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The Italian Journal of Medicine (ITJM) is the official journal of FADOI, the Federation of Associations of Hospital Doctors on Internal Medicine and focus to describe the complex and variable situations confronted by Internists in daily practice. ITJM aims to promote excellence in the practice of internal medicine in hospitals and to disseminate the results of clinical research in internal medicine departments. The journal also contributes to the updating of hospital internists on general topics concerning public health, including ethical, legal, economical and health policy issues. The Journal includes original clinical research papers, reviews, case reports and specific sections dedicated to clinical pharmacology, chronic diseases, health management. ITJM is currently indexed in Web of Science/ESCI, Scopus and DOAJ since September 2009.

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New Articles

• The incidence of bleeding in patients with nonvalvular atrial fibrillation using anticoagulants: a real-world report with the biggest Vietnamese data

  Bui The Dung, Cao Ngoc Mai Han, Tran Hoa, Nguyen Thanh Hien

  https://doi.org/10.4081/itjm.2025.1807

  2411

  PDF: 574

  HTML: 1

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• An algorithm for the management of chronic obstructive pulmonary disease patients in units of internal medicine

  Ombretta Para, Carmen Stabile, Donato Cinquepalmi, Maria Sandra Magnoni, Francesco Nasso, Flavio Tangianu, Mauro Silingardi, Antonella Valerio, Dario Manfellotto, Francesco Dentali

  https://doi.org/10.4081/itjm.2025.1838

  2112

  PDF: 1838

  HTML: 149

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• The unseen connection: laryngeal carcinoma and thrombosis of the internal jugular vein

  Laura Leci-Tahiri, Lisa Tahiri, Valbona Zhjeqi, Emina Ramku

  https://doi.org/10.4081/itjm.2025.1882

  2216

  PDF: 494

  HTML: 209

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• Predictive value of Frank’s sign for obstructive coronary artery disease confirmed by coronary computed tomography angiography

  Truong Phi Hung, Nguyen Minh Kha, Dang Tuong Vi, Tran Trong Nhan, Hoang Van Sy

  https://doi.org/10.4081/itjm.2025.1863

  5423

  PDF: 704

  SUPPLEMENTARY MATERIAL: 268

  HTML: 526

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• Right ventricular failure due to subacute massive pulmonary embolism

  Claudio Giumelli, Giacomo Bussolati, Patricia Granauro, Paolo Montanari

  https://doi.org/10.4081/itjm.2025.1747

  1791

  PDF: 478

  VIDEO 1: 312

  HTML: 99

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• First evidence of immunomodulation of the renin-angiotensin system through substance P/neurokinin 1 receptor: a case and control study in hypertension and cardiac patients

  Ibrahim M. Alanazi, Riffat Mehboob, Ayesha Tariq, Sajid Hameed, Uzma Malik, Noreen Sarwar, Imran Shahid, Khurram Mehboob

  https://doi.org/10.4081/itjm.2025.1870

  1585

  PDF: 819

  HTML: 82

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• Maternal, fetal, and perinatal outcomes of COVID-19-infected pregnancies in Saudi Arabia: a meta-analysis and systematic review

  Ahmad Alwazzan

  https://doi.org/10.4081/itjm.2025.1877

  1499

  PDF: 787

  HTML: 89

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• Exploring the determinants of exclusive breastfeeding among postpartum women in northeastern Morocco: fathers’ knowledge as a moderating factor

  Khalid Faraj, Abdellatif Bour

  https://doi.org/10.4081/itjm.2025.1861

  1410

  PDF: 879

  HTML: 3

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• Early and late outcomes of emergency coronary bypass grafting in non-ST-segment elevation acute myocardial infarction

  Nguyen Thai Minh, Nguyen Sinh Hien, Bui The Dung, Doan Quoc Hung

  https://doi.org/10.4081/itjm.2025.1808

  1420

  PDF: 795

  HTML: 290

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• C-reactive protein as a diagnostic marker for ovarian carcinoma

  Angga Dewi Umar Wahyu, Syahrul Rauf, Susiawaty Susiawaty, Maisuri T. Chalid, Nugraha Utama Pelupessy, Irma Savitri

  https://doi.org/10.4081/itjm.2025.1819

  2297

  PDF: 642

  HTML: 27

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• Role of platelet indices and vitamin D in forecasting deterioration of glycemic control and vascular complications in type 2 diabetes

  Maryam Ahmed Obaid Al Ali, Khalid Abdelsamea Mohamedahmed, Asaad Ma Babker

  https://doi.org/10.4081/itjm.2025.1875

  1397

  PDF: 773

  HTML: 26

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• Skin lesions and the role of the internist: a series of clinical cases

  Carolina Bologna, Domenico Birra, Marina Lugarà, Antonietta De Sena, Gabriella Oliva, Paolo Tirelli, Pasquale Madonna, Vincenzo Nuzzo

  https://doi.org/10.4081/itjm.2024.1796

  1511

  PDF: 514

  HTML: 43

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• Stochastic Petri net model with random time of Vietnamese ischemic stroke patient treatment process

  Nguyen Tien Dung, Nguyen-Thi Phuong Quynh, Ho Cam Tu, Bui-Thi Thu Huong, Pham-Thi Thuy, Vu-Thi Hoai Thu, Lo Minh Trong, Ho Khanh Lam, Nguyen Phuong Sinh

  https://doi.org/10.4081/itjm.2024.1806

  1713

  PDF: 633

  HTML: 29

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• Profile of dietary supplement consumers in the region of Rabat-Salé-Kénitra, Morocco

  Oumaima Touijri, Btihaj Al Ibrahmi, Yassmine Nahab, Ali Quyou, Moulay Laarbi Ouahidi

  https://doi.org/10.4081/itjm.2024.1857

  1957

  PDF: 549

  HTML: 47

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• Obesity: a potential cause of varicocele leading to male infertility

  Zain ul Hasan, Syed Amir Gilani, Asif Hanif, Raham Bacha, Zareen Fatima

  https://doi.org/10.4081/itjm.2024.1827

  3048

  PDF: 493

  HTML: 63

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• Screening of the key genes and signaling pathways for schizophrenia using bioinformatics and next generation sequencing data analysis

  Iranna Kotturshetti, Basavaraj Vastrad, Veena Kori, Chanabasayya Vastrad, Shivakumar Kotrashetti

  https://doi.org/10.4081/itjm.2024.1830

  3642

  PDF: 722

  SUPPLEMENTARY MATERIAL: 266

  HTML: 15

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• Assessment of the knowledge of pregnant women with gestational diabetes regarding diet and physical activity in Morocco

  Hanane Azargui, Btihaj AL Ibrahmi, Abdellatif Bour

  https://doi.org/10.4081/itjm.2024.1849

  1705

  PDF: 527

  HTML: 46

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• Is a terminally ill non-cancer patient really forced to stay at the hospital?

  Francesco Serafini, Maria Gabriella Procacci, Elia Vettore, Giulia Cardinali, Fabio Presotto

  https://doi.org/10.4081/itjm.2024.1850

  1154

  HTML: 29

  PDF: 468

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• Retrieving the information stored in the donated organ may cause the patient’s personality to change after the transplant operation

  Jamal Al-Karaki, Muhammad Al-Zafar Khan, Phoka Rathebe, Raul Valverde, Alireza Sepehri, Massimo Fioranelli

  https://doi.org/10.4081/itjm.2024.1790

  1732

  PDF: 650

  HTML: 1106

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• La medicina perioperatoria e il co-management medico-chirurgico: position paper FADOI-ACOI In collaborazione con SISET, SIMIT, SIN, SINPE

  Davide Carrara, Francesco Dentali

  1-48

  https://doi.org/10.4081/itjm.q.2024.7

  1266

  PDF: 1785

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• The importance of the cardiology observation unit in the management of patients with cardiovascular diseases: a pilot project

  Manuel Monti, Simone Cappannelli, Marco Cardile, Deborah Cosmi, Tania Di Pasquale, Mariana Cappannelli, Jacopo Fagotti, Pietro Quadalti, Michele Marvardi, Roberto Marchetti, Euro Capponi

  https://doi.org/10.4081/itjm.2024.1840

  1649

  PDF: 668

  HTML: 40

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• Safety and efficacy of renal denervation utilizing standard bidirectional EP catheter: preliminary Vietnamese findings

  Tran Ba Hieu, Nguyen Ngoc Quang, Pham Manh Hung

  https://doi.org/10.4081/itjm.2024.1816

  1499

  PDF: 642

  HTML: 121

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• Vitamin D and intrauterine growth restriction: a cross-sectional study

  Fadhilah Arnan, Maisuri T. Chalid, Monika Fitria Farid, Efendi Lukas, Ellen Wewengkang

  https://doi.org/10.4081/itjm.2024.1833

  2046

  PDF: 806

  HTML: 111

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• Molecular and hematological spectrum of α-thalassemia in Saudi patients

  Raed Alserihi, Sarah Alswat, Heba Alkhatabi , Haitham M.H. Qutob, Elrashed B. Yasin, Talal Qadah

  https://doi.org/10.4081/itjm.2024.1837

  1520

  PDF: 580

  HTML: 168

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• Pharmacological interactions in novel oral anticoagulants, statins, and hypertension drugs in patients treated with direct-acting antivirals for hepatitis C: a Delphi Consensus project

  Ivan Gentile, Giancarlo Agnelli, Angelo Avogaro, Claudio Borghi, Alessia Ciancio, Ernesto Claar, Patrizio Pasqualetti, Pasquale Perrone Filardi

  https://doi.org/10.4081/itjm.2024.1846

  2749

  PDF: 557

  SUPPLEMENTARY MATERIAL: 318

  ACKNOWLEDGMENTS: 274

  HTML: 177

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• Association of immunoglobulins and complement levels with pemphigus in patients at the Khartoum Dermatology and Venereal Disease Hospital, Sudan

  Omer Osman Elhag, Mohammed S. Abduhameed, Ismaeel O. Khalid, AbdulAzeem Hijawi, Mohamed O. Andarawi, Saadalnour A. Mustafa, Adil A. Yousif, Shawgi A Elsiddig, Asaad Babker

  https://doi.org/10.4081/itjm.2024.1831

  1487

  PDF: 559

  HTML: 102

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• An uncommon case of postpartum venous thrombosis in a patient with hereditary angioedema. Patient from the ITACA Cohort (Italian Network for Hereditary and Acquired Angioedema)

  Francesco Giardino, Andrea Caruso, Simone Giosuè Longhitano, Lorena Domenica Campanello

  https://doi.org/10.4081/itjm.2024.1836

  1242

  PDF: 565

  HTML: 181

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• Sodium-glucose cotransporter 2 inhibition in patients with liver cirrhosis and diabetes: a possible role in ascites control?

  Aurelio Seidita, Francesca Mandreucci, Mirco Pistone, Silvia Calderone, Alessandra Giuliano, Marta Chiavetta, Lydia Giannitrapani, Roberto Citarrella, Maurizio Soresi, Anna Licata, Antonio Carroccio, Stella Compagnoni

  https://doi.org/10.4081/itjm.2024.1829

  2338

  PDF: 754

  SUPPLEMENTARY MATERIAL: 360

  HTML: 112

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• Assessing the effect of implementing a central line care bundle on central line-associated bloodstream infections in a tertiary hospital in Saudi Arabia

  Ohoud Alhumaidan, Zeina Alkudmani, Khaled Alnafee, Sabah Alshuhri, Bandar Alrashid, Jalwa Alkahtany, Afnan Almazrua, Salem Alghamdi

  https://doi.org/10.4081/itjm.2024.1783

  3503

  PDF: 1091

  SUPPLEMENTARY MATERIAL: 360

  HTML: 524

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• Clinical utility of echocardiography in internal medicine: a narrative review

  Nicola Mumoli, Stefania Marengo

  https://doi.org/10.4081/itjm.2024.1802

  2460

  PDF: 923

  HTML: 128

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• A misleading miscellanea: a COVID-19 patient with fever and cytopenia

  Pietro Bocchi, Lara Zerbini, Elisa Gnappi, Maurizio Ziliotti, Marco Pesci, Luisa Craviotto, Michele Meschi

  https://doi.org/10.4081/itjm.2024.1805

  1838

  PDF: 621

  HTML: 148

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• Ochrobactrum anthropi: a rare case of endocarditis

  Francesca Salvotti, Gilda Rossoni, Maria Chiara Pilia, Pietro Carleo, Veronika Kofler, Cristina Carmignani, Maria Grazia Marin, Fabrizio Paolo Bonfante, Irene Zagni

  https://doi.org/10.4081/itjm.2024.1821

  1773

  PDF: 632

  HTML: 124

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• Incidence and clinicopathological characteristics of breast cancer patients from a single center study

  Alaa Banjar

  https://doi.org/10.4081/itjm.2024.1820

  1972

  PDF: 633

  HTML: 132

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• Patent foramen ovale and stroke: a possible association with deep vein thrombosis

  Raffaele Natale, Luca Maria Capece, Sofia Donnarumma, Pasquale Madonna, Carolina Bologna, Domenico Birra, Antonietta De Sena, Marina Lugarà, Claudio De Luca, Mariavittoria Guerra, Gabriella Oliva, Fabio Granato Corigliano, Paolo Tirelli, Vincenzo Nuzzo

  https://doi.org/10.4081/itjm.2024.1801

  1775

  PDF: 786

  HTML: 155

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• The long-term impact of the COVID-19 pandemic on mental health and quality of life: a retrospective cohort study in northern Vietnam

  Nguyen Thi Hoa, Nguyen Van Tuan, Tran Thi Thu Ha, Nguyen Thanh Long, Nguyen Hoang Yen, Vu Son Tung, Tran Thien Thang, Tran Thi Ha An, Le Cong Thien, Le Thi Thu Ha, Le Thi Hoan

  https://doi.org/10.4081/itjm.2024.1809

  2365

  PDF: 718

  HTML: 154

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• La continuità di cura tra ospedale-territorio: strumenti e modelli a confronto

  Paola Gnerre, Andrea Montagnani

  1-64

  https://doi.org/10.4081/itjm.q.2024.6

  1989

  PDF: 3292

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• Diagnostic values of adenosine deaminase cytokines in fluid contributed to the detection of extrapulmonary tuberculosis

  Bui-Thi Thu Huong, Nguyen Minh Hien, Nguyen Tien Dung, Le-Thi Minh Hien, Luu Cong Thanh, Luu Vu Dung, Tran Khanh Chi, Nguyen-Van Khiem, Hoang Hai Yen

  https://doi.org/10.4081/itjm.2024.1810

  1291

  PDF: 542

  HTML: 16

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• Knowledge, perceptions, and practices of blood donation among undergraduate students at Gulf Medical University, United Arab Emirates: a cross-sectional study

  Asaad M.A. Babker, Kiran S Gopinath, Srija Manimaran, Ibrahim Ali Alsalkhadi, Praveen Kumar Kandakurti, Ahmed Luay Osman

  https://doi.org/10.4081/itjm.2024.1788

  1564

  PDF: 656

  SUPPLEMENTARY MATERIAL: 173

  HTML: 427

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• Comparative analysis of advanced polymerase chain reaction-based detection of Parvovirus B19 in first-trimester pregnant women at Thumbay Hospital, Ajman, United Arab Emirates

  Alaa M. Abdalhadi, Asaad Babker, Ahmed Luay Osman, Israa M. Abdalhadi, Mona A. Alblooshi, Fawzia A. AlObeidli, Israa O. Yousif, Hassan Higazi

  https://doi.org/10.4081/itjm.2024.1800

  938

  PDF: 475

  HTML: 87

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• Morphometric and clinical analysis and nutritional and dietary management of malnourished adult patients in the Marrakech Tensift Al Haouz region, Morocco

  Hiba Belmoudden, Btihaj Al Ibrahmi, Abdellatif Bour

  https://doi.org/10.4081/itjm.2024.1804

  735

  PDF: 372

  HTML: 37

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• Prevalence and distribution of dry eye disease among patients with type 2 diabetes in Kosovo

  Drilon Zekaj, Naim Jerliu, Floriana Kukaj-Zekaj, Ali Tonuzi

  https://doi.org/10.4081/itjm.2024.1799

  1439

  PDF: 567

  HTML: 3

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• A case of ankylosing spondylitis in female siblings

  Aigerim Abuova, Baglan Abdakhina, Aleksandr Glushan, Zhasken Smagulov, Bibigul Adilbekova, Svetlana Trofimova, Assel Meiramova

  https://doi.org/10.4081/itjm.2024.1797

  1119

  PDF: 379

  HTML: 297

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• Segmental arterial mediolysis: a challenging diagnosis in internal medicine

  Giulia Bombardieri, Alessandra Rustici, Michele Caselli, Chiara Chirico, Veronica Bocchi, Andrea Montagnani

  https://doi.org/10.4081/itjm.2024.1795

  913

  PDF: 434

  HTML: 413

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• Impressive weight loss induced by a very low-calorie ketogenic diet in a morbidly complex obese patient with a recent episode of acute kidney injury and advanced chronic kidney disease: a case report

  Vincenzo Trapanese, Maria Chiara Pelle, Maria Capria, Nazareno Carullo, Clara Vatalaro, Francesca Cosentino, Melania Melina, Maria Resilde Natale, Federica Giofrè, Franco Arturi

  https://doi.org/10.4081/itjm.2024.1787

  1435

  PDF: 527

  HTML: 141

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• Correlation between diet, body mass index, and lipid profile in Kosovar women treated for primary infertility

  Fatjona Gashi, Muhamet Kadrija, Zafer Gashi, Mila Arapcheska, Shkelzen Elezaj, Fitore Gashi, Fitim Gashi, Gentian Elezaj, Liridon Elezaj

  https://doi.org/10.4081/itjm.2024.1784

  1253

  PDF: 597

  HTML: 17

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• The value of computed tomography perfusion for assessing the response of hepatocellular carcinoma to transarterial chemoembolization

  Bui Quang Huynh, Nguyen Duy Hung, Le Thanh Dung, Nguyen-Thi Thu, Nguyen-Thi Hai Anh, Ngo Quang Duy, Nguyen Minh Duc

  https://doi.org/10.4081/itjm.2024.1768

  950

  PDF: 542

  HTML: 52

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• Concern for medical students due to their cell phones’ comparatively high contamination with Pantoea agglomerans bacteria with reduced sensitivity to some antimicrobials

  Ahmed E. Taha

  https://doi.org/10.4081/itjm.2024.1767

  1233

  PDF: 540

  HTML: 39

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• Metodologia clinica nei disturbi del paziente con comorbilità

  Francesco Dentali, Michele Meschi, Paola Gnerre, Tiziana Marcella Attardo

  1-44

  https://doi.org/10.4081/itjm.q.2024.5

  957

  PDF: 541

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• International Classification of Functioning, Disability and Health and goal attainment scale approach as academic tools at student-run free clinic for diabetic patients with international collaboration

  Faton T. Hoxha, Arb F. Hoxha, Toini Harra, Anu Myllyharju-Puikkonen, Nart F. Hoxha, Antigona Ukëhaxhaj

  https://doi.org/10.4081/itjm.2024.1774

  886

  PDF: 563

  HTML: 89

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• Screening for undernutrition in gastric bypass: a case study of four patients in the Marrakech Tensift Al Haouz region, Morocco

  Hiba Belmoudden, Btihaj Al Ibrahmi, Abdellatif Bour

  https://doi.org/10.4081/itjm.2024.1778

  806

  PDF: 497

  HTML: 92

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• High prevalence of malnutrition in an internal medicine department: results from the AMIDO study

  Paola Gnerre, Stefania Lingua, Marianna Farotto, Riccardo Mazzucco, Stefania Crivellari, Carlotta Bertolina, Fabio Giacchero, Paola Cerutti, Elena Seksich, Marinella Bertolotti, Antonio Maconi

  https://doi.org/10.4081/itjm.2024.1775

  1413

  PDF: 709

  HTML: 57

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• Multifactorial intestinal ischemia: a rare and undervalued diagnosis of abdominal pain

  Annadora Morena, Domenico Cirillo, Raffaele Natale, Clelia Nasti, Tullia Torella, Rossella Di Domenico, Fabrizio Pasanisi, Lidia Santarpia

  https://doi.org/10.4081/itjm.2024.1777

  976

  PDF: 591

  HTML: 76

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• Retroperitoneal laparoscopic radical nephrectomy in the treatment of renal cancer: a 5-year single-center experience in resource-scare setting

  Nguyen Minh An, Ngo Trung Kien, Nguyen Van Duc, Vo Hoang Long

  https://doi.org/10.4081/itjm.2024.1764

  2710

  PDF: 803

  HTML: 219

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• La sfida della prevenzione in medicina interna: a call for action | The challenge of prevention in internal medicine: a call for action

  Francesco Dentali, Sara Rotunno

  1-100

  https://doi.org/10.4081/itjm.q.2024.4

  1963

  PDF: 1104

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• Retrospective analysis on clinical characteristics and venous thromboembolism outcomes using bridging prophylaxis with low molecular weight heparin for thrombophilic women performing oocyte retrieval for assisted reproductive procedures: 15 years of experience

  Pierpaolo Di Micco, Corrado Lodigiani, Lidia Luciana Rota, Giuseppe Camporese, Ida Strina, Carlo Alviggi

  https://doi.org/10.4081/itjm.2024.1749

  938

  PDF: 704

  HTML: 32

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• Neutrophil-lymphocyte ratio as a biomarker for urinary tract infection in female patients at Thumbay University Hospital, Ajman, UAE

  Bissan Elattar, Rahaf Ka’ki, Samar Alansawi, Marwan Ismail, Hassan Higazi, Salah Hussein, Sara Mohammed Ali Mohammed, Salma Elnour, Nour Farajallah, Khalid Sukar

  https://doi.org/10.4081/itjm.2024.1751

  4097

  PDF: 562

  HTML: 2626

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• Complete revascularization in coronary artery bypass grafting with coronary artery endarterectomy: updated findings from Vietnam

  Huu Cong Nguyen, Hung Quoc Doan, Linh Hai T. Ngo, Uoc Huu Nguyen, Long Hoang Vo, Thanh Ngoc Le

  https://doi.org/10.4081/itjm.2024.1734

  963

  PDF: 507

  HTML: 40

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• Uso degli antibiotici nel fine vita Documento Intersocietario SICP - SIMIT - FADOI - SIMG

  Matteo Moroni, Massimo Melo, Raffaella Antonione, Massimo Fantoni, Roberto Luzzati, Massimiliano Lanzafame, Rita Murri, Fabio Gilioli, Francesco Dentali, Dario Manfellotto, Biancamaria Fraccaro, Luigi Patil

  1-24

  https://doi.org/10.4081/itjm.q.2024.3

  2064

  PDF: 1657

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• L’interprofessionalità medico-infermieristica in Medicina Interna I vantaggi della collaborazione medico-infermieristica nella pratica clinica

  Tiziana Marcella Attardo, Letizia Tesei, Dario Manfellotto, Francesco Dentali

  https://doi.org/10.4081/itjm.q.2024.2

  2044

  PDF: 1211

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• Il referral del paziente internistico in cardiologia riabilitativa - Position paper FADOI, ITACARE-P

  Francesco Dentali, Francesco Fattirolli, Paola Gnerre, Franco Mastroianni, Gian Francesco Mureddu, Marco Ambrosetti

  1-20

  https://doi.org/10.4081/itjm.q.2024.1

  1155

  PDF: 811

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  FADOI survey on chronic kidney disease and anaemia in internal medicine departments of Italian hospitals

  Pietro Bocchi, Andrea Montagnani, Michele Meschi, Fulvio Pomero, Paola Piccolo, Antonella Valerio, Gualberto Gussoni, Dario Manfellotto, Francesco Dentali, Chronic Kidney Disease and Anaemia in Internal Medicine (CKD-AIM) FADOI Study Group

  https://doi.org/10.4081/itjm.2023.1605

  1644

  PDF: 761

  HTML: 23

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  The management of heart failure: a FADOI survey in the setting of Internal Medicine Units

  Fernando Gallucci

  https://doi.org/10.4081/itjm.2023.1573

  2320

  PDF: 736

  HTML: 13

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  Position Paper FADOI-SIGG Nuove opportunità terapeutiche per ottimizzare la terapia con oppiacei e migliorare la qualità della vita dei pazienti

  Andrea Fontanella, Dario Manfellotto, Francesco Landi

  https://doi.org/10.4081/itjm.q.2021.s1

  2126

  PDF: 926

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  Consensus document ANMCO/FADOI/SIAARTI/SIC/SIMG/SIMI/SIMEU: The clinical-diagnostic and therapeutic pathway of patients with acute heart failure in the Emergency Department

  Mariavittoria Vescovo

  247-276

  https://doi.org/10.4081/itjm.2019.1230

  1911

  PDF: 1038

  HTML: 142

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  Doing more does not mean doing better: the FADOI contribution to the Slow Medicine program for a sustainable and wise healthcare system

  Luigi Lusiani, Roberto Frediani, Roberto Nardi, Andrea Fontanella, Mauro Campanini

  281-286

  https://doi.org/10.4081/itjm.2015.580

  1874

  PDF: 1040

  Appendix: 674

  HTML: 445

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