https://doi.org/10.4081/itjm.2023.1605

FADOI survey on chronic kidney disease and anaemia in internal medicine departments of Italian hospitals

Vol. 17 No. 1 (2023)
Published: 29 May 2023
chronic kidney disease, anaemia, internal medicine
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Authors

Pietro Bocchi
UOC Medicina Interna, Presidio Ospedaliero Azienda USL, Parma, Italy.
Andrea Montagnani
UOC Medicina Interna Grosseto, USL Toscana Sud-Est, Grosseto, Italy.
Michele Meschi
mmeschi@ausl.pr.it
UOC Medicina Interna, Presidio Ospedaliero Azienda USL, Parma, Italy.
Fulvio Pomero
UOC Medicina Interna, Ospedale “Michele e Pietro Ferrero” Verduno, Azienda ASL CN2, Verduno, Italy.
Paola Piccolo
UOC Medicina Interna, Ospedale Fatebenefratelli Isola Tiberina, Gemelli-Isola, Roma, Italy.
Antonella Valerio
Centro Studi FADOI, Roma, Italy.
Gualberto Gussoni
Centro Studi FADOI, Roma, Italy.
Dario Manfellotto
UOC Medicina Interna, Ospedale Fatebenefratelli Isola Tiberina, Gemelli-Isola, Roma, Italy.
Francesco Dentali
Dipartimento di Medicina Clinica e Sperimentale, Università dell’Insubria, Varese, Italy.
Chronic Kidney Disease and Anaemia in Internal Medicine (CKD-AIM) FADOI Study Group
Desirée Addesi, UO Medicina Generale, Azienda Ospedaliera “Pugliese-Ciaccio”, Catanzaro; Tiziana Marcella Attardo, UO Medicina Generale, Ospedale di Luino, ASST Sette Laghi; Stefano Bortolotti, UO Medicina Interna, Ospedale di Rovereto, Azienda Provinciale per i Servizi Sanitari, Provincia Autonoma di Trento; Roberta Buso, UO Medicina Interna 1, Azienda ULSS 2 Marca Trevigiana; Maria Ester Carugno, UO Medicina Interna e Nefrologia, Presidio Ospedaliero L’ Aquila, ASL 1 Abruzzo; Michele Caselli, UO Medicina Interna Grosseto – Azienda USL Toscana Sud-Est; Giuliano Cassataro, UO Medicina Interna, Fondazione Istituto “Giglio”, Cefalù; Giovanni Antonio Casu, Ospedale “Santissima Annunziata”, Azienda Ospedaliero-Universitaria, Sassari; Susanna Cozzio, UO Medicina Interna, Ospedale di Rovereto, Azienda Provinciale per i Servizi Sanitari, Provincia Autonoma di Trento; Ernesto De Menis, UO Medicina Interna 1, Azienda ULSS 2 Marca Trevigiana; Rosa Maria D’Errico, UO Medicina Interna, Ospedale “L. Bonomo”, Andria BAT; Fabiana Di Vincenzo, UO Medicina Interna e Nefrologia, Presidio Ospedaliero L’ Aquila, ASL 1 Abruzzo; Salvatore Di Simone, UO Medicina Interna e Geriatria, Ospedale “Parodi Delfino”, Colleferro, ASL Roma 5; Claudio Ferri, UO Medicina Interna e Nefrologia, Presidio Ospedaliero L’ Aquila, ASL 1 Abruzzo; Anna Fiengo, UO Medicina Interna, Ospedale di Saronno, ASST Valle Olona; Maria Serena Fiore, UO Medicina Interna, Ospedale “Sandro Pertini”, ASL Roma 2; Fernando Gallucci, UO Medicina Interna 3, AORN Cardarelli Napoli; Marco Giuliani, UO Medicina Interna, Azienda Ospedaliera “Santa Maria” di Terni; Federica Lorenzi, UO Medicina Interna e Geriatria, Ospedale “Parodi Delfino”, Colleferro, ASL Roma 5; Salvatore Lenti, UO Medicina Interna, Ospedale “L. Bonomo”, Andria BAT; Chiara Mastrobuoni, UO Medicina Interna 3, AORN Cardarelli Napoli; Matteo Parisotto, UO Medicina Interna 1, Azienda ULSS 2 Marca Trevigiana; Carmelo Pintaudi, UO Medicina Generale, Azienda Ospedaliera “Pugliese-Ciaccio”, Catanzaro; Maurizio Renda, UO Medicina Interna, Fondazione Istituto “Giglio”, Cefalù; Alba Sciascera, UO Medicina Interna, Ospedale di Saronno, ASST Valle Olona; Marco Spadaro, UO Medicina Interna, Ospedale “Sandro Pertini”, ASL Roma 2; Adalberto Vivaldo, UO Medicina Interna, ASL CN 1; Gaetano Vaudo, UO Medicina Interna, Azienda Ospedaliera “Santa Maria” di Terni; Carlo Andrea Usai, Ospedale “Santissima Annunziata”, Azienda Ospedaliero-Universitaria, Sassari, Italy.

The presence of anaemia in patients with chronic kidney disease (CKD) is associated with decreased quality of life, along with increased morbidity, mortality, and hospitalization rates. This, in turn, affects healthcare costs and the utilization of medical resources. The mechanisms involved in anaemia of CKD are diverse and complex. They include reduced production of endogenous erythropoietin (EPO), absolute and/or functional iron deficiency (due to inflammation leading to elevated levels of hepcidin), the diminished response of the bone marrow to EPO due to uraemic toxins, the shortened lifespan of red blood cells (RBC), and deficiencies in vitamin B12 or folic acid. [...]

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Citations

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Takkavatakarn K, Thammathiwat T, Phannajit J, et al.The impacts of hypoxia-inducible factor stabilizers on laboratory parameters and clinical outcomes in chronic kidney disease patients with renal anemia: a systematic review and meta-analysis. Clin Kidney J 2023;16:845-58. DOI: https://doi.org/10.1093/ckj/sfac271

How to Cite

Bocchi, P., Montagnani, A., Meschi, M., Pomero, F., Piccolo, P., Valerio, A., Gussoni, G., Manfellotto, D., Dentali, F., & in Internal Medicine (CKD-AIM) FADOI Study Group, C. K. D. and A. (2023). FADOI survey on chronic kidney disease and anaemia in internal medicine departments of Italian hospitals. Italian Journal of Medicine, 17(1). https://doi.org/10.4081/itjm.2023.1605
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