https://doi.org/10.4081/itjm.2021.1340

Role of NASA 10-minute Lean Test in diagnosing postural orthostatic tachycardia syndrome: a preliminary study in young population

Vol. 15 No. 2 (2021)
Submitted: 20 June 2020
Accepted: 30 December 2020
Published: 25 January 2021
Postural orthostatic tachycardia syndrome, adolescents, Lean Test, NASA.
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Authors

Musharaf Bashir
dr.musharaf.mb@gmail.com
https://orcid.org/0000-0001-7836-3715
Department of Physiology, GMC and SMHS Hospital, Srinagar, JK, New Delhi, India.
Himani Ahluwalia
https://orcid.org/0000-0002-5494-394X
Department of Physiology, VMMC and Safdarjung Hospital, New Delhi, India.
Tazeen Khan
https://orcid.org/0000-0003-3284-768X
Department of Physiology, GMC and SMHS Hospital, Srinagar, JK, New Delhi, India.
Sheikh Imran Sayeed
https://orcid.org/0000-0002-6639-0828
Department of Physiology, GMC and SMHS Hospital, Srinagar, JK, New Delhi, India.

Postural orthostatic tachycardia syndrome (POTS) is a form of autonomic imbalance characterized by abnormally increased heart rate (HR) and various symptoms of orthostatic intolerance (OI). This study aimed to determine POTS in adolescents using the National Aeronautics and Space Administration (NASA) 10-minute Lean Test. This cross-sectional study was conducted at Government Medical College, Srinagar, JK, India, between October 2017 and November 2019. Adolescents with symptoms of OI were enrolled for this study, and the NASA 10-minute Lean Test was performed. Characteristics of the POTS group were compared with the non-POTS group. There was a significant difference in BMI (P<0.0001) between the POTS and non-POTS groups. However, the number of females with features of POTS was greater than males. There was a significant difference in resting HR between the two groups (P<0.0001). During upright posture, there was a significant difference in maximum upright HR between the two groups (P<0.0001), the highest increment in upright HR also differed significantly (P<0.0001). POTS group had significantly higher HR than the non-POTS group. It may be inferred from this preliminary study that NASA 10- minute Lean Test can be used to diagnose POTS.

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Crossref
Scopus
Google Scholar
Europe PMC
Fedorowski A. Postural orthostatic tachycardia syndrome: clinical presentation, etiology and management. J Intern Med 2019;285:352-66. DOI: https://doi.org/10.1111/joim.12852
Boris JR. Postural orthostatic tachycardia syndrome in children and adolescents. Auton Neurosci Basic Clin 2018;215:97-101. DOI: https://doi.org/10.1016/j.autneu.2018.05.004
Stewart JM, Boris JR, Chelimsky G, et al. Pediatric disorders of orthostatic intolerance. Pediatrics 2018;141:1. DOI: https://doi.org/10.1542/peds.2017-1673
Shaw BH, Stiles LE, Bourne K, et al. The face of postural tachycardia syndrome - insights from a large cross-sectional online community-based survey. J Intern Med 2019;286:438-48. DOI: https://doi.org/10.1111/joim.12895
Bryarly M, Phillips LT, Fu Q, et al. Postural orthostatic tachycardia syndrome. JACC 2019;73:1207-28. DOI: https://doi.org/10.1016/j.jacc.2018.11.059
Tao C, Wenxin L, Lin J, et al. Long term outcomes of children and adolescents with postural orthostatic tachycardia syndrome after conventional treatment. Front Pediatr 2019;7:00261. DOI: https://doi.org/10.3389/fped.2019.00261
McDonald C, Koshi S, Busner L, et al. Postural tachycardia syndrome is associated with significant symptoms and functional impairment predominantly affecting young women: a UK perspective. BMJ Open 2014;4:e004127. DOI: https://doi.org/10.1136/bmjopen-2013-004127
Bateman L. Simple way to assess orthostatic intolerance; Bateman Horne Center. Available from: www.BatemanHorneCenter.org Accessed: Aug, 2017.
Moon J, Do-Yong K, Jung-Ick B, et al. Orthostatic intolerance symptoms are associated with depression and diminished quality of life in patients with postural tachycardia syndrome. BioMed Central 2016;14:144. DOI: https://doi.org/10.1186/s12955-016-0548-x
Singer W, Sletten DM, Opfer-Gehrking TL, et al. Postural tachycardia in children and adolescents: what is abnormal? J Pediatr 2012;160:222-6. DOI: https://doi.org/10.1016/j.jpeds.2011.08.054
Kanjwal K, Karabin B, Kanjwal Y, Grubb BP. Autonomic dysfunction presenting as postural orthostatic tachycardia syndrome in patients with multiple sclerosis. Int J Med Sci 2010;7:62-7. DOI: https://doi.org/10.7150/ijms.7.62
Anjum I, Sohail W, Hatipoglu B, Wilson R. Postural orthostatic tachycardia syndrome and its unsual presenting complaints in women: a literature minireview. Cureus 2018;10:e2435. DOI: https://doi.org/10.7759/cureus.2435
Kavi L, Gammage MD, Karabin BL. Postural tachycardia syndrome: multiple symptoms, but easily missed. Br J Gen Pract 2012;62:286-87. DOI: https://doi.org/10.3399/bjgp12X648963
Pederson JL, Brook JB. Health related quality of life and suicide risk in postural tachycardia syndrome. Clin Auton Res 2017;27:75-81. DOI: https://doi.org/10.1007/s10286-017-0399-5
Lin J, Zhao H, Jiao F. Body mass index is decresed in children and adolescents with postural tachycardia syndrome. Turk J Pediatr 2019;61:52-8. DOI: https://doi.org/10.24953/turkjped.2019.01.009
Roerink ME, Lenders JWM, Schmits IC, et al. Postural orthostatic tachycardia is not a useful diagnostic marker for chronic fatigue syndrome. J Intern Med 2017;282:179-88. DOI: https://doi.org/10.1111/joim.12564

How to Cite

Bashir, M., Ahluwalia, H., Khan, T., & Sayeed, S. I. (2021). Role of NASA 10-minute Lean Test in diagnosing postural orthostatic tachycardia syndrome: a preliminary study in young population. Italian Journal of Medicine, 15(2). https://doi.org/10.4081/itjm.2021.1340
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