Original Articles
Vol. 19 No. 1 (2025)
https://doi.org/10.4081/itjm.2025.1882

The unseen connection: laryngeal carcinoma and thrombosis of the internal jugular vein

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: 17 February 2025
2137
Views
405
Downloads
156
HTML
Internal jugular vein, laryngeal carcinoma, venous thrombosis

Authors

Laura Leci-Tahiri
Faculty of Medicine, University of Prishtina; Clinic of Vascular Surgery, University Clinical Center of Kosovo, Prishtina, Kosovo.
Lisa Tahiri
https://orcid.org/0009-0003-0069-4225
Faculty of Medicine, University of Prishtina, Kosovo.
Valbona Zhjeqi
https://orcid.org/0000-0001-7862-9827
Faculty of Medicine, University of Prishtina; Institute of Public Health, University Clinical Center of Kosovo, Prishtina, Kosovo.
Emina Ramku
emine.ramku@uni-pr.edu
Faculty of Medicine, University of Prishtina; Clinic of Ear, Nose and Throat, University Clinical Center of Kosovo, Prishtina, Kosovo.

The occlusion of the internal jugular vein (IJV) in the context of laryngeal carcinoma is a rare but significant occurrence that may manifest at various stages of the disease. Laryngeal carcinoma, a form of cancer affecting the voice box, carries profound implications for individuals and society alike. Although the primary focus often lies in treating cancer, emerging research has uncovered an intriguing link between laryngeal carcinoma and jugular vein thrombosis (JVT), necessitating further investigation. We conducted a retrospective study spanning from January 2020 to December 2023, analyzing data from 60 patients who underwent surgery for laryngeal carcinoma at the Ear, Nose and Throat Department of the University Clinical Center of Kosovo. Among them, 9 patients were identified with concurrent IJV thrombosis, discovered incidentally during computed tomography examinations or based on clinical symptoms. Logistic regression analysis revealed associations between laryngeal carcinoma and JVT, emphasizing the importance of vigilance in diagnosis and management. Our findings underscore the need for heightened awareness and preventive measures, particularly in high-risk patients, to mitigate the impact of this interrelated condition. Early detection and intervention are crucial in optimizing outcomes for individuals confronting the dual challenges of laryngeal carcinoma and JVT.

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC
Ascher E, Salles-Cunha S, Hingorani A. Morbidity and mortality associated with internal jugular vein thromboses. Vasc Endovascular Surg 2005;39:335-9.
Leci-Tahiri L, Zherka-Saracini H, Tahiri A, Koshi A. Bilateral internal jugular vein thrombosis due to malignant tumor. J Med Case Rep 2018;12:42.
Haen P, Mege D, Crescence L, et al. Thrombosis risk associated with head and neck cancer: a review. Int J Mol Sci 2019;20:2838.
Karkos PD, Asrani S, Karkos CD, et al. Lemierre’s syndrome: a systematic review. Laryngoscope 2009;119:1552-9.
Panzironi G, Rainaldi R, Ricci F, et al. Gray-scale and color Doppler findings in bilateral internal jugular vein thrombosis caused by anaplastic carcinoma of the thyroid. J Clin Ultrasound 2003;31:111-5.
Oshinyemi P, Lee C, Gough-Palmer A, McKay-Davies I. IJV thrombophlebitis: be wary of the occult. BMJ Case Rep 2021;14:e238813.
Unsal EE, Karaca C, Ensarí S. Spontaneous internal jugular vein thrombosis associated with distant malignancies. Eur Arch Otorhinolaryngol 2003;260:39-41.
Hahn J, Nordmann-Kleiner M, Hoffmann TK, Greve J. Thrombosis of the internal jugular vein in the ENT-department - prevalence, causes and therapy: a retrospective analysis. Auris Nasus Larynx 2019;46:624-9.
Bandara AR, Wimalarathna H, Kalupahana R, Gunathilake SS. Internal jugular venous thrombosis due to Trousseau’s syndrome as the presenting feature of metastatic prostate carcinoma: a case report. J Med Case Rep 2016;10:104.
Wu MY, Hou YT, Ke JY, Yiang GT. Case of internal jugular vein thrombosis and fever: Lemierre’s syndrome or Trousseau’s syndrome? Ci Ji Yi Xue Za Zhi 2019;32:91-5.
Karim A, Knapp J, Nanda A. Internal jugular venous thrombosis as a complication after an elective anterior cervical discectomy: case report. Neurosurgery 2006;59:E705.
Motiee-Langroudi M, Amali A, Saedi B, et al. Internal jugular vein thrombosis following different types of neck dissection. Iran J Otorhinolaryngol 2020;32:343-7.
Modayil PCH, Panthakalam S, Howlett DC. Metastatic carcinoma of unknown primary presenting as jugular venous thrombosis. Case Rep Med 2009;2009:938907.
Serinken M, Karcioglu O, Korkmaz A. Spontaneous internal jugular vein thrombosis: a case report. Kaohsiung J Med Sci 2010;26:679-81.
Pata YS, Unal M, Gülhan S. Internal jugular vein thrombosis due to distant malignancies: two case reports and literature review. J Laryngol Otol 2008;122:318-20.

How to Cite



The unseen connection: laryngeal carcinoma and thrombosis of the internal jugular vein. (2025). Italian Journal of Medicine, 19(1). https://doi.org/10.4081/itjm.2025.1882
Copyright (c) 2025 the Author(s) Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.