Primary insulin autoimmune syndrome in an Italian woman: a case report

Submitted: 12 February 2014
Accepted: 30 July 2014
Published: 8 May 2015
Abstract Views: 1520
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Insulin autoimmune syndrome (IAS) is a rare syndrome characterized by fasting or postprandial hypoglycemia, high levels of anti-insulin antibodies and high concentration of total serum immunoreactive insulin. It is relatively known in Japan, rare in remaining Asia and it is extremely uncommon in Western countries, being characterized by a different race-related incidence and associated with HLADR4 alleles. Usually IAS is related to particular drugs, or to autoimmune, rheumatologic or hematological diseases, while it is very rare as a primary form. Here we described a case of an Italian woman affected by a primary form of Hirata syndrome.

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Balestrieri, A., Magnani, E., Ragazzini, C., & Pasini, G. (2015). Primary insulin autoimmune syndrome in an Italian woman: a case report. Italian Journal of Medicine, 9(2), 169–172. https://doi.org/10.4081/itjm.2015.483

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