Original Articles

All Items

• Agreement between general practitioners and central reviewers on spirometry interpretation in primary care

  Giuseppe Misiano, Daniele Angioni, Andrea Pizzini, Daniela Ferrante, Mirko Parasiliti-Caprino, Vittorio Picottino, Marzio Uberti

  DOI https://doi.org/10.4081/itjm.2026.2657

  • 126 abstract views
  • 64 PDF

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• An algorithm for the management of chronic obstructive pulmonary disease patients in units of internal medicine

  Ombretta Para, Carmen Stabile, Donato Cinquepalmi, Maria Sandra Magnoni, Francesco Nasso, Flavio Tangianu, Mauro Silingardi, Antonella Valerio, Dario Manfellotto, Francesco Dentali

  DOI https://doi.org/10.4081/itjm.2025.1838

  • 2,420 abstract views
  • 2,009 PDF
  • 166 HTML

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• An innovative model of university cooperation in developing countries: results of five years of experience in internal medicine, health promotion and education

  Filomena Pietrantonio, Vera Kopsaj, Francesco Rosiello, Aurora Tomassoni, Luca Moriconi, Donatella Padua

  DOI https://doi.org/10.4081/itjm.2025.1941

  • 1,226 abstract views
  • 591 PDF
  • 41 HTML

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• Analysis of factors associated with comprehensive knowledge about HIV/AIDS transmission and prevention among people aged 15-49 years in Eswatini: evidence from the 2021-2022 multiple indicator cluster survey

  Ahmed Sulaiman, Abdelrahman Abukanna, Hafiz Almisbah, Haider Elmisbah, Kamal Hamad, Zakariya Mohammed, Sanaa Mohammed

  DOI https://doi.org/10.4081/itjm.2026.2490

  • 250 abstract views
  • 186 PDF
  • 87 SUPPLEMENTARY MATERIAL
  • 10 HTML

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• Analysis of the risk factors of hepatitis on the rate of recovery in pulmonary tuberculosis patients

  Muh Ridho Akbar, Irawaty Djaharuddin, Edward Pandu Wiriansya, Jamaluddin Madolangan, Harun Iskandar, Harry Akza Putrawan

  DOI https://doi.org/10.4081/itjm.2025.2064

  • 898 abstract views
  • 552 PDF
  • 4 HTML

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• Assessing tumor necrosis factor-α (-238 G/A and -308 G/A) genetic polymorphisms in sepsis susceptibility among cystic fibrosis patients

  Qahtan A. Mahdi, Jabbar S. Hassan, Abdulrhman M. Hassan Hadi, Ali Nayyef Umayra

  DOI https://doi.org/10.4081/itjm.2025.2021

  • 625 abstract views
  • 427 PDF
  • 45 HTML

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• Association between 25-hydroxy vitamin D insufficiency and serum uric acid levels compared to the gender and age categories

  Salah Eldin Omar Hussein, Awadh S. Alsubhi, Abdulrahman Algarni, Elryah I. Ali, Tagwa Yousif Elsayed Yousif, Ammar Abdelmola, Elyasa Elfaki, Wael Alzahrani, Ayman Hussien Alfeel

  DOI https://doi.org/10.4081/itjm.2025.2029

  • 1,756 abstract views
  • 566 PDF
  • 55 HTML

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• Chronic heart failure in an internal medicine outpatient setting: a retrospective real-world observational study of 30-day readmission and all-cause mortality

  Ettore Napoli, Laura Schiavon, Stefano Cuppini, Alberto Mazza

  DOI https://doi.org/10.4081/itjm.2026.2517

  • 1,515 abstract views
  • 451 PDF
  • 131 HTML

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• Cognitive impairment and associated metabolic and hormonal factors in women with polycystic ovarian syndrome: a Montreal Cognitive Assessment-based case-control study

  Muhanad Mahdi Dhumad, Farqad Bader Hamdan, Qasim Sharhan Al-Mayah

  DOI https://doi.org/10.4081/itjm.2025.2085

  • 1,149 abstract views
  • 617 PDF
  • 13 HTML

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• Continuity of care in acute coronary syndrome: why dedicated clinics for post-acute coronary syndrome management make the difference

  Maria Maiello, Francesco Proce, Cosima Caputo, Pasquale Palmiero

  DOI https://doi.org/10.4081/itjm.2025.2054

  • 444 abstract views
  • 440 PDF
  • 70 HTML

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• Correlation between neutrophil-to-lymphocyte ratio and soluble FMS-like tyrosine kinase 1 in pregnant women with preeclampsia

  Kiki Rizki Amelia, Efendi Lukas, Nurbani Bangsawan, Isharyah Sunarno, Retno Budiarti Farid, Sriwijaya Qadar

  DOI https://doi.org/10.4081/itjm.2025.1924

  • 974 abstract views
  • 571 PDF
  • 41 HTML

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• Correlation between obstructive sleep apnea syndrome and cardiovascular risk factors: a primary care strategy for early identification

  Manuel Monti, Maria Rosaria Manfredelli

  DOI https://doi.org/10.4081/itjm.2026.2480

  • 1,065 abstract views
  • 500 PDF
  • 4 HTML

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• Correlation of circulating diabetes markers with elevated serum antithyroglobulin antibodies in type 2 diabetes patients

  Batool Ibrahim Aljasmmi, Awadh S Alsubhi, Abdulrahman Algarni, Elryah I Ali, Ammar Abdelmola, Hussam Ali Osman, Abdelrahman Mohamed Ahmed Abukanna, Marwan Ismail, Asaad Babker, Salah Eldin Omar Hussein

  DOI https://doi.org/10.4081/itjm.2025.1961

  • 1,049 abstract views
  • 597 PDF
  • 69 HTML

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• Correlation of serum cardiolipin levels with physical activity in type 2 diabetes mellitus patients

  Ayesha Aslam, Shazia Bokhari, Riffat Mehboob, Uzma Rafi, Zeeshan Mehboob, Deema Sabtan, Mohammed M. Karami, Hani Sadaka Shalabi

  DOI https://doi.org/10.4081/itjm.2025.2363

  • 356 abstract views
  • 339 PDF
  • 30 HTML

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• Cytokine profile in COVID-19 infection: focus on interleukin-13, interleukin-33, and tumor necrosis factor-α as immunological markers

  Huda Saleem, Wafaa Hazim, Batool Mutar Mahdi, Mohammed S. Al-Iedani

  DOI https://doi.org/10.4081/itjm.2025.1823

  • 1,280 abstract views
  • 583 PDF
  • 290 SUPPLEMENTARY MATERIAL
  • 114 HTML

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• Determinants of hepatitis B vaccination coverage in children aged 12-23 months: evidence from the Multiple Indicator Cluster Survey

  Husham O. Elzein, Elryah I. Ali, Mohammed Suleiman Zaroog, Eltigani O.M. Omer, Kamal Elbssir Mohammed Ali, Eltayeb I.O. Elmahi, Sara H.M. Hamad, Zakariya M.S. Mohammed

  DOI https://doi.org/10.4081/itjm.2025.1976

  • 494 abstract views
  • 529 PDF
  • 40 HTML

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• Diagnostic and therapeutic care pathway of the Cardiac Network for Heart Failure

  Pasquale Palmiero, Matteo Durante, Maria Maiello, Valentina D’Andria, Cosima Caputo, Lucia Giordano

  DOI https://doi.org/10.4081/itjm.2025.1927

  • 1,231 abstract views
  • 624 PDF
  • 108 HTML

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• Effect of magnesium and potassium on rheumatoid arthritis factor and quality of life in patients with type 2 diabetes mellitus: a randomized control trial

  Hafiza Sonia Bibi, Uzma Rafi, Sidra Khalid, Riffat Mehboob, Anbreen Bibi, Hani Sadaka Shalabi, Mohammed A. Zaher, Samy A. Abusikkien

  DOI https://doi.org/10.4081/itjm.2025.1874

  • 2,160 abstract views
  • 915 PDF
  • 97 HTML

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• Employing the European Thyroid Imaging Reporting and Data System 2017 classification in a malignancy risk stratification system for thyroid nodules at Can Tho Oncology Hospital from 2021 to 2023

  Vo Van Kha, Tran Thi Huong Ly, Pham Thi Thanh Hoa, Vo Huynh Nhu

  DOI https://doi.org/10.4081/itjm.2025.1852

  • 2,177 abstract views
  • 923 PDF
  • 93 HTML

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• Epidemiological trends and determinants of hypertensive disorders in pregnancy: a 10-year retrospective study

  Desard Hashorva, Eva Muja, Eduart Hashorva

  DOI https://doi.org/10.4081/itjm.2025.2131

  • 633 abstract views
  • 388 PDF
  • 31 HTML

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• Evaluation of the renal function among sickle cell patients: a cross-sectional study

  Talal Qadah, Anwar Refaei

  DOI https://doi.org/10.4081/itjm.2025.1868

  • 890 abstract views
  • 831 PDF
  • 259 SUPPLEMENTARY MATERIAL
  • 85 HTML

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• Exploring some pro-inflammatory cytokines and adipokines as novel biomarkers in polycystic ovary syndrome

  Dlvin Akif Mustafa, Parween Abdulsamad Ismail

  DOI https://doi.org/10.4081/itjm.2025.2023

  • 1,202 abstract views
  • 467 PDF
  • 237 SUPPLEMENTARY MATERIAL
  • 79 HTML

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• Gender differences and post-pandemic mental health impacts: a mediation study on Vietnamese adolescents

  Thanh Long Nguyen, Victor Storm, Lam Toi Phung, Cong Thien Le, Thi Thu Ha Le, Thi Hoa Nguyen, Son Tung Vu, Thien Thang Tran, Minh Hanh Vu, Van Tuan Nguyen

  DOI https://doi.org/10.4081/itjm.2025.1888

  • 1,680 abstract views
  • 897 PDF
  • 273 SUPPLEMENTARY MATERIAL
  • 43 HTML

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• Gender disparities in career among internal medicine physicians: evidence from a national survey of members of FADOI

  Elena Barbagelata, Roberto Scondotto, Silvia Calderone, Cecilia Politi, Giuseppa Triolo

  DOI https://doi.org/10.4081/itjm.2026.2493

  • 1,771 abstract views
  • 686 PDF
  • 28 HTML

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• Immunohistochemical expression of transient receptor potential vanilloid 1 in World Health Organization grade IV astrocytoma, oral squamous cell carcinoma and bladder carcinoma

  Imrana Tanvir, Samina Qamar, Ahmad Alwazzan, Khurram Mehboob, Yousef Almehmadi, Ebtihal Ali Alharbi, Shadi Ahmed Alahmadi, Hafsa Adnan

  DOI https://doi.org/10.4081/itjm.2025.1893

  • 1,023 abstract views
  • 693 PDF
  • 127 HTML

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• Impact of tumor necrosis factor-α and interleukin 6 polymorphisms on type 2 diabetes mellitus Sudanese patients

  Elmutuz H. Elssaig, Abdalla Eltoum Ali, Mohammed A. Alsubai, Tarig M.S. Alnour, Eltayib H. Ahmed-Abakur, Aadil Yousif, Bashayr Mudhhi Alshehri, Fatmah Ali Awaji, Arwa Murdi Alanazi, Fai Fahad Alanazi, Abdullah Ali Alghamdi

  DOI https://doi.org/10.4081/itjm.2025.1967

  • 1,306 abstract views
  • 604 PDF
  • 4 HTML

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• Influence of L-citrulline supplementation along with conventional treatment and its effect on inflammatory markers in patients with non-alcoholic fatty liver disease

  Zergham Mazhar, Sana Farooq, Misbah Arshad, Sidra Khalid, Humaira Waseem, Shaista Jabeen, Siti Sarah Maidin, Adnan Essam Abukhashabah, Dahlia Mirdad, Mohammed Matoog Karami, Ali A Mousa

  DOI https://doi.org/10.4081/itjm.2026.2113

  • 1,646 abstract views
  • 451 PDF
  • 5 HTML

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• Internal-surgical co-management in emergency surgery: proposal of an organizational model

  Ombretta Para, Matteo Tomaiuolo, Asim Raza, Christian Carleo, Lucia Lipari, Alessio Giordano, Giovanni Alemanno, Paolo Prosperi, Carlo Nozzoli

  DOI https://doi.org/10.4081/itjm.2025.1886

  • 760 abstract views
  • 775 PDF
  • 4 HTML

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• Maximizing the success of percutaneous nephrolithotomy under spinal anesthesia by postoperative bleeding and fever prediction using demographic and intraoperative risk factors

  Muhammad Yasin Chaudhry, Muhammad Rizwan Farooqi, Asad Munir, Umaima Jalil, Razia Parveen Chaudhry, Andleeb Tariq, Rabia Noor, Umair Ahmed, Arbaz Munir

  DOI https://doi.org/10.4081/itjm.2025.2035

  • 703 abstract views
  • 487 PDF
  • 194 HTML

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• Mentzer Index and Red Cell Distribution Width Index in differentiating iron deficiency anemia and β-thalassemia trait

  Rabab H. Elshaikh, Ashok Kumar Sah, Abdelrahman Mohamed Abukanna, Abdulrahman Algarni, Ammar Abdelmola, Hussam Ali Osman, Tagwa Yousif Elsayed Yousif, Elryah I. Ali, Hiba Ali, Ayman Hussein Alfeel

  DOI https://doi.org/10.4081/itjm.2025.1892

  • 5,617 abstract views
  • 1,399 PDF
  • 6 HTML

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• Metformin’s therapeutic potential in adenomyosis: insights from interleukin 8 level

  Damas Hendriansyah, Nusratuddin Abdullah, Rudy B. Leonardy, Mardiah Tahir, Samrichard Rambulangi, Firdaus Hamid

  DOI https://doi.org/10.4081/itjm.2025.1940

  • 2,888 abstract views
  • 1,427 PDF
  • 5 HTML

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• Minimally invasive versus median sternotomy for mechanical mitral valve replacement: a single-center comparative study of treatment outcomes and quality of life

  The Binh Nguyen, Tran-Thuy Nguyen, Long Hoang Luong, Duc Hoang Nguyen, Cong Huu Nguyen, Ngoc Thanh Le, Bao Giang Kim

  DOI https://doi.org/10.4081/itjm.2025.1963

  • 3,569 abstract views
  • 675 PDF
  • 4 HTML

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• Organization of medical services for the Winter Olympic Games: the Milano-Cortina 2026 case

  Davide Croce, Giuseppe Massazza, Fabio Pigozzi, Diana Bianchedi, Thomas Toso

  DOI https://doi.org/10.4081/itjm.2026.2496

  • 2,471 abstract views
  • 564 PDF
  • 11 HTML

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• Orthostatic hypotension in hospitalized hypertensive patients admitted to internal medicine wards: rationale and design of the HYP-OP Study

  Claudio Ferri, Dario Manfellotto, Alberto Mazza, Francesco Dentali, Maria D’Avino, Antonella Valerio, Grzegorz Bilo, Gianfranco Parati, Andrea Fontanella, FADOI HYP-OP Study Group

  DOI https://doi.org/10.4081/itjm.2026.2494

  • 1,102 abstract views
  • 585 PDF
  • 27 HTML

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• Perceived stress in parents of children with neurodevelopmental disorders: psychometric properties of the stress measurement scale in the Moroccan dialect

  Sara Alouane, Zakaria Abidli, Ahmed O.T. Ahami, Soukaina El Idrissi, Jamila Riyahi

  DOI https://doi.org/10.4081/itjm.2025.1991

  • 847 abstract views
  • 539 PDF
  • 95 HTML

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• Relationship of adiponectin levels with the severity of chronic obstructive pulmonary disease

  Rismawaty Samonding, Muh Ilyas, Bulkis Natsir, Irawaty Djaharuddin, Sitti Nurisyah, Erwin Arief

  DOI https://doi.org/10.4081/itjm.2025.2015

  • 445 abstract views
  • 389 PDF
  • 2 HTML

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• Reproducibility and inter-observer variability of the internal jugular vein ultrasonographic assessment: a multicenter cross-sectional study

  Nicola Parenti, Elena Guidetti, Davide Allegri, Anna Lombardi, Rita Verdoliva, Paolo Vita, Ripalta Amato, Pasqualino Sirignano, Mauro Silingardi, Paolo Caraceni, Roberta Esposito, Francesco Bellanti, Alberto Maria Marra, Daniele Caggianiello, Carmine Savoia

  DOI https://doi.org/10.4081/itjm.2026.2547

  • 421 abstract views
  • 151 PDF
  • 67 SUPPLEMENTARY MATERIAL
  • 2 HTML

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• Risk factors for colorectal cancer in Albania: a case-control study

  Marsela Sina, Skerdi Prifti, Adea Kocollari, Ilir Akshija, Dorina Osmanaj, Gentiana Qirjako

  DOI https://doi.org/10.4081/itjm.2025.2007

  • 802 abstract views
  • 532 PDF
  • 51 HTML

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• Salivary creatinine is a promising noninvasive biomarker for chronic kidney disease: a case-control study

  Rabie Elagib Abdallah, Asma Anwar Mohammed, Afraa Ahmed Mohammed, Hala Mohammed Osman, Reel Nile Awad Elkareem, Hiba Mahgoub Ali Osman, Imadeldin Elfaki, Majdolin Mohammed Eltayeb Elsiddig, GadAllah Modawe

  DOI https://doi.org/10.4081/itjm.2026.2419

  • 1,429 abstract views
  • 594 PDF
  • 214 HTML

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• Serum transferrin level in type-2 diabetic patients in association with sociodemographic profile and dietary habits

  Anza Khan, Uzma Rafi, Riffat Mehboob, Sajid Hameed, Uzma Malik, Zainab Zubair, Imran Shahid

  DOI https://doi.org/10.4081/itjm.2025.1873

  • 1,083 abstract views
  • 679 PDF
  • 179 HTML

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• Standardized emergency department protocol for non-traumatic chest pain: experience from the USL Umbria 1 Health Authority

  Manuel Monti, Giovanni Dorilli, Laura Gasperini, Michele Marvardi

  DOI https://doi.org/10.4081/itjm.2026.2377

  • 680 abstract views
  • 626 PDF
  • 3 HTML

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• Systemic Immune-Inflammation Index as an independent predictor of in-hospital morbidity in diabetic patients with ST-elevation myocardial infarction

  Rafid B. Altaweel, Abdulameer A. Abdulhameed, Karzan M. Abdullah

  DOI https://doi.org/10.4081/itjm.2026.2563

  • 377 abstract views
  • 208 PDF
  • 11 HTML

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• The association of neutrophil-to-lymphocyte ratio with bronchiectasis severity assessed by the FACED classification in adults with post-tuberculosis bronchiectasis

  Fariz Nurwidya, Theresia Rasta Karina, Linda Mahardhika, Heidy Agustin

  DOI https://doi.org/10.4081/itjm.2026.2645

  • 96 abstract views
  • 37 PDF

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• The clinical value of fibrinogen and thromboelastography in the predictive assessment of the progression of persistent postpartum hemorrhage

  Huicong Yin, Huili Fan, Wenjuan Ma

  DOI https://doi.org/10.4081/itjm.2025.2109

  • 738 abstract views
  • 480 PDF
  • 145 SUPPLEMENTARY MATERIAL
  • 63 HTML

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• The effect of type 2 diabetes mellitus on clinical symptoms, sputum molecular test results, and lesions in thoracic photos of pulmonary tuberculosis patients

  Fikriatul Fadhilah, Erwin Arief, Nur Ahmad Tabri, Irawaty Djaharuddin, Arif Santoso, Jamaluddin Madolangan

  DOI https://doi.org/10.4081/itjm.2025.2048

  • 1,312 abstract views
  • 504 PDF
  • 3 HTML

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• The impact of diabetes on the outcomes of lower extremity arterial disease in patients with vascular surgical interventions in Kosovo

  Dion Haliti, Dea Haliti, Laura Leci Tahiri, Nora Shabani-Behrami, Elena Hajdari, Naim Haliti, Ragip Shabani, Fehim Haliti, Qenan Maxhuni, Rrahman Ferizi

  DOI https://doi.org/10.4081/itjm.2025.2095

  • 766 abstract views
  • 731 PDF
  • 179 SUPPLEMENTARY MATERIAL
  • 5 HTML

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• The incidence of bleeding in patients with nonvalvular atrial fibrillation using anticoagulants: a real-world report with the biggest Vietnamese data

  Bui The Dung, Cao Ngoc Mai Han, Tran Hoa, Nguyen Thanh Hien

  DOI https://doi.org/10.4081/itjm.2025.1807

  • 2,528 abstract views
  • 671 PDF
  • 4 HTML

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• The parental challenge: knowledge, attitudes, and practices on iron deficiency anemia in Tabuk

  Sawsan Mohammed Alblewi, Amerah M Alatawi, Faisal Mayudh Althobaiti, Adel Ali Alharfi, Faisal Mohammed Alamrani, Yazeed Mahmoud Ajwah, Omar Muslih Albalawi, Mohammed Majed Alquayr, Ariam Ebraheem Alshammari

  DOI https://doi.org/10.4081/itjm.2025.1946

  • 1,469 abstract views
  • 844 PDF
  • 259 HTML

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• The relationship between vitamin D levels and clinical symptoms and lesion size in chest radiographs of pulmonary tuberculosis in patients with comorbid diabetes mellitus

  Andi Nurrahma Ramli, Erwin Arief, Sitti Nurisyah, Jamaluddin Maddolangan, Harry Akza Putrawan, Nur Ahmad Tabri

  DOI https://doi.org/10.4081/itjm.2025.2053

  • 611 abstract views
  • 520 PDF
  • 56 HTML

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• The role of adiponectin in diabetic retinopathy and insulin resistance

  Shahad Kh. Hameed, Rawaa F. Jawad, Haidar Ahmad Shamran

  DOI https://doi.org/10.4081/itjm.2025.2049

  • 578 abstract views
  • 413 PDF
  • 34 HTML

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• The role of bronchial washing of transforming growth factor β1 as a prognostic biomarker of advanced stages of non-small cell lung cancer

  Nur Afifah Thamrin, Arif Santoso, Sitti Nurisyah, Irawaty Djaharuddin, Harun Iskandar

  DOI https://doi.org/10.4081/itjm.2025.2065

  • 917 abstract views
  • 571 PDF
  • 15 HTML

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• The role of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in assessing hypothyroidism Hashimoto’s thyroiditis

  Ruqeya Murad, Ayman H. Alfeel, Zulekha Shemote, Praveen Kumar, Asaad Babker, Ahmed Luay Osman, Abdelgdair A. Altoum

  DOI https://doi.org/10.4081/itjm.2025.1953

  • 1,681 abstract views
  • 747 PDF
  • 239 HTML

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• Utility of the aspirin and P2Y12 response assays to determine the effects of antiplatelet agents in patients with subdural hematoma undergoing neurosurgery

  Ombretta Para, Christian Carleo, Francesco Bucci, Lucia Lipari, Asim Raza, Edoardo Cesaroni, Chiara La Rovere, Simone Orlandini, Gastone Pansini, Alberto Parenti, Giovanni Muscas, Alessandro Della Puppa

  DOI https://doi.org/10.4081/itjm.2025.1926

  • 1,030 abstract views
  • 1,011 PDF
  • 3 HTML

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• Virus-induced asthma exacerbations in Vietnamese preschoolers

  Nguyen Thuy Van Thao, Tran Anh Tuan, Pham Hung Van, Le Thuong Vu

  DOI https://doi.org/10.4081/itjm.2025.1818

  • 983 abstract views
  • 691 PDF
  • 8 HTML

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