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This paper reports a very rare case of isolated ulcerative lesion of the palate in a patient with type-2 diabetes mellitus. The patient refused to run any radiological tests, other than the periapical radiograph. This rendered the diagnostic dilemma more challenging. Through histochemical and immunohistochemical stains, the case could be non-invasively diagnosed as caliberpersistent artery. All differential diagnoses were excluded based on concrete findings.
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