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Italian Journal of Medicine

eISSN 1877-9352 - pISSN 1877-9344

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Editors-in-Chief: Francesco Dentali, Fulvio Pomero, Italy

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  • Chronic heart failure in an internal medicine outpatient setting: a retrospective real-world observational study of 30-day readmission and all-cause mortality

    Ettore Napoli, Laura Schiavon, Stefano Cuppini, Alberto Mazza
    29-04-2026
    https://doi.org/10.4081/itjm.2026.2517
    1262
    PDF: 199
    HTML: 103
  • When should antihypertensive drug treatment be started? Discrepancies between the 2023 European Society of Hypertension and the 2024 European Society of Cardiology guidelines

    Giuseppe Mancia, Guido Grassi, Sverre E. Kjeldsen
    16-04-2025
    https://doi.org/10.4081/itjm.2025.1981
    1827
    PDF: 603
    HTML: 0
  • A “cold” case of myxedema coma

    Elisa Eletto, Carmine Siniscalchi, Nicoletta Cerundolo, Beatrice Prati, Lorenzo Finardi, Riccardo Simoni, Alberto Parise, Antonio Nouvenne, Tiziana Meschi
    15-05-2025
    https://doi.org/10.4081/itjm.2025.1999
    1162
    PDF: 592
    HTML: 0
  • A case of pneumonia and sepsis in cirrhosis as paradigm of the problems in the management of bacterial infections in cirrhosis and of the limitations of current knowledge

    Manuel Tufoni, Alessandra Tovoli, Caterina Maggioli, Lucia Napoli, Carmen Serena Ricci, Marianna Mastroroberto, Giacomo Zaccherini, Paolo Caraceni
    209-214
    19-09-2013
    https://doi.org/10.4081/itjm.2013.209
    3863
    PDF: 1232
    HTML: 6041
  • Endovascular radiofrequency renal denervation in resistant hypertension: a single center experience

    Aurelio Negro, Antonio Manari, Rosaria Santi, Chiara Grasselli, Simona Davoli, Gianluca Pignatelli, Mila Menozzi, Franco Perazzoli
    29-34
    08-11-2013
    https://doi.org/10.4081/itjm.2013.174
    1406
    PDF: 841
    HTML: 373
  • Complete revascularization in coronary artery bypass grafting with coronary artery endarterectomy: updated findings from Vietnam

    Huu Cong Nguyen, Hung Quoc Doan, Linh Hai T. Ngo, Uoc Huu Nguyen, Long Hoang Vo, Thanh Ngoc Le
    24-05-2024
    https://doi.org/10.4081/itjm.2024.1734
    960
    PDF: 500
    HTML: 40
  • International Classification of Functioning, Disability and Health and goal attainment scale approach as academic tools at student-run free clinic for diabetic patients with international collaboration

    Faton T. Hoxha, Arb F. Hoxha, Toini Harra, Anu Myllyharju-Puikkonen, Nart F. Hoxha, Antigona Ukëhaxhaj
    27-08-2024
    https://doi.org/10.4081/itjm.2024.1774
    882
    PDF: 562
    HTML: 89
  • The hidden toll of war: long-term health risks at Europe’s doorstep

    Carmine Siniscalchi, Egidio Imbalzano, Pierpaolo Di Micco
    22-12-2025
    https://doi.org/10.4081/itjm.2025.2403
    246
    PDF: 174
    HTML: 0
  • Safety and efficacy of thromboprophylaxis with fondaparinux in elderly acutely ill medical patients with renal impairment: a retrospective single center study

    Federico Silvestri, Samantha Pasca, Marco Zaramella, Antonella Labombarda, Andrea Barbi, Mauro Desideri, Paolo Guidi, Adolfo Rogato, Matteo Bergamo, Giovanni Barillari
    287-292
    17-12-2013
    https://doi.org/10.4081/itjm.2013.287
    1755
    PDF: 1116
    HTML: 314
  • Proteinuria: pathophysiology, diagnostic and therapeutic approach

    Enrico Valvo
    116-122
    30-04-2013
    https://doi.org/10.4081/itjm.2009.116
    2838
    PDF: 11323
  • Is the lung a target organ in diabetes?

    Maurizio Marvisi, Emanuele Bassi
    113-115
    30-04-2013
    https://doi.org/10.4081/itjm.2009.113
    1099
    PDF: 1204
  • Serum transferrin level in type-2 diabetic patients in association with sociodemographic profile and dietary habits

    Anza Khan, Uzma Rafi, Riffat Mehboob, Sajid Hameed, Uzma Malik, Zainab Zubair, Imran Shahid
    18-02-2025
    https://doi.org/10.4081/itjm.2025.1873
    966
    PDF: 561
    HTML: 160
  • P22 | Granulomatosis with polyangiitis: plasmapheresis as a method to reduce permanent renal failure and incidence of side effects of rituxibab V. Bosco1, F. Mauceri1, V. Nicotra2, P. Gargano1, M. Carbone1, M. Romano1, S. Urso3 | 1Department of Clinical and Experimental Medicine, University of Catania, Garibaldi Hospital, Catania, 2Geriatric Department, Garibaldi-Nesima Hospital, Catania, 3UOSD Nephrology, Garibaldi-Nesima Hospital, Catania, Italy

    25-08-2025
    https://doi.org/10.4081/itjm.2025.2213
    239
  • A critical evaluation in the delivery of the ultrasound practice: the point of view of the Internal Medicine hospitalist

    Francesco Cipollini, Maria Luigia Cipollini
    1-4
    20-03-2015
    https://doi.org/10.4081/itjm.2015.522
    1921
    PDF: 1427
    HTML: 548
  • Primary antiphospholipid syndrome progressing to systemic lupus erythematosus: a case report

    Rocco Manganelli, Salvatore Iannaccone, Walter De Simone
    116-121
    30-04-2013
    https://doi.org/10.4081/itjm.2010.116
    945
    PDF: 1737
  • Delayed diagnosis of plasma cell disorder related Fanconi syndrome in young adults presenting as osteomalacia: report of two cases with normokalemia and normal haematological parameters at the time of presentation

    Joel Franklin, Praveen Valliyaparambil Pavithran, Neeraj Sidharthan, Seethalekshmy Nalumackal Vijayan, Nithya Abraham, Vadayath Usha Menon, Vasantha Nair, Harish Kumar
    12-01-2023
    https://doi.org/10.4081/itjm.2023.1559
    2050
    PDF: 663
    HTML: 113
  • Sodium-glucose co-transporter-2 inhibitor-associated non-diabetic ketoacidosis: a case report

    Vincenzo Trapanese, Francesco Maruca, Maria Resilde Natale, Federica Giofrè, Francesca Cosentino, Silvia Sergi, Giuseppe Armentaro, Valentino Condoleo, Franco Arturi
    04-04-2024
    https://doi.org/10.4081/itjm.2024.1716
    1375
    PDF: 808
    HTML: 284
  • Sex-gender and atrial fibrillation treatment in the AntiThrombotic Agents in Atrial Fibrillation (ATA-AF) study

    Cecilia Politi, Tiziana Ciarambino, Letizia Riva, Stefania Frasson, Donata Lucci, Gualberto Gussoni, Lucio Gonzini, Mauro Campanini, Michele Gulizia, Giuseppe Di Pasquale, Giovanni Mathieu, on behalf of ATA-AF Steering Committee and Investigators
    207-212
    16-02-2016
    https://doi.org/10.4081/itjm.2016.649
    1997
    PDF: 1589
    Appendix: 782
    HTML: 550
  • Postprandial hyperglycemia: a new frontier in diabetes management?

    Ada Maffettone, Massimo Rinaldi, Andrea Fontanella
    108-115
    20-06-2018
    https://doi.org/10.4081/itjm.2018.961
    3027
    PDF: 1712
    HTML: 3406
  • NT-proBNP correlates with the illness scores pneumonia severity index and CURB-65 in patients with pneumonia

    Dario Martolini, Eleonora Pistella, Enrico Carmenini, Claudio Santini
    37-40
    15-03-2017
    https://doi.org/10.4081/itjm.2017.728
    1825
    PDF: 1067
    HTML: 2047
  • Isolated dissection of the superior mesenteric artery: a case report and literature review

    Aurelio Seidita, Filippo Barbiera, Elena Murmura, Maria Accardi, Alberto D'Alcamo, Giusi Randazzo, Pasquale Mansueto, Antonio Carroccio, Delia Sprini
    56-63
    30-10-2013
    https://doi.org/10.4081/itjm.2013.168
    6815
    PDF: 1183
    HTML: 1705
  • A case of posterior reversible encephalopathy syndrome in the setting of post-partum preeclampsia with suppressed plasma aldosterone levels and plasma renin activity

    Aurelio Negro, Rosaria Santi, Chiara Grasselli, Simona Davoli, Franco Perazzoli
    300-304
    17-12-2013
    https://doi.org/10.4081/itjm.2013.300
    1457
    PDF: 956
    HTML: 393
  • Nosography of systemic inflammatory response syndrome, sepsis, severe sepsis, septic shock, and multiple organ dysfunction syndrome in internal medicine patients

    Silvia Spoto, Emanuele Valeriani, Sebastiano Costantino
    243-251
    22-09-2015
    https://doi.org/10.4081/itjm.2015.606
    2096
    PDF: 1390
    HTML: 599
  • Primary hepatic Ewing sarcoma: a very infrequent case report

    Ozturk Ates, Fatma Bugdaycı Basel, Nazan Bozdogan, Bulent Aksel, Omur Berna Oksuzoglu
    67-70
    27-10-2015
    https://doi.org/10.4081/itjm.2015.592
    1705
    PDF: 1051
    HTML: 735
  • Utility of the aspirin and P2Y12 response assays to determine the effects of antiplatelet agents in patients with subdural hematoma undergoing neurosurgery

    Ombretta Para, Christian Carleo, Francesco Bucci, Lucia Lipari, Asim Raza, Edoardo Cesaroni, Chiara La Rovere, Simone Orlandini, Gastone Pansini, Alberto Parenti, Giovanni Muscas, Alessandro Della Puppa
    14-07-2025
    https://doi.org/10.4081/itjm.2025.1926
    910
    PDF: 796
    HTML: 0
  • Antibiotic use in Departments of Internal Medicine of Lazio

    Dario Martolini, Maurizia Galiè, Anna Maria Santoro, Danilo Monno, Claudio Santini, David Terracina, on behalf of FADOI Lazio - Area of Infectious Diseases
    364-370
    28-11-2017
    https://doi.org/10.4081/itjm.2017.814
    1615
    PDF: 734
    HTML: 282
  • Acquired hemophilia A in a case of purple urine bag syndrome

    Vittoria Gammaldi, Anna Guida, Carolina Bologna, Antonietta De Sena, Marina Lugarà, Claudio De Luca, Fabio Granato Corigliano, Mariavittoria Guerra, Gabriella Oliva, Luca Mocerino, Aquilino Flavio Zarrella, Maria Gabriella Coppola, Vincenzo Nuzzo, Paolo Tirelli, Pasquale Madonna
    16-05-2024
    https://doi.org/10.4081/itjm.2024.1713
    973
    PDF: 461
    HTML: 90
  • Acute pancreatitis: confronting to improve

    Daniela Tirotta, Alessandro Franco, Francesca Talarico
    164-175
    14-06-2017
    https://doi.org/10.4081/itjm.2017.727
    1429
    PDF: 955
    HTML: 380
  • Lactic acidosis, hyperlactatemia and sepsis

    Andrea Montagnani, Roberto Nardi
    282-288
    15-12-2016
    https://doi.org/10.4081/itjm.2016.793
    6134
    PDF: 2226
    HTML: 6779
  • Subacute thyroiditis following influenza vaccine: a case report and literature review

    Munther S. Momani, Ayman A. Zayed, Faris G. Bakri
    384-386
    12-06-2015
    https://doi.org/10.4081/itjm.2015.542
    2071
    PDF: 1313
    HTML: 1528
  • Febuxostat: a new drug for an old disease. Do we really need it?

    Giovanni Gulli, Luigi de Filippis
    103-106
    30-04-2013
    https://doi.org/10.4081/itjm.2009.103
    1303
    PDF: 1580
  • Multiple contemporary arterial dissection in Ehlers-Danlos syndrome type IV

    Anna Rocci, Enrico Paganelli, Angelo Rossetti, Carla Marcato, Davide Martorana, Maria Ilaria Tassoni, Roberto Quintavalla
    77-81
    20-03-2015
    https://doi.org/10.4081/itjm.2015.494
    2217
    PDF: 1239
    HTML: 915
  • CO25 | The prevalence of peripheral artery disease in patients with chronic kidney disease in the Internal Medicine department S. Marino, G. Fabro, D. Mastroiacovo, A. Bonaventura, F. Dentali | UO Medicina Generale 1, Ospedale di Circolo Fondazione Macchi, Varese, Italy

    25-08-2025
    https://doi.org/10.4081/itjm.2025.2177
    219
  • Fatal transfusion-related acute lung injury type II following red blood cell transfusion in a cancer patient with suspected endocarditis: a case report

    Paolo Tirelli, Gianluigi Cuomo, Domenico Birra, Claudio De Luca, Antonietta De Sena, Fabio Granato Corigliano, Mariavittoria Guerra, Carmine Fierarossa, Benedetta Tartaglia, Vittoria Gammaldi, Carolina Bologna, Gabriella Oliva, Pasquale Madonna, Vincenzo Nuzzo
    03-02-2026
    https://doi.org/10.4081/itjm.2026.2407
    595
    PDF: 278
    HTML: 10
  • A dangerous mixture

    Anna Piva, Alessio Filippi, Natalino Simioni
    262-264
    17-03-2014
    https://doi.org/10.4081/itjm.2014.475
    2100
    PDF: 1204
    HTML: 464
  • The clinical value of fibrinogen and thromboelastography in the predictive assessment of the progression of persistent postpartum hemorrhage

    Huicong Yin, Huili Fan, Wenjuan Ma
    16-10-2025
    https://doi.org/10.4081/itjm.2025.2109
    476
    PDF: 281
    SUPPLEMENTARY MATERIAL: 110
    HTML: 42
  • Multidrug-resistant Gram-negative bacteria-resistant infections: epidemiology, clinical issues and therapeutic options

    Matteo Bassetti, Davide Pecori, Maddalena Peghin
    364-375
    15-12-2016
    https://doi.org/10.4081/itjm.2016.802
    4850
    PDF: 1881
    HTML: 3616
  • P29 | Orthostatic hypotension in hypertensive patients hospitalized in Internal Medicine: baseline results of IpOp study R. Buso1, C. Ferri2, A. Mazza3, A. Moggi Pignone4, F. Dentali5, M. D’Avino6, S. Maule7, M. Rattazzi1, P. Minuz8, D. Manfellotto9 | 1Ospedale Cà Foncello, Università degli Studi di Padova, Dipartimento di Medicina, DIMED, Medicina Interna 1, Treviso, 2University of L’Aquila, MeSVA Department, San Salvatore Hospital, UOC of Internal Medicine and Nephrology, 3ESH Excellence Hypertension Centre and Dept. of Internal Medicine, Santa Maria Regina degli Angeli General Hospital, Adria (RO), AULSS 5 Polesana, 4Azienda Ospedaliera-Universitaria Careggi, Firenze Dipartimento di Medicina Clinica e Sperimentale, SOD complessa di Medicina Interna 4, 5Università dell’Insubria, Dipartimento di Area Medica, Asst Sette Laghi, Medicina Generale, Varese, 6Ospedale Cardarelli, Napoli, 7Ospedale “Città della Salute”, Torino, 8UOC General Medicine C, Department of Medicine, AOUI Verona and University of Verona, 9Internal Medicine Department, Isola Tiberina Hospital Gemelli Isola, Rome, Italy

    26-08-2025
    https://doi.org/10.4081/itjm.2025.2221
    205
  • The anemia of the old and oldest-old patients hospitalized in Internal Medicine: a very high rate of anemia of chronic disease and multifactorial anemia

    Federico Silvestri, Renzo Pozzo, Andrea Barbi, Antonella Labombarda, Marco Zaramella, Igor Bramuzzo, Elisa Mansutti, Laura Perale, Adolfo Rogato, Francesca Zanini
    143-150
    15-05-2020
    https://doi.org/10.4081/itjm.2020.1282
    1872
    PDF: 764
    HTML: 29
  • Adipocytokines in metabolically healthy obesity

    Sofia G. Shulkina, Elena N. Smirnova, Maxim I. Yudin, Mikhail A. Osadchuk, Maxim V. Trushin
    169-175
    06-09-2019
    https://doi.org/10.4081/itjm.2019.1075
    1843
    PDF: 747
    HTML: 60
  • Hypoferritinemia in anemic patients attending a tertiary hospital in Maiduguri, Nigeria

    Amos Dangana, Idris Abdullahi Nasir, Jessy Thomas Medugu, Peter Musa Omale, Bibiana Nonye Egenti
    191-195
    10-08-2016
    https://doi.org/10.4081/itjm.2016.751
    2591
    PDF: 1077
    HTML: 551
  • Transient leukocytosis in Emergency Room: an overlooked issue

    Giampiera Bertolino, Federica Quaglia, Luigia Scudeller, Iride Ceresa, Carlo L. Balduini
    41-47
    15-03-2017
    https://doi.org/10.4081/itjm.2017.724
    2390
    PDF: 1281
    HTML: 5226
  • Iatrogenic hypomagnesemia: an underestimated clinical problem

    Antonio Villa, Paolo Zanada, Adriana Pellegrino, Gabriella Nucera, Elena Martinoli, Annamaria Boschiero, Francesca Campanini
    287-289
    22-09-2015
    https://doi.org/10.4081/itjm.2015.521
    25378
    PDF: 1070
    HTML: 982
  • Acute severe renal failure in a patient receiving apixaban: a case report

    Attilia Maria Pizzini, Chiara Fantoni, Stefania Zaccaroni, Mauro Silingardi
    09-04-2024
    https://doi.org/10.4081/itjm.2024.1718
    1125
    PDF: 576
    HTML: 82
  • The diagnostic pathway embolism: from the Emergency Department to the Internal Medicine Unit

    Attilia Maria Pizzini, Daniela Galimberti, Stefano De Pietri, Mauro Silingardi, Maria Cristina Leone, Annamaria Ferrari, Ido Iori
    4-9
    22-03-2016
    https://doi.org/10.4081/itjm.2016.546
    2096
    PDF: 1294
    HTML: 544
  • Correlation between diet, body mass index, and lipid profile in Kosovar women treated for primary infertility

    Fatjona Gashi, Muhamet Kadrija, Zafer Gashi, Mila Arapcheska, Shkelzen Elezaj, Fitore Gashi, Fitim Gashi, Gentian Elezaj, Liridon Elezaj
    24-09-2024
    https://doi.org/10.4081/itjm.2024.1784
    1252
    PDF: 591
    HTML: 17
  • Efficacy of intranasal fluticasone propionate nano nasal spray in management of chronic rhinitis: a randomized clinical trial

    Yasir Mehmood, Hira Shahid
    30-12-2022
    https://doi.org/10.4081/itjm.2022.1545
    2725
    PDF: 745
    HTML: 171
  • A rare disease causing carpal tunnel syndrome

    Paolo Agostinis, Michele Battellino
    23-10-2025
    https://doi.org/10.4081/itjm.2025.2137
    450
    PDF: 319
    HTML: 29
  • Doing more does not mean doing better: the FADOI contribution to the Slow Medicine program for a sustainable and wise healthcare system

    Luigi Lusiani, Roberto Frediani, Roberto Nardi, Andrea Fontanella, Mauro Campanini
    281-286
    22-09-2015
    https://doi.org/10.4081/itjm.2015.580
    1871
    PDF: 1032
    Appendix: 667
    HTML: 445
  • New antibiotic development: barriers and opportunities

    Ercole Concia, Fulvia Mazzaferri, Maddalena Cordioli
    255-271
    15-12-2016
    https://doi.org/10.4081/itjm.2016.790
    3621
    PDF: 2023
    HTML: 2057
  • A case report of bladder cancer-related acquired hemophilia A

    Gaia Dragoni, Nicolò Ferraroni, Raffaella Benedetti, Aderville Cabassi, Davide Imberti
    17-06-2025
    https://doi.org/10.4081/itjm.2025.2019
    621
    PDF: 373
    HTML: 61
  • Hypertension and emergency medicine: an update

    Michele Meschi, Simona Detrenis, Laura Bianchi, Marcella Saccò, Marcello Bertorelli, Sarah Pioli, Francesca Boffetti, Francesca Spagnoli, Enrico Fiaccadori, Alberto Caiazza
    6-13
    04-03-2013
    https://doi.org/10.4081/itjm.2013.6
    2091
    PDF: 1010
    HTML: 392
  • Short versus long course antibiotic therapy for acute pyelonephritis in adults: a systematic review and meta-analysis

    Franco Berti, Tiziana Marcella Attardo, Salva Piras, Letizia Tesei, Daniela Tirotta, Michela Tonani, Greta Castellini, Silvia Gianola, Silvia Minozzi
    39-50
    20-03-2018
    https://doi.org/10.4081/itjm.2018.840
    3996
    PDF: 1525
    Appendix: 638
    HTML: 1090
  • P68 | A rare case of diarrhea A. Fraghì, D. Belli, C. Seguiti, T. Sabatini, S.M. Milluzzo, P. Cesaro, G. Rossi | Fondazione Poliambulanza di Brescia, Italy

    26-08-2025
    https://doi.org/10.4081/itjm.2025.2261
    175
  • Quantifying treatment effect: relative and absolute measures in clinical research

    Alberto Maino, Lorenza Bertù, Alessandro Squizzato, Paola Piccolo, Fulvio Pomero
    16-04-2026
    https://doi.org/10.4081/itjm.2026.2386
    683
    PDF: 400
    HTML: 105
  • Rare but possible: clopidogrel-induced pancytopenia

    Pietro Bocchi, Pasquale Gianluca Giuri, Achiropita Bovino, Alessia Casola, Simona Detrenis, Marcello Bertorelli, Michele Meschi, Giancarlo Mangè
    10-10-2023
    https://doi.org/10.4081/itjm.2023.1660
    1799
    PDF: 767
    HTML: 256
  • P41 | Efficacy and safety of Roxadustat in patients with anemia of dialysis-dependent chronic kidney disease with or without inflammation: pooled analysis of four phase 3 studies G. Choukroun1, A. Harkavyi2, V. Santos3, A. Jiletcovici3, L. Del Vecchio4 | 1CHU Amiens Picardie and Jules Verne University, Amiens, France, 2Astellas Pharma Europe, Addlestone, UK, 3Astellas Pharma, Inc., Northbrook, USA, 4Sant’Anna Hospital, ASST Lariana, Como, Italy

    26-08-2025
    https://doi.org/10.4081/itjm.2025.2233
    479
  • Asymptomatic endoalveolar hemorrhage in a young male

    Alain Kafyeke, Giovanni Pomponio, Andrea Balloni, Simona Gambini, Francesca Barbisan, Armando Gabrielli
    137-139
    23-06-2016
    https://doi.org/10.4081/itjm.2016.594
    1549
    PDF: 1198
    HTML: 421
  • CO10 | The Volemia Fragile Project: internal and geriatric medicine specialists left the hospital to work in the local community. The experience of the Cure Primarie Unit, Pieve di Soligo District, AULSS 2, Veneto Region A. Da Rold1, A. Vendrame1, D. De Nardo1, S. Sant1, B. Favero2, P. Zaros2, P. Bonato3, M. Mosele1 | 1Cure Primarie, Distretto di Pieve di Soligo, Azienda ULSS 2 Marca Trevigiana, 2ADI - Cure Primarie, Distretto di Pieve di Soligo, Azienda ULSS 2 Marca Trevigiana, 3Direzione del Distretto di Pieve di Soligo, Azienda ULSS 2 Marca Trevigiana, Italy

    25-08-2025
    https://doi.org/10.4081/itjm.2025.2162
    247
  • Circadian blood pressure rhythm and intimal-medial thickness changes in non-dipper normotensive patients

    Massimiliano Rocchietti March, Claudia Maggiore, Gerardo Salerno, Agostino De Venanzi, Elena Scaramucci, Patrizia Cardelli
    360-363
    31-07-2017
    https://doi.org/10.4081/itjm.2017.819
    1494
    PDF: 764
    HTML: 231
  • P77 | A rare late side effect of radiotherapy G. Gottardi1, L. Bonanni2, M. Giannoccaro2, F. Serafini2, F. Presotto2 | 1Dipartimento di Medicina, Università di Padova, 2UOC Medicina Interna, Ospedale dell’Angelo (Mestre-Venezia), Italy

    26-08-2025
    https://doi.org/10.4081/itjm.2025.2270
    195
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Italian Journal of Medicine

is the official journal of the Federation of Associations of Hospital Doctors on Internal Medicine (FADOI) and it is published by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.

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