The management of the patient with headache: from evidence to clinical practice

  • Paola Gnerre | Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Ombretta Para Department of Internal Medicine, AOU Careggi, Firenze, Italy.
  • Francesco De Antoniis Emergency Department, Misericordia e Dolce Hospital, Prato, Italy.
  • Danilo Cavalieri Internal Medicine, Biomedical Campus, Roma, Italy.
  • Marianna Piombo Neurology, Biomedical Campus, Roma, Italy.


Headaches are the most prevalent neurological disorders and continue to be a frequent cause of Emergency Department use, accounting for 2% of all visits. Although it is a neurological disease it must be also a clinical competence of internist for its nature and frequency. The keys to effective management of these syndromes are differential diagnosis through history, physical examination, and diagnostic studies when necessary. This monograph highlights the importance of establishing whether headache is a secondary symptom of another disease process or a primary condition. The goal of headache management is for patients and healthcare professionals to work together to minimize pain and improve quality of life.


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headache, evidence-based recommendations, clinical approach.
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How to Cite
Gnerre, P., Para, O., De Antoniis, F., Cavalieri, D., & Piombo, M. (2015). The management of the patient with headache: from evidence to clinical practice. Italian Journal of Medicine, 9(1), 37-48.

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