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Italian Journal of Medicine

eISSN 1877-9352 - pISSN 1877-9344

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Editors-in-Chief: Francesco Dentali, Fulvio Pomero, Italy

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  • Genetic predictors of response to treatment of chronic hepatitis C virus infection in patients from southern Italy

    Mario Masarone, Roberta Russo, Antonella Gambale, Concetta Langella, Ferdinando Carlo Sasso, Luca Fontanella, Marco Romano, Achille Iolascon, Marcello Persico
    61-70
    27-02-2014
    https://doi.org/10.4081/itjm.2014.443
    2131
    PDF: 1538
    HTML: 592
  • Cytokine profile in COVID-19 infection: focus on interleukin-13, interleukin-33, and tumor necrosis factor-α as immunological markers

    Huda Saleem, Wafaa Hazim, Batool Mutar Mahdi, Mohammed S. Al-Iedani
    25-03-2025
    https://doi.org/10.4081/itjm.2025.1823
    941
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    SUPPLEMENTARY MATERIAL: 230
    HTML: 100
  • Characteristics, comorbidities and laboratory measures associated with disease severity and poor prognosis in young and elderly patients with COVID-19 admitted to medical wards in Emilia-Romagna region, Italy: a multicentre retrospective study

    Sirio Fiorino, Andrea Carusi, Alessandro Zappi, Fabio Tateo, Luca Peruzzo, Melissa Zanardi, Francesco Savelli, Giulia Di Marzio, Silvia Cesaretti, Francesca Dazzani, Raffaella Francesconi , Paolo Leandri , Gianfranco Tortorici , Susanna Vicari , Dora Melucci, Federico Lari
    21-06-2023
    https://doi.org/10.4081/itjm.2023.1608
    1793
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  • STAT3 eye-opener in COVID-19

    Chiara Mozzini, Giuseppe Lucchini, Mauro Pagani
    28-11-2023
    https://doi.org/10.4081/itjm.2023.1650
    1205
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    HTML: 65
  • Adult-onset Still’s disease with secondary macrophage activation syndrome: a case report

    Giuseppe Nicoletti, Antonio Bonelli, Rocco Clemente, Simona Ciuffreda, Gaetano Dentamaro, Agata Tiziana La Masa, Vito Lascaro, Pasquale Santarcangelo
    29-05-2023
    https://doi.org/10.4081/itjm.2023.1595
    1723
    PDF: 642
    HTML: 119
  • Interplay between lymphocyte subpopulation, inflammatory cytokines and their correlation with oxidative stress parameters in COVID-19

    Marija Petrusevska, Dragica Zendelovska, Emilija Atanasovska, Katerina Spasovska, Krsto Grozdanovski, Simona Stojanovska, Irina Panovska-Stavridis, Aleksandar Eftimov
    30-12-2022
    https://doi.org/10.4081/itjm.2022.1543
    1681
    PDF: 446
    HTML: 31
  • Diagnostic values of adenosine deaminase cytokines in fluid contributed to the detection of extrapulmonary tuberculosis

    Bui-Thi Thu Huong, Nguyen Minh Hien, Nguyen Tien Dung, Le-Thi Minh Hien, Luu Cong Thanh, Luu Vu Dung, Tran Khanh Chi, Nguyen-Van Khiem, Hoang Hai Yen
    22-10-2024
    https://doi.org/10.4081/itjm.2024.1810
    1014
    PDF: 493
    HTML: 14
  • Assessing tumor necrosis factor-α (-238 G/A and -308 G/A) genetic polymorphisms in sepsis susceptibility among cystic fibrosis patients

    Qahtan A. Mahdi, Jabbar S. Hassan, Abdulrhman M. Hassan Hadi, Ali Nayyef Umayra
    01-09-2025
    https://doi.org/10.4081/itjm.2025.2021
    431
    PDF: 283
    HTML: 39
  • Cytokine storm and colchicine potential role in fighting SARS-CoV-2 pneumonia

    Antonio Vitiello, Francesco Ferrara, Chiara Pelliccia, Giovanni Granata, Raffaele La Porta
    88-94
    29-04-2020
    https://doi.org/10.4081/itjm.2020.1284
    3065
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  • Screening of the key genes and signaling pathways for schizophrenia using bioinformatics and next generation sequencing data analysis

    Iranna Kotturshetti, Basavaraj Vastrad, Veena Kori, Chanabasayya Vastrad, Shivakumar Kotrashetti
    18-12-2024
    https://doi.org/10.4081/itjm.2024.1830
    3142
    PDF: 623
    SUPPLEMENTARY MATERIAL: 248
    HTML: 15
  • Identification of hub genes associated with hepatitis B virus-related hepatocellular cancer using weighted gene co-expression network analysis and protein-protein interaction network analysis

    Wenze Wu, Fang Lin, Zifan Chen, Kejia Wu, Changhuan Ma, Jing Zhuang, Donglin Sun, Qiang Zhu, Longqing Shi
    06-09-2023
    https://doi.org/10.4081/itjm.2023.1626
    1246
    PDF: 554
    HTML: 78
  • Metformin’s therapeutic potential in adenomyosis: insights from interleukin 8 level

    Damas Hendriansyah, Nusratuddin Abdullah, Rudy B. Leonardy, Mardiah Tahir, Samrichard Rambulangi, Firdaus Hamid
    22-04-2025
    https://doi.org/10.4081/itjm.2025.1940
    2095
    PDF: 600
    HTML: 0
  • Pathological changes of biochemical, hematological and coagulation analyses in patients with COVID-19 disease

    Zafer Gashi, Muhamet Kadrija
    22-04-2024
    https://doi.org/10.4081/itjm.2024.1723
    1361
    PDF: 552
    HTML: 75
  • Exploring some pro-inflammatory cytokines and adipokines as novel biomarkers in polycystic ovary syndrome

    Dlvin Akif Mustafa, Parween Abdulsamad Ismail
    11-09-2025
    https://doi.org/10.4081/itjm.2025.2023
    867
    PDF: 290
    SUPPLEMENTARY MATERIAL: 179
    HTML: 51
  • The role of bronchial washing of transforming growth factor β1 as a prognostic biomarker of advanced stages of non-small cell lung cancer

    Nur Afifah Thamrin, Arif Santoso, Sitti Nurisyah, Irawaty Djaharuddin, Harun Iskandar
    17-09-2025
    https://doi.org/10.4081/itjm.2025.2065
    745
    PDF: 149
    HTML: 0
  • Association of TNF-α, IFN-γ, IL-6, and IL-10 with different clinical manifestations of hepatitis B infection

    Mudathir Abdelshafea Abdelkareem Abakar, Ashwag Ali Hussein Ali, Eman Damra Ahmed Elhassan, Esra Ali Hamuda Altaher, Nosaiba Hussein Abdalbasit Musa, Shamsoun Khamis Kafi, Amira Eltom Fawzi Osman, Hisham Ali Waggiallah
    18-07-2023
    https://doi.org/10.4081/itjm.2023.1627
    1729
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  • Adult sickle cell disease and SARS-CoV-2: an increasingly common comorbidity for a rare disease

    Michaela Boggan, Christopher L. Edwards, Jordan Meek, Mary Wood, W. Jeff Bryson, John J. Sollers, Debra O. Parker, Camela S. Barker, Jessica Miller, Brianna Downey, Asha Lockett, Jazmin Rosales, Courtney Munroe, Jr., Noa Wax, Sharena Scott
    27-08-2024
    https://doi.org/10.4081/itjm.2024.1701
    875
    PDF: 541
    SUPPLEMENTARY MATERIAL: 248
    HTML: 55
  • Prolonged and biphasic acute hepatitis A in hepatitis B virus carrier

    Elena Garlatti Costa, Michela Ghersetti, Silvia Grazioli, Pietro Casarin
    241-244
    05-04-2016
    https://doi.org/10.4081/itjm.2016.571
    1605
    PDF: 1045
    HTML: 688
  • Pancreatic carcinoma development: new etiological and pathogenetic evidence

    Sirio Fiorino, Letizia Bacchi-Reggiani, Laura Pontoriero, Claudio Gallo, Elisabetta Chili, Michele Masetti, Nicola Zanini, Anna Grondona, Tania Silvestri, Gaia Deleonardi, Elisabetta Magrini, Roberto Motta, Adele Fornelli, Arrigo Bondi, Dario De Biase, Paola Baccarini, Giovanni Tallini, Antonio Tropeano, Andrea Cuppini, Gastone Castellani, Elio Jovine
    242-252
    17-12-2013
    https://doi.org/10.4081/itjm.2013.242
    2100
    PDF: 1190
    HTML: 222
  • Relationship of adiponectin levels with the severity of chronic obstructive pulmonary disease

    Rismawaty Samonding, Muh Ilyas, Bulkis Natsir, Irawaty Djaharuddin, Sitti Nurisyah, Erwin Arief
    22-12-2025
    https://doi.org/10.4081/itjm.2025.2015
    245
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  • Lung damages of malaria: a differential diagnosis and treatment in emergency room of a rare case

    Novella Carannante, Sabrina Scarica, Raffaele Disarno, Gerardo Langella, Pierpaolo Di Micco, Giuseppe Fiorentino
    29-11-2023
    https://doi.org/10.4081/itjm.2023.1603
    1311
    PDF: 728
    HTML: 2027
  • Primary pathologic role of interleukin-6 in rheumatoid arthritis

    G.L. Bajocchi, N. Pipitone, P.L. Boiardi, C. Salvarani
    40-46
    03-05-2013
    https://doi.org/10.4081/itjm.2008.4.40
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  • Smad2/3 signaling involved in urotensin II-induced phenotypic differentiation, collagen synthesis and migration of rat aortic adventitial fibroblasts

    Weizhao Lin, Xu Yang, Fan Zheng, Jianshe Yang, Yonggang Zhang
    30-08-2023
    https://doi.org/10.4081/itjm.2023.1637
    1051
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  • Hypereosinophilic syndromes

    Giuseppe Civardi, Luca Zanlari, Emanuele Bassi, Roberta Bonassi, Corrado Ajolfi
    129-135
    30-04-2013
    https://doi.org/10.4081/itjm.2009.129
    852
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  • Independent correlation between ischemia modified albumin and parathormone in hemodialysis patients

    Kenan Güçlü, Kağan Tur, Serdar Şahin, Aydın Güçlü
    30-12-2022
    https://doi.org/10.4081/itjm.2022.1560
    2548
    PDF: 504
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  • The impact of tocilizumab on hepatic enzyme levels in rheumatoid arthritis patients: a narrative review

    Rrezarta Alihajdaraj, Ergeta Ktona, Blerta Budani, Jehona Ismaili Kadriaj
    28-08-2025
    https://doi.org/10.4081/itjm.2025.2000
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    PDF: 342
    SUPPLEMENTARY MATERIAL: 108
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  • Adherence to interferon β treatment in Kosovan multiple sclerosis registry

    Blerim Myftiu, Edmond Komoni, Edita Malazogu, Fisnik Jashari, Shpresa Beqiri Rashiti, Melihate Pushka, Adnan Biqku, Syzana Aliçkaj Prebreza, Valbona Rrahmani Spanca, Jehona Rrustemi Bytyqi, Nexhmedin Shala, Afrim Blyta
    09-01-2024
    https://doi.org/10.4081/itjm.2024.1672
    1275
    PDF: 438
    HTML: 116
  • Epicardial fat, gender, and cardiovascular risk

    Manuel Monti, Roberto Marchetti, Giovanni Maria Vincentelli
    30-06-2021
    https://doi.org/10.4081/itjm.2021.1349
    1071
    PDF: 581
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  • The management of the patient with osteoporosis: from evidence to clinical practice

    Immacolata Ambrosino, Angela Riccardo, Paola Gnerre, Grace Massiah, Laura Castelnovo, Riccardo Muscariello, Marco Vacante
    253-266
    11-09-2017
    https://doi.org/10.4081/itjm.2017.784
    1949
    PDF: 905
    HTML: 692
  • New-onset type 1 diabetes mellitus triggered by SARS-CoV-2 infection in a patient with Hashimoto thyroiditis: a case report

    Elena Schipani, Andrea Cozzi, Giuseppe Salvatore Murgida, Valentina Francolini, Eleonora Sisti, Stefania Di Martino, Francesca Dainelli, Rosa Vecchio, Elisa Grifoni, Luca Masotti
    25-01-2021
    https://doi.org/10.4081/itjm.2021.1387
    1154
    PDF: 645
    HTML: 28
  • Macrophage activation syndrome: a lifetrheatening complication in a 44 year old woman

    Raffaele Natale, Annadora Morena, Clelia Nasti, Nicoletta Bertolini, Fabrizio Pasanisi, Lidia Santarpia
    20-06-2024
    https://doi.org/10.4081/itjm.2024.1752
    803
    PDF: 383
    HTML: 16
  • Potential role of vitamin D in prevention of skeletal and extraskeletal diseases in older people

    Andrea Montagnani, Roberto Nardi, Michela Cercignani, Valerio Verdiani
    29-35
    05-11-2015
    https://doi.org/10.4081/itjm.2015.597
    1838
    PDF: 1106
    HTML: 591
  • Pulmonary nodules in rheumatoid arthritis: the case of leflunomide

    Giovanni Simone Mancini, Silvia Rampini, Stefania Freguia, Clara Valsecchi, Domenico Cozzo, Anna Lou Christe, Adam Ogna
    07-05-2025
    https://doi.org/10.4081/itjm.2025.1964
    1108
    PDF: 321
    HTML: 89
  • The management of the patient with malnutrition: from evidence to clinical practice

    Maria Rita Poggiano, Sara Ciarla, Paola Gnerre, Anna Roberts, Laura Magni, Laura Morbidoni, Ada Maffettone, Antonella Paradiso, Massimo Rondana, Anna Maria Schimizzi, Roberto Risicato
    134-150
    14-06-2017
    https://doi.org/10.4081/itjm.2017.745
    3392
    PDF: 1534
    HTML: 2081
  • The role of adiponectin in diabetic retinopathy and insulin resistance

    Shahad Kh. Hameed, Rawaa F. Jawad, Haidar Ahmad Shamran
    07-10-2025
    https://doi.org/10.4081/itjm.2025.2049
    324
    PDF: 211
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  • Cardiovascular risk factors in sub-Saharan Africa: a review

    Manuel Monti, Maria Pia Ruggieri, Giovanni Maria Vincentelli, Fernando Capuano, Francesco Rocco Pugliese
    305-313
    19-05-2015
    https://doi.org/10.4081/itjm.2015.533
    3058
    PDF: 1370
    HTML: 1534
  • Serum interleukin-6 is associated with hypocalcemia, hypoferritinemia and hyperkalemia in end-stage renal disease patients

    Ghassaq T. Alubaidi, Yasameen A. Humadi , Dalyia A. Hamoodi, Hasanain Tuama Mahdi , Bushra Auid Anid, Ilham Ahmed Jasim, Ibrahim Mohammed Abdalfatah
    30-12-2022
    https://doi.org/10.4081/itjm.2022.1550
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  • The role of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in assessing hypothyroidism Hashimoto’s thyroiditis

    Ruqeya Murad, Ayman H. Alfeel, Zulekha Shemote, Praveen Kumar, Asaad Babker, Ahmed Luay Osman, Abdelgdair A. Altoum
    10-06-2025
    https://doi.org/10.4081/itjm.2025.1953
    1429
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  • An unusual Erdheim-Chester disease with orbital involvement: a case report

    Giuseppe Brunori, Aurelio Seidita, Lydia Giannitrapani, Antonietta Serruto, Francesco Bencivinni, Maurizio Soresi
    64-70
    29-11-2016
    https://doi.org/10.4081/itjm.2016.700
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  • Adipocytokines in metabolically healthy obesity

    Sofia G. Shulkina, Elena N. Smirnova, Maxim I. Yudin, Mikhail A. Osadchuk, Maxim V. Trushin
    169-175
    06-09-2019
    https://doi.org/10.4081/itjm.2019.1075
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  • Clinical factors affecting short- and long-term mortality in older patients with COVID-19: a retrospective cohort study

    Benedetta Pennella, Francesca Rotunno, Martina Mercuri, Marco Guerci, Mauro Molteni, Marta Biancucci, Clelia Berton, Francesca Troian, Paolo Maria Tripodi, Alessia Gilio, Antea Milano, Daniela Dalla Gasperina, Francesco Dentali, Aldo Bonaventura, Andrea Maria Maresca
    08-03-2024
    https://doi.org/10.4081/itjm.2024.1707
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    SUPPLEMENTARY MATERIAL: 134
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  • From Internal Wards to Intensive Care Units and backwards: the paths of the difficult patient

    Antonio Sacchetta, Alberto Da Rold, Samuele Guzzon, Diana Piccolo, Antonio Vendrame
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  • Present and future management of anti-neutrophil cytoplasmic antibody associated vasculitis: how therapy changed the prognosis

    Massimo L'Andolina, Giovanni Forte, Norma M. Marigliano, Salvatore Galasso, Francesca Mazzei, Domenico Galasso
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  • Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease

    Henshaw Uchechi Okoroiwu, Christopher Ogar Ogar
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  • Anticancer effects of punicalagin and 5-fluorouracil on laryngeal squamous cell carcinoma: an in vitro study

    Amany M. Taha, Eman Abd-Elshafy, Asmaa M. Khalifa, Najla Dar-Odeh, Shadia Elsayed, Daniah S. Alharkan, Aishah Alhodhodi, Ahmed Mohammed Sapri, Yassmeen SalahEldin Ragheb, Gihan A. Balbola
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  • Non-celiac gluten sensitivity: an emerging syndrome with many unsettled issues

    Umberto Volta, Giacomo Caio, Francesco Tovoli, Roberto De Giorgio
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  • From sciatica pain to a complex diagnosis: a case of pyomyositis and chronic lymphocytic leukemia

    Ottavia Magnani, Matteo Caiti, Elisabetta Cenni, Paolo Moscatelli
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  • Biomarkers for sepsis: past, present and future

    Giuseppe Chesi, Natale Vazzana, Claudio Giumelli
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  • Adult onset Still's disease presenting as fever of unknown origin: a case report with review of literature

    Harpreet Singh, Deepak Jain, Saroj Dhankhar, Rekha Mathur
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  • The great imitator

    Cristina Gozzi, Maurizio Tognetti, Lucio Brugioni
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  • The evolving role of selective internal radiation therapy in hepatocellular carcinoma

    Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Alessia Argenziano, Andrea Diglio, Angela Faggian
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  • Current challenges in COVID-19 diagnosis: a narrative review and implications for clinical practice

    Gabriella Nucera, Francesco Chirico, Valentina Raffaelli, Pietro Marino
    24-09-2021
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  • Fever and erythema: exclude all and then think of Still's disease!

    Marta Maset, Elena Garlatti Costa, Giorgio Siro Carniello, Silvia Grazioli, Michela Ghersetti, Pietro Casarin
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  • P89 | Macrophage activation syndrome secondary to salmonellosis E. Maccolini, E. Elia, A. Neri, D. Marini, C.E. Lizzio, L. Andreetto, L. Diotalevi, A. Trentini, M.C. Potenza, M. Migliori | Medicina Interna Migliori IRCCS Sant’Orsola, Bologna, Italy

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  • An elderly-onset rheumatic syndrome: is it RS3PE?

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  • Body mass index conditions and eating attitudes in young nurses: a pilot psycho-immune-endocrine investigation

    Yun-Chen Chang, Elsa Vitale
    24-10-2023
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  • Use of ursodeoxycholic acid in patients with hypertransaminasemia

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  • Unveiling silent threats: incidental diagnosis and conservative management of spontaneous isolated celiac artery dissection

    Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Andrea Diglio, Angela Faggian
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Keywords

  • Dislipidemie: la gestione internistica del paziente iperlipidemico
    467
  • Chronic asymptomatic hyperamylasemia unrelated to pancreatic disease
    282
  • Antimicrobial stewardship: un imperativo per il futuro
    264
  • Management of hypernatremias
    233
  • Hematologic emergencies
    210
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