From sciatica pain to a complex diagnosis: a case of pyomyositis and chronic lymphocytic leukemia

Submitted: 7 October 2020
Accepted: 9 February 2021
Published: 24 September 2021
Abstract Views: 955
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We described a case of a 50-year-old man who presented severe low back and leg pain that quickly evolved in severe septic shock. Clinical workouts led us to diagnose a rare condition as pyomyositis because of the identification of Staphylococcus aureus septicemia and multiple muscle collections. Although this rare condition rarely occurs in temperate climates, its prevalence recently increased and is often associated with an immunocompromised condition. In this case, the investigation of an immunological impairment revealed an underlying chronic lymphocytic leukemia/small cell non-Hodgkin lymphoma.



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Comegna L, Guidone PI, Prezioso G, et al. Pyomyositis is not only a tropical pathology: a case series. J Med Case Rep 2016;10:1-6. DOI:
González Gómez B, Vargas Pérez M, del Rosal Rabes T, et al. Pyomyositis in a non-tropical area. 12 years of cased-based experience. An Pediatría (English Ed.) 2017;87:350-1. DOI:
Manikandan V, Mehrotra S, Anand S, Maurya V. Tropical pyomyositis: revisited. Indian J Surg 2017;79:33-7. DOI:
Gibson RK, Rosenthal SJ, Lukert BP. Pyomyositis. Increasing recognition in temperate climates. Am J Med 1984;77:768-72. DOI:
Christin L, Sarosi GA. Pyomyositis in North America: case reports and review. Clin Infect Dis. 1992;15:668-77. DOI:
Chauhan S, Jain S, Varma S, Chauhan SS. Tropical pyomyositis (myositis tropicans): current perspective. Postgrad Med J. 2004;80:267-70. DOI:
Charitidis C, Stampolidis N, Falidas E, Tsochataridis E. Multifocal pyomyositis and meningitis after bone marrow biopsy in a diabetic patient. G Chir. 2011;32:185-7.
Xipell M, Ventura-Aguiar P, Revuelta I, et al. Pyomyositis in a patient with IgA nephropathy and kidney transplant. Case Rep Transplant 2019;2019:1-3. DOI:
Takebayashi K, Sonoda H, Shimizu T, et al. Pyomyositis at the surgical site in a patient with chronic myeloid leukemia: a case report and literature review. World J Surg Oncol 2016;14:116. DOI:
Falagas ME, Rafailidis PI, Kapaskelis A, Peppas G. Pyomyositis associated with hematological malignancy: case report and review of the literature. Int J Infect Dis 2008;12:120-125. DOI:
Navinan MR, Yudhisdran J, Kandeepan T, Kulatunga A. Tropical pyomyositis as a presenting feature of subclinical leukemia: a case report. J Med Case Rep 2015;9. DOI:
Jurado-Camino T, Córdoba R, Esteban-Burgos L, et al. Chronic Lymphocytic leukemia: a paradigm of innate immune cross-tolerance. J Immunol 2014;194:719-27. DOI:

How to Cite

Magnani, O., Caiti, M., Cenni, E., & Moscatelli, P. (2021). From sciatica pain to a complex diagnosis: a case of pyomyositis and chronic lymphocytic leukemia. Italian Journal of Medicine, 15(3).