Original Articles

FADOI survey on chronic kidney disease and anaemia in internal medicine departments of Italian hospitals

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Published: 29 May 2023
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The presence of anaemia in patients with chronic kidney disease (CKD) is associated with decreased quality of life, along with increased morbidity, mortality, and hospitalization rates. This, in turn, affects healthcare costs and the utilization of medical resources. The mechanisms involved in anaemia of CKD are diverse and complex. They include reduced production of endogenous erythropoietin (EPO), absolute and/or functional iron deficiency (due to inflammation leading to elevated levels of hepcidin), the diminished response of the bone marrow to EPO due to uraemic toxins, the shortened lifespan of red blood cells (RBC), and deficiencies in vitamin B12 or folic acid. [...]

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Citations

Fishbane S, Spinowitz B. Update on anaemia in ESRD and earlier stages of CKD: core curriculum 2018. Am J Kidney Dis 2018;71:423-35.
Nakanishi T, Kimura T, Kuragano T. The Hepcidin-Anemia Axis: Pathogenesis of Anemia in Chronic Kidney Disease. Contrib Nephrol 2019;198:124-34.
Montagnani A, Frasson S, Gussoni G, et al. Anemia and iron in internal medicine: an Italian survey and a review on iron intravenous therapy in medical patients. Ital J Med 2022;16:1-9.
Takkavatakarn K, Thammathiwat T, Phannajit J, et al.The impacts of hypoxia-inducible factor stabilizers on laboratory parameters and clinical outcomes in chronic kidney disease patients with renal anemia: a systematic review and meta-analysis. Clin Kidney J 2023;16:845-58.

How to Cite



FADOI survey on chronic kidney disease and anaemia in internal medicine departments of Italian hospitals. (2023). Italian Journal of Medicine, 17(1). https://doi.org/10.4081/itjm.2023.1605