M. Omer, Kamal Elbssir Mohammed Ali, Eltayeb I.O. Elmahi, Sara H.M. Hamad, Zakariya M.S. Mohammed

  https://doi.org/10.4081/itjm.2025.1976

  420

  Downloads: 486

  HTML: 37

• A case of acute psychotic episode at the onset of primary aldosteronism

  Davide Cunzi, Maria Giulia Canè, Giorgia Prampolini, Silvia Umbertina Fedeli, Aurelio Negro

  https://doi.org/10.4081/itjm.2025.2052

  406

  Downloads: 381

  HTML: 107

• Maximizing the success of percutaneous nephrolithotomy under spinal anesthesia by postoperative bleeding and fever prediction using demographic and intraoperative risk factors

  Muhammad Yasin Chaudhry, Muhammad Rizwan Farooqi, Asad Munir, Umaima Jalil, Razia Parveen Chaudhry, Andleeb Tariq, Rabia Noor, Umair Ahmed, Arbaz Munir

  https://doi.org/10.4081/itjm.2025.2035

  642

  Downloads: 432

  HTML: 182

• Assessing tumor necrosis factor-α (-238 G/A and -308 G/A) genetic polymorphisms in sepsis susceptibility among cystic fibrosis patients

  Qahtan A. Mahdi, Jabbar S. Hassan, Abdulrhman M. Hassan Hadi, Ali Nayyef Umayra

  https://doi.org/10.4081/itjm.2025.2021

  551

  Downloads: 381

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• The impact of tocilizumab on hepatic enzyme levels in rheumatoid arthritis patients: a narrative review

  Rrezarta Alihajdaraj, Ergeta Ktona, Blerta Budani, Jehona Ismaili Kadriaj

  https://doi.org/10.4081/itjm.2025.2000

  1673

  Downloads: 621

  HTML: 57

• Internal-surgical co-management in emergency surgery: proposal of an organizational model

  Ombretta Para, Matteo Tomaiuolo, Asim Raza, Christian Carleo, Lucia Lipari, Alessio Giordano, Giovanni Alemanno, Paolo Prosperi, Carlo Nozzoli

  https://doi.org/10.4081/itjm.2025.1886

  669

  Downloads: 724

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• Analysis of the risk factors of hepatitis on the rate of recovery in pulmonary tuberculosis patients

  Muh Ridho Akbar, Irawaty Djaharuddin, Edward Pandu Wiriansya, Jamaluddin Madolangan, Harun Iskandar, Harry Akza Putrawan

  https://doi.org/10.4081/itjm.2025.2064

  757

  Downloads: 504

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• The health of migrants

  Giuseppa Triolo, Cecilia Politi, Valeria Pignatelli

  https://doi.org/10.4081/itjm.2025.1994

  361

  Downloads: 490

  HTML: 63

• Primary aldosteronism unmasked during pregnancy: a case report

  Antonio Concistrè, Claudia Caramazza, Marco D’Abbondanza, Giuseppe Imperoli

  https://doi.org/10.4081/itjm.2025.1949

  705

  Downloads: 439

  HTML: 97

• Challenges and evolution of the Italian National Health Service: between crisis and reform

  Pierpaolo Di Micco, Egidio Imbalzano, Carmine Siniscalchi

  https://doi.org/10.4081/itjm.2025.2100

  596

  Downloads: 903

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• The effect of type 2 diabetes mellitus on clinical symptoms, sputum molecular test results, and lesions in thoracic photos of pulmonary tuberculosis patients

  Fikriatul Fadhilah, Erwin Arief, Nur Ahmad Tabri, Irawaty Djaharuddin, Arif Santoso, Jamaluddin Madolangan

  https://doi.org/10.4081/itjm.2025.2048

  1209

  Downloads: 453

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• Role of sodium-glucose cotransporter 2 inhibitors in cardiovascular events in patients with heart failure

  Eva Muja, Letizia Giuseppina Floccari, Artan Simaku, Klodeta Grosha, Besim Lama, Ilirian Laçi

  https://doi.org/10.4081/itjm.2025.1997

  778

  Downloads: 488

  HTML: 56

• Risk factors for colorectal cancer in Albania: a case-control study

  Marsela Sina, Skerdi Prifti, Adea Kocollari, Ilir Akshija, Dorina Osmanaj, Gentiana Qirjako

  https://doi.org/10.4081/itjm.2025.2007

  742

  Downloads: 493

  HTML: 47

• The parental challenge: knowledge, attitudes, and practices on iron deficiency anemia in Tabuk

  Sawsan Mohammed Alblewi, Amerah M Alatawi, Faisal Mayudh Althobaiti, Adel Ali Alharfi, Faisal Mohammed Alamrani, Yazeed Mahmoud Ajwah, Omar Muslih Albalawi, Mohammed Majed Alquayr, Ariam Ebraheem Alshammari

  https://doi.org/10.4081/itjm.2025.1946

  1331

  Downloads: 787

  HTML: 243

• Utility of the aspirin and P2Y12 response assays to determine the effects of antiplatelet agents in patients with subdural hematoma undergoing neurosurgery

  Ombretta Para, Christian Carleo, Francesco Bucci, Lucia Lipari, Asim Raza, Edoardo Cesaroni, Chiara La Rovere, Simone Orlandini, Gastone Pansini, Alberto Parenti, Giovanni Muscas, Alessandro Della Puppa

  https://doi.org/10.4081/itjm.2025.1926

  958

  Downloads: 941

  HTML: 0

• Perceived stress in parents of children with neurodevelopmental disorders: psychometric properties of the stress measurement scale in the Moroccan dialect

  Sara Alouane, Zakaria Abidli, Ahmed O.T. Ahami, Soukaina El Idrissi, Jamila Riyahi

  https://doi.org/10.4081/itjm.2025.1991

  743

  Downloads: 493

  HTML: 87

• Age diversity management in healthcare: leveraging generational differences with an inclusive approach

  Filomena Pietrantonio, Giulia Brunelli, Gabriele Angelo Vassallo, Luca Moriconi, Alessandro Signorini, Andrea Moriconi

  https://doi.org/10.4081/itjm.2025.2074

  1960

  Downloads: 1390

  HTML: 323

• Differential diagnosis of prion diseases in the vast chapter of degenerative encephalopathies, a challenge for the internist: two case reports compared

  Filomena Pietrantonio, Angela Ciamei, Gabriele Angelo Vassallo, Luca Moriconi, Margherita Lordi

  https://doi.org/10.4081/itjm.2025.2075

  633

  Downloads: 468

  HTML: 79

• The future of diagnostics: cutting-edge advances in healthcare technology

  Ashok Kumar Sah, Darla Srinivasa Rao, Anass M Abbas, M Chandrasekar, Mohamed Ahmed Mohamed Adam, Ajab Singh Choudhary, Ranjay Kumar Choudhary, Rabab H. Elshaikh, Pranav Kumar Prabhakar, Syrsulu Myrzagulova, Rohit Rathore, Asaad M. Babker, Devendra Prasad, Shagun Agarwal

  https://doi.org/10.4081/itjm.2025.1932

  1347

  Downloads: 667

  HTML: 711

• Association between 25-hydroxy vitamin D insufficiency and serum uric acid levels compared to the gender and age categories

  Salah Eldin Omar Hussein, Awadh S. Alsubhi, Abdulrahman Algarni, Elryah I. Ali, Tagwa Yousif Elsayed Yousif, Ammar Abdelmola, Elyasa Elfaki, Wael Alzahrani, Ayman Hussien Alfeel

  https://doi.org/10.4081/itjm.2025.2029

  1661

  Downloads: 462

  HTML: 50

• A case report of bladder cancer-related acquired hemophilia A

  Gaia Dragoni, Nicolò Ferraroni, Raffaella Benedetti, Aderville Cabassi, Davide Imberti

  https://doi.org/10.4081/itjm.2025.2019

  679

  Downloads: 476

  HTML: 65

• Correlation of circulating diabetes markers with elevated serum antithyroglobulin antibodies in type 2 diabetes patients

  Batool Ibrahim Aljasmmi, Awadh S Alsubhi, Abdulrahman Algarni, Elryah I Ali, Ammar Abdelmola, Hussam Ali Osman, Abdelrahman Mohamed Ahmed Abukanna, Marwan Ismail, Asaad Babker, Salah Eldin Omar Hussein

  https://doi.org/10.4081/itjm.2025.1961

  955

  Downloads: 533

  HTML: 63

• Minimally invasive versus median sternotomy for mechanical mitral valve replacement: a single-center comparative study of treatment outcomes and quality of life

  The Binh Nguyen, Tran-Thuy Nguyen, Long Hoang Luong, Duc Hoang Nguyen, Cong Huu Nguyen, Ngoc Thanh Le, Bao Giang Kim

  https://doi.org/10.4081/itjm.2025.1963

  3330

  Downloads: 628

  HTML: 0

• The role of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in assessing hypothyroidism Hashimoto’s thyroiditis

  Ruqeya Murad, Ayman H. Alfeel, Zulekha Shemote, Praveen Kumar, Asaad Babker, Ahmed Luay Osman, Abdelgdair A. Altoum

  https://doi.org/10.4081/itjm.2025.1953

  1601

  Downloads: 691

  HTML: 220

• Gender differences and post-pandemic mental health impacts: a mediation study on Vietnamese adolescents

  Thanh Long Nguyen, Victor Storm, Lam Toi Phung, Cong Thien Le, Thi Thu Ha Le, Thi Hoa Nguyen, Son Tung Vu, Thien Thang Tran, Minh Hanh Vu, Van Tuan Nguyen

  https://doi.org/10.4081/itjm.2025.1888

  1575

  Downloads: 1117

  HTML: 40

• Intermediate care units in internal medicine: the case of Apulia

  Francesco Ventrella, Anna Belfiore, Antonio Greco, Franco Mastroianni, Salvatore Lenti, Domenico Ruggiero, Michele Cannone, Vincenzo Ostilio Palmieri, Massimo Errico

  https://doi.org/10.4081/itjm.2025.1960

  1259

  Downloads: 600

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• Peritoneal involvement in acute pericarditis with polyserositis may mimic acute cholecystitis: a case report

  Emanuele Bizzi, Francesco Moda, Massimo Pancrazi, Alice Pedroli, Ruggiero Mascolo, Antonio Luca Brucato

  https://doi.org/10.4081/itjm.2025.1931

  836

  Downloads: 592

  HTML: 81

• A “cold” case of myxedema coma

  Elisa Eletto, Carmine Siniscalchi, Nicoletta Cerundolo, Beatrice Prati, Lorenzo Finardi, Riccardo Simoni, Alberto Parise, Antonio Nouvenne, Tiziana Meschi

  https://doi.org/10.4081/itjm.2025.1999

  1268

  Downloads: 731

  HTML: 0

• Impact of tumor necrosis factor-α and interleukin 6 polymorphisms on type 2 diabetes mellitus Sudanese patients

  Elmutuz H. Elssaig, Abdalla Eltoum Ali, Mohammed A. Alsubai, Tarig M.S. Alnour, Eltayib H. Ahmed-Abakur, Aadil Yousif, Bashayr Mudhhi Alshehri, Fatmah Ali Awaji, Arwa Murdi Alanazi, Fai Fahad Alanazi, Abdullah Ali Alghamdi

  https://doi.org/10.4081/itjm.2025.1967

  1159

  Downloads: 538

  HTML: 0

• Pulmonary nodules in rheumatoid arthritis: the case of leflunomide

  Giovanni Simone Mancini, Silvia Rampini, Stefania Freguia, Clara Valsecchi, Domenico Cozzo, Anna Lou Christe, Adam Ogna

  https://doi.org/10.4081/itjm.2025.1964

  1313

  Downloads: 451

  HTML: 108

• First-level clinical point-of-care ultrasound: an essential tool for today’s internist

  Mauro Silingardi, Nicola Mumoli, Emanuela Laurita, Elisa Romagnoli, Giovanna Casoli, Stefania Marengo, Federica Agrusta, Marinella Tricarico, Luisa Arnaldi, Giovanni Gardini, Francesco Dentali

  https://doi.org/10.4081/itjm.2025.1939

  838

  Downloads: 525

  HTML: 43

• Employing the European Thyroid Imaging Reporting and Data System 2017 classification in a malignancy risk stratification system for thyroid nodules at Can Tho Oncology Hospital from 2021 to 2023

  Vo Van Kha, Tran Thi Huong Ly, Pham Thi Thanh Hoa, Vo Huynh Nhu

  https://doi.org/10.4081/itjm.2025.1852

  2035

  Downloads: 845

  HTML: 83

• Metformin’s therapeutic potential in adenomyosis: insights from interleukin 8 level

  Damas Hendriansyah, Nusratuddin Abdullah, Rudy B. Leonardy, Mardiah Tahir, Samrichard Rambulangi, Firdaus Hamid

  https://doi.org/10.4081/itjm.2025.1940

  2615

  Downloads: 1330

  HTML: 0

• An innovative model of university cooperation in developing countries: results of five years of experience in internal medicine, health promotion and education

  Filomena Pietrantonio, Vera Kopsaj, Francesco Rosiello, Aurora Tomassoni, Luca Moriconi, Donatella Padua

  https://doi.org/10.4081/itjm.2025.1941

  1144

  Downloads: 543

  HTML: 36

• When should antihypertensive drug treatment be started? Discrepancies between the 2023 European Society of Hypertension and the 2024 European Society of Cardiology guidelines

  Giuseppe Mancia, Guido Grassi, Sverre E. Kjeldsen

  https://doi.org/10.4081/itjm.2025.1981

  1983

  Downloads: 818

  HTML: 0

• Correlation between neutrophil-to-lymphocyte ratio and soluble FMS-like tyrosine kinase 1 in pregnant women with preeclampsia

  Kiki Rizki Amelia, Efendi Lukas, Nurbani Bangsawan, Isharyah Sunarno, Retno Budiarti Farid, Sriwijaya Qadar

  https://doi.org/10.4081/itjm.2025.1924

  863

  Downloads: 507

  HTML: 38

• Mentzer Index and Red Cell Distribution Width Index in differentiating iron deficiency anemia and β-thalassemia trait

  Rabab H. Elshaikh, Ashok Kumar Sah, Abdelrahman Mohamed Abukanna, Abdulrahman Algarni, Ammar Abdelmola, Hussam Ali Osman, Tagwa Yousif Elsayed Yousif, Elryah I. Ali, Hiba Ali, Ayman Hussein Alfeel

  https://doi.org/10.4081/itjm.2025.1892

  5189

  Downloads: 1307

  HTML: 0

• Cytokine profile in COVID-19 infection: focus on interleukin-13, interleukin-33, and tumor necrosis factor-α as immunological markers

  Huda Saleem, Wafaa Hazim, Batool Mutar Mahdi, Mohammed S. Al-Iedani

  https://doi.org/10.4081/itjm.2025.1823

  1186

  Downloads: 816

  HTML: 109

• The role of genetic variations in metabolic syndrome: insights into etiology, diagnosis, and management

  Darla Srinivasa Rao, Ajay Kumar, Shagun Agarwal, Rabab Hassan Elshaikh, AjabSingh Choudhary, Ranjay Kumar Choudhary, Assad M A Babker, Rohit Rathore, Zhannat Nurmakhanova, Zhanar Nurgaliyeva, Abdugani Musayev, Ashok Kumar Sah

  https://doi.org/10.4081/itjm.2025.1908

  1892

  Downloads: 896

  HTML: 89

• The man from the stars: a narrative approach to neglected diseases

  Paolo Agostinis, Teresa Michelutti, Laura Iogna Prat, Omar Simonetti

  https://doi.org/10.4081/itjm.2025.1900

  869

  Downloads: 564

  HTML: 103

• Embracing artificial intelligence in internal medicine: a tool for physicians and patients

  Matteo Giorgi-Pierfranceschi

  https://doi.org/10.4081/itjm.2025.1791

  856

  Downloads: 573

  HTML: 4

• Immunohistochemical expression of transient receptor potential vanilloid 1 in World Health Organization grade IV astrocytoma, oral squamous cell carcinoma and bladder carcinoma

  Imrana Tanvir, Samina Qamar, Ahmad Alwazzan, Khurram Mehboob, Yousef Almehmadi, Ebtihal Ali Alharbi, Shadi Ahmed Alahmadi, Hafsa Adnan

  https://doi.org/10.4081/itjm.2025.1893

  953

  Downloads: 652

  HTML: 121

• Effect of magnesium and potassium on rheumatoid arthritis factor and quality of life in patients with type 2 diabetes mellitus: a randomized control trial

  Hafiza Sonia Bibi, Uzma Rafi, Sidra Khalid, Riffat Mehboob, Anbreen Bibi, Hani Sadaka Shalabi, Mohammed A. Zaher, Samy A. Abusikkien

  https://doi.org/10.4081/itjm.2025.1874

  2039

  Downloads: 878

  HTML: 94

• La sindrome cardio-nefro-metabolica

  Andrea Montagnani, Dario Manfellotto

  1-38

  https://doi.org/10.4081/itjm.q.2025.1

  1440

  Downloads: 1352

• Diagnostic and therapeutic care pathway of the Cardiac Network for Heart Failure

  Pasquale Palmiero, Matteo Durante, Maria Maiello, Valentina D’Andria, Cosima Caputo, Lucia Giordano

  https://doi.org/10.4081/itjm.2025.1927

  1157

  Downloads: 589

  HTML: 104

• A toothpick man user with COVID-19

  Francesco Serafini, Elia Vettore, Fabio Presotto

  https://doi.org/10.4081/itjm.2025.1897

  794

  Downloads: 498

  HTML: 84

• Visceral leishmaniasis and lymphoma: a rare and dangerous couple

  Nicola Battino, Antonio Pisano

  https://doi.org/10.4081/itjm.2025.1843

  882

  Downloads: 596

  HTML: 1

• CO-St (COVID 19-study): sex differences in the treatment of COVID-19

  Manuel Monti, Tiziana Ciarambino, Filomena Pietrantonio, Sara Rotunno, Alessandra Fiorentini, Rosalba Cipriani, Giuseppe Campagna, Giuseppe Straface, Eleonora Pistella, Mauro Giordano, Orazio Valerio Giannico, Roberto Marchetti, Federica Lorenzi, Francesco Rosiello

  https://doi.org/10.4081/itjm.2025.1916

  1142

  Downloads: 564

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• Evaluation of the renal function among sickle cell patients: a cross-sectional study

  Talal Qadah, Anwar Refaei

  https://doi.org/10.4081/itjm.2025.1868

  829

  Downloads: 1020

  HTML: 76