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Italian Journal of Medicine

eISSN 1877-9352 - pISSN 1877-9344

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Editors-in-Chief: Francesco Dentali, Fulvio Pomero, Italy

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  • Genetic predictors of response to treatment of chronic hepatitis C virus infection in patients from southern Italy

    Mario Masarone, Roberta Russo, Antonella Gambale, Concetta Langella, Ferdinando Carlo Sasso, Luca Fontanella, Marco Romano, Achille Iolascon, Marcello Persico
    61-70
    27-02-2014
    https://doi.org/10.4081/itjm.2014.443
    2241
    Downloads: 1702
    HTML: 599
  • Cytokine profile in COVID-19 infection: focus on interleukin-13, interleukin-33, and tumor necrosis factor-α as immunological markers

    Huda Saleem, Wafaa Hazim, Batool Mutar Mahdi, Mohammed S. Al-Iedani
    25-03-2025
    https://doi.org/10.4081/itjm.2025.1823
    1238
    Downloads: 850
    HTML: 113
  • Characteristics, comorbidities and laboratory measures associated with disease severity and poor prognosis in young and elderly patients with COVID-19 admitted to medical wards in Emilia-Romagna region, Italy: a multicentre retrospective study

    Sirio Fiorino, Andrea Carusi, Alessandro Zappi, Fabio Tateo, Luca Peruzzo, Melissa Zanardi, Francesco Savelli, Giulia Di Marzio, Silvia Cesaretti, Francesca Dazzani, Raffaella Francesconi , Paolo Leandri , Gianfranco Tortorici , Susanna Vicari , Dora Melucci, Federico Lari
    21-06-2023
    https://doi.org/10.4081/itjm.2023.1608
    1984
    Downloads: 662
    HTML: 49
  • STAT3 eye-opener in COVID-19

    Chiara Mozzini, Giuseppe Lucchini, Mauro Pagani
    28-11-2023
    https://doi.org/10.4081/itjm.2023.1650
    1354
    Downloads: 602
    HTML: 76
  • Adult-onset Still’s disease with secondary macrophage activation syndrome: a case report

    Giuseppe Nicoletti, Antonio Bonelli, Rocco Clemente, Simona Ciuffreda, Gaetano Dentamaro, Agata Tiziana La Masa, Vito Lascaro, Pasquale Santarcangelo
    29-05-2023
    https://doi.org/10.4081/itjm.2023.1595
    1908
    Downloads: 795
    HTML: 175
  • Interplay between lymphocyte subpopulation, inflammatory cytokines and their correlation with oxidative stress parameters in COVID-19

    Marija Petrusevska, Dragica Zendelovska, Emilija Atanasovska, Katerina Spasovska, Krsto Grozdanovski, Simona Stojanovska, Irina Panovska-Stavridis, Aleksandar Eftimov
    30-12-2022
    https://doi.org/10.4081/itjm.2022.1543
    1836
    Downloads: 656
    HTML: 44
  • Diagnostic values of adenosine deaminase cytokines in fluid contributed to the detection of extrapulmonary tuberculosis

    Bui-Thi Thu Huong, Nguyen Minh Hien, Nguyen Tien Dung, Le-Thi Minh Hien, Luu Cong Thanh, Luu Vu Dung, Tran Khanh Chi, Nguyen-Van Khiem, Hoang Hai Yen
    22-10-2024
    https://doi.org/10.4081/itjm.2024.1810
    1519
    Downloads: 630
    HTML: 20
  • Assessing tumor necrosis factor-α (-238 G/A and -308 G/A) genetic polymorphisms in sepsis susceptibility among cystic fibrosis patients

    Qahtan A. Mahdi, Jabbar S. Hassan, Abdulrhman M. Hassan Hadi, Ali Nayyef Umayra
    01-09-2025
    https://doi.org/10.4081/itjm.2025.2021
    592
    Downloads: 402
    HTML: 45
  • Cytokine storm and colchicine potential role in fighting SARS-CoV-2 pneumonia

    Antonio Vitiello, Francesco Ferrara, Chiara Pelliccia, Giovanni Granata, Raffaele La Porta
    88-94
    29-04-2020
    https://doi.org/10.4081/itjm.2020.1284
    3220
    Downloads: 1844
    HTML: 189
  • Screening of the key genes and signaling pathways for schizophrenia using bioinformatics and next generation sequencing data analysis

    Iranna Kotturshetti, Basavaraj Vastrad, Veena Kori, Chanabasayya Vastrad, Shivakumar Kotrashetti
    18-12-2024
    https://doi.org/10.4081/itjm.2024.1830
    4288
    Downloads: 1109
    HTML: 17
  • Identification of hub genes associated with hepatitis B virus-related hepatocellular cancer using weighted gene co-expression network analysis and protein-protein interaction network analysis

    Wenze Wu, Fang Lin, Zifan Chen, Kejia Wu, Changhuan Ma, Jing Zhuang, Donglin Sun, Qiang Zhu, Longqing Shi
    06-09-2023
    https://doi.org/10.4081/itjm.2023.1626
    1403
    Downloads: 686
    HTML: 91
  • Metformin’s therapeutic potential in adenomyosis: insights from interleukin 8 level

    Damas Hendriansyah, Nusratuddin Abdullah, Rudy B. Leonardy, Mardiah Tahir, Samrichard Rambulangi, Firdaus Hamid
    22-04-2025
    https://doi.org/10.4081/itjm.2025.1940
    2758
    Downloads: 1384
    HTML: 3
  • Exploring some pro-inflammatory cytokines and adipokines as novel biomarkers in polycystic ovary syndrome

    Dlvin Akif Mustafa, Parween Abdulsamad Ismail
    11-09-2025
    https://doi.org/10.4081/itjm.2025.2023
    1163
    Downloads: 677
    HTML: 77
  • Pathological changes of biochemical, hematological and coagulation analyses in patients with COVID-19 disease

    Zafer Gashi, Muhamet Kadrija
    22-04-2024
    https://doi.org/10.4081/itjm.2024.1723
    1583
    Downloads: 641
    HTML: 77
  • The role of bronchial washing of transforming growth factor β1 as a prognostic biomarker of advanced stages of non-small cell lung cancer

    Nur Afifah Thamrin, Arif Santoso, Sitti Nurisyah, Irawaty Djaharuddin, Harun Iskandar
    17-09-2025
    https://doi.org/10.4081/itjm.2025.2065
    879
    Downloads: 533
    HTML: 1
  • Association of TNF-α, IFN-γ, IL-6, and IL-10 with different clinical manifestations of hepatitis B infection

    Mudathir Abdelshafea Abdelkareem Abakar, Ashwag Ali Hussein Ali, Eman Damra Ahmed Elhassan, Esra Ali Hamuda Altaher, Nosaiba Hussein Abdalbasit Musa, Shamsoun Khamis Kafi, Amira Eltom Fawzi Osman, Hisham Ali Waggiallah
    18-07-2023
    https://doi.org/10.4081/itjm.2023.1627
    2629
    Downloads: 853
    HTML: 97
  • Relationship of adiponectin levels with the severity of chronic obstructive pulmonary disease

    Rismawaty Samonding, Muh Ilyas, Bulkis Natsir, Irawaty Djaharuddin, Sitti Nurisyah, Erwin Arief
    22-12-2025
    https://doi.org/10.4081/itjm.2025.2015
    399
    Downloads: 372
    HTML: 2
  • Epicardial fat, gender, and cardiovascular risk

    Manuel Monti, Roberto Marchetti, Giovanni Maria Vincentelli
    30-06-2021
    https://doi.org/10.4081/itjm.2021.1349
    1177
    Downloads: 704
    HTML: 19
  • Adult sickle cell disease and SARS-CoV-2: an increasingly common comorbidity for a rare disease

    Michaela Boggan, Christopher L. Edwards, Jordan Meek, Mary Wood, W. Jeff Bryson, John J. Sollers, Debra O. Parker, Camela S. Barker, Jessica Miller, Brianna Downey, Asha Lockett, Jazmin Rosales, Courtney Munroe, Jr., Noa Wax, Sharena Scott
    27-08-2024
    https://doi.org/10.4081/itjm.2024.1701
    990
    Downloads: 1076
    HTML: 57
  • Lung damages of malaria: a differential diagnosis and treatment in emergency room of a rare case

    Novella Carannante, Sabrina Scarica, Raffaele Disarno, Gerardo Langella, Pierpaolo Di Micco, Giuseppe Fiorentino
    29-11-2023
    https://doi.org/10.4081/itjm.2023.1603
    1630
    Downloads: 884
    HTML: 2269
  • Primary pathologic role of interleukin-6 in rheumatoid arthritis

    G.L. Bajocchi, N. Pipitone, P.L. Boiardi, C. Salvarani
    40-46
    03-05-2013
    https://doi.org/10.4081/itjm.2008.4.40
    1244
    Downloads: 5441
  • Smad2/3 signaling involved in urotensin II-induced phenotypic differentiation, collagen synthesis and migration of rat aortic adventitial fibroblasts

    Weizhao Lin, Xu Yang, Fan Zheng, Jianshe Yang, Yonggang Zhang
    30-08-2023
    https://doi.org/10.4081/itjm.2023.1637
    1191
    Downloads: 634
    HTML: 53
  • Hypereosinophilic syndromes

    Giuseppe Civardi, Luca Zanlari, Emanuele Bassi, Roberta Bonassi, Corrado Ajolfi
    129-135
    30-04-2013
    https://doi.org/10.4081/itjm.2009.129
    908
    Downloads: 7482
  • The impact of tocilizumab on hepatic enzyme levels in rheumatoid arthritis patients: a narrative review

    Rrezarta Alihajdaraj, Ergeta Ktona, Blerta Budani, Jehona Ismaili Kadriaj
    28-08-2025
    https://doi.org/10.4081/itjm.2025.2000
    1705
    Downloads: 655
    HTML: 60
  • Pancreatic carcinoma development: new etiological and pathogenetic evidence

    Sirio Fiorino, Letizia Bacchi-Reggiani, Laura Pontoriero, Claudio Gallo, Elisabetta Chili, Michele Masetti, Nicola Zanini, Anna Grondona, Tania Silvestri, Gaia Deleonardi, Elisabetta Magrini, Roberto Motta, Adele Fornelli, Arrigo Bondi, Dario De Biase, Paola Baccarini, Giovanni Tallini, Antonio Tropeano, Andrea Cuppini, Gastone Castellani, Elio Jovine
    242-252
    17-12-2013
    https://doi.org/10.4081/itjm.2013.242
    2204
    Downloads: 1327
    HTML: 228
  • Independent correlation between ischemia modified albumin and parathormone in hemodialysis patients

    Kenan Güçlü, Kağan Tur, Serdar Şahin, Aydın Güçlü
    30-12-2022
    https://doi.org/10.4081/itjm.2022.1560
    2705
    Downloads: 643
    HTML: 50
  • Adherence to interferon β treatment in Kosovan multiple sclerosis registry

    Blerim Myftiu, Edmond Komoni, Edita Malazogu, Fisnik Jashari, Shpresa Beqiri Rashiti, Melihate Pushka, Adnan Biqku, Syzana Aliçkaj Prebreza, Valbona Rrahmani Spanca, Jehona Rrustemi Bytyqi, Nexhmedin Shala, Afrim Blyta
    09-01-2024
    https://doi.org/10.4081/itjm.2024.1672
    1416
    Downloads: 538
    HTML: 128
  • Prolonged and biphasic acute hepatitis A in hepatitis B virus carrier

    Elena Garlatti Costa, Michela Ghersetti, Silvia Grazioli, Pietro Casarin
    241-244
    05-04-2016
    https://doi.org/10.4081/itjm.2016.571
    1800
    Downloads: 1121
    HTML: 728
  • The management of the patient with osteoporosis: from evidence to clinical practice

    Immacolata Ambrosino, Angela Riccardo, Paola Gnerre, Grace Massiah, Laura Castelnovo, Riccardo Muscariello, Marco Vacante
    253-266
    11-09-2017
    https://doi.org/10.4081/itjm.2017.784
    2038
    Downloads: 1016
    HTML: 702
  • Body mass index conditions and eating attitudes in young nurses: a pilot psycho-immune-endocrine investigation

    Yun-Chen Chang, Elsa Vitale
    24-10-2023
    https://doi.org/10.4081/itjm.2023.1654
    2765
    Downloads: 866
    HTML: 49
  • Non-celiac gluten sensitivity: an emerging syndrome with many unsettled issues

    Umberto Volta, Giacomo Caio, Francesco Tovoli, Roberto De Giorgio
    225-231
    19-12-2013
    https://doi.org/10.4081/itjm.2013.461
    2404
    Downloads: 1843
    HTML: 365
  • Potential role of vitamin D in prevention of skeletal and extraskeletal diseases in older people

    Andrea Montagnani, Roberto Nardi, Michela Cercignani, Valerio Verdiani
    29-35
    05-11-2015
    https://doi.org/10.4081/itjm.2015.597
    1972
    Downloads: 1224
    HTML: 602
  • Pulmonary nodules in rheumatoid arthritis: the case of leflunomide

    Giovanni Simone Mancini, Silvia Rampini, Stefania Freguia, Clara Valsecchi, Domenico Cozzo, Anna Lou Christe, Adam Ogna
    07-05-2025
    https://doi.org/10.4081/itjm.2025.1964
    1352
    Downloads: 477
    HTML: 111
  • The management of the patient with malnutrition: from evidence to clinical practice

    Maria Rita Poggiano, Sara Ciarla, Paola Gnerre, Anna Roberts, Laura Magni, Laura Morbidoni, Ada Maffettone, Antonella Paradiso, Massimo Rondana, Anna Maria Schimizzi, Roberto Risicato
    134-150
    14-06-2017
    https://doi.org/10.4081/itjm.2017.745
    3564
    Downloads: 1704
    HTML: 2148
  • The role of adiponectin in diabetic retinopathy and insulin resistance

    Shahad Kh. Hameed, Rawaa F. Jawad, Haidar Ahmad Shamran
    07-10-2025
    https://doi.org/10.4081/itjm.2025.2049
    527
    Downloads: 381
    HTML: 31
  • New-onset type 1 diabetes mellitus triggered by SARS-CoV-2 infection in a patient with Hashimoto thyroiditis: a case report

    Elena Schipani, Andrea Cozzi, Giuseppe Salvatore Murgida, Valentina Francolini, Eleonora Sisti, Stefania Di Martino, Francesca Dainelli, Rosa Vecchio, Elisa Grifoni, Luca Masotti
    25-01-2021
    https://doi.org/10.4081/itjm.2021.1387
    1266
    Downloads: 772
    HTML: 30
  • Macrophage activation syndrome: a lifetrheatening complication in a 44 year old woman

    Raffaele Natale, Annadora Morena, Clelia Nasti, Nicoletta Bertolini, Fabrizio Pasanisi, Lidia Santarpia
    20-06-2024
    https://doi.org/10.4081/itjm.2024.1752
    971
    Downloads: 484
    HTML: 21
  • Cardiovascular risk factors in sub-Saharan Africa: a review

    Manuel Monti, Maria Pia Ruggieri, Giovanni Maria Vincentelli, Fernando Capuano, Francesco Rocco Pugliese
    305-313
    19-05-2015
    https://doi.org/10.4081/itjm.2015.533
    3169
    Downloads: 1534
    HTML: 1544
  • Efficacy of compression stockings on preventing post-thrombotic syndrome: a systematic review and meta-analysis of randomized controlled trials

    Mosaad Almegren
    16-04-2026
    https://doi.org/10.4081/itjm.2026.2463
    2251
    Downloads: 704
    HTML: 129
  • The role of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in assessing hypothyroidism Hashimoto’s thyroiditis

    Ruqeya Murad, Ayman H. Alfeel, Zulekha Shemote, Praveen Kumar, Asaad Babker, Ahmed Luay Osman, Abdelgdair A. Altoum
    10-06-2025
    https://doi.org/10.4081/itjm.2025.1953
    1644
    Downloads: 720
    HTML: 232
  • An unusual Erdheim-Chester disease with orbital involvement: a case report

    Giuseppe Brunori, Aurelio Seidita, Lydia Giannitrapani, Antonietta Serruto, Francesco Bencivinni, Maurizio Soresi
    64-70
    29-11-2016
    https://doi.org/10.4081/itjm.2016.700
    1986
    Downloads: 1677
    HTML: 739
  • Present and future management of anti-neutrophil cytoplasmic antibody associated vasculitis: how therapy changed the prognosis

    Massimo L'Andolina, Giovanni Forte, Norma M. Marigliano, Salvatore Galasso, Francesca Mazzei, Domenico Galasso
    14-25
    04-03-2013
    https://doi.org/10.4081/itjm.2013.14
    1295
    Downloads: 875
    HTML: 991
  • Lipoid pneumonia: a narrative review of recent developments

    Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Loredana Di Nuzzo, Michela Carfora, Luigi Coppola, Maria Cerrone, Teresa Argenziano, Alessia Argenziano, Andrea Diglio, Angela Faggian
    22-04-2026
    https://doi.org/10.4081/itjm.2026.2499
    1898
    Downloads: 518
    HTML: 129
  • Serum interleukin-6 is associated with hypocalcemia, hypoferritinemia and hyperkalemia in end-stage renal disease patients

    Ghassaq T. Alubaidi, Yasameen A. Humadi , Dalyia A. Hamoodi, Hasanain Tuama Mahdi , Bushra Auid Anid, Ilham Ahmed Jasim, Ibrahim Mohammed Abdalfatah
    30-12-2022
    https://doi.org/10.4081/itjm.2022.1550
    1884
    Downloads: 680
    HTML: 84
  • Adipocytokines in metabolically healthy obesity

    Sofia G. Shulkina, Elena N. Smirnova, Maxim I. Yudin, Mikhail A. Osadchuk, Maxim V. Trushin
    169-175
    06-09-2019
    https://doi.org/10.4081/itjm.2019.1075
    1895
    Downloads: 807
    HTML: 66
  • From Internal Wards to Intensive Care Units and backwards: the paths of the difficult patient

    Antonio Sacchetta, Alberto Da Rold, Samuele Guzzon, Diana Piccolo, Antonio Vendrame
    354-359
    15-12-2016
    https://doi.org/10.4081/itjm.2016.800
    1704
    Downloads: 1080
    HTML: 465
  • Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease

    Henshaw Uchechi Okoroiwu, Christopher Ogar Ogar
    10-14
    11-01-2018
    https://doi.org/10.4081/itjm.2018.918
    2210
    Downloads: 1063
    HTML: 717
  • Clinical factors affecting short- and long-term mortality in older patients with COVID-19: a retrospective cohort study

    Benedetta Pennella, Francesca Rotunno, Martina Mercuri, Marco Guerci, Mauro Molteni, Marta Biancucci, Clelia Berton, Francesca Troian, Paolo Maria Tripodi, Alessia Gilio, Antea Milano, Daniela Dalla Gasperina, Francesco Dentali, Aldo Bonaventura, Andrea Maria Maresca
    08-03-2024
    https://doi.org/10.4081/itjm.2024.1707
    1010
    Downloads: 749
    HTML: 22
  • Biomarkers for sepsis: past, present and future

    Giuseppe Chesi, Natale Vazzana, Claudio Giumelli
    301-307
    15-12-2016
    https://doi.org/10.4081/itjm.2016.795
    2835
    Downloads: 1356
    HTML: 1218
  • Adult onset Still's disease presenting as fever of unknown origin: a case report with review of literature

    Harpreet Singh, Deepak Jain, Saroj Dhankhar, Rekha Mathur
    388-392
    09-05-2017
    https://doi.org/10.4081/itjm.2017.824
    2371
    Downloads: 1171
    HTML: 760
  • Anticancer effects of punicalagin and 5-fluorouracil on laryngeal squamous cell carcinoma: an in vitro study

    Amany M. Taha, Eman Abd-Elshafy, Asmaa M. Khalifa, Najla Dar-Odeh, Shadia Elsayed, Daniah S. Alharkan, Aishah Alhodhodi, Ahmed Mohammed Sapri, Yassmeen SalahEldin Ragheb, Gihan A. Balbola
    22-02-2024
    https://doi.org/10.4081/itjm.2024.1699
    1676
    Downloads: 740
    HTML: 138
  • The great imitator

    Cristina Gozzi, Maurizio Tognetti, Lucio Brugioni
    189-192
    04-02-2014
    https://doi.org/10.4081/itjm.2014.430
    1722
    Downloads: 1229
    HTML: 354
  • The evolving role of selective internal radiation therapy in hepatocellular carcinoma

    Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Alessia Argenziano, Andrea Diglio, Angela Faggian
    15-01-2026
    https://doi.org/10.4081/itjm.2026.2414
    804
    Downloads: 493
    HTML: 2
  • From sciatica pain to a complex diagnosis: a case of pyomyositis and chronic lymphocytic leukemia

    Ottavia Magnani, Matteo Caiti, Elisabetta Cenni, Paolo Moscatelli
    24-09-2021
    https://doi.org/10.4081/itjm.2021.1386
    1493
    Downloads: 725
    HTML: 89
  • Fever and erythema: exclude all and then think of Still's disease!

    Marta Maset, Elena Garlatti Costa, Giorgio Siro Carniello, Silvia Grazioli, Michela Ghersetti, Pietro Casarin
    245-249
    05-04-2016
    https://doi.org/10.4081/itjm.2016.680
    1578
    Downloads: 1070
    HTML: 449
  • P89 | Macrophage activation syndrome secondary to salmonellosis E. Maccolini, E. Elia, A. Neri, D. Marini, C.E. Lizzio, L. Andreetto, L. Diotalevi, A. Trentini, M.C. Potenza, M. Migliori | Medicina Interna Migliori IRCCS Sant’Orsola, Bologna, Italy

    26-08-2025
    https://doi.org/10.4081/itjm.2025.2282
    208
  • An elderly-onset rheumatic syndrome: is it RS3PE?

    Marta Oliveira, Filipa Ferreira, Erica Ferreira, Rosa Jorge
    335-339
    11-09-2017
    https://doi.org/10.4081/itjm.2017.806
    2282
    Downloads: 1201
    HTML: 857
  • Use of ursodeoxycholic acid in patients with hypertransaminasemia

    Claudio Puoti, Maria Giuseppa Elmo
    141-147
    18-09-2014
    https://doi.org/10.4081/itjm.2014.426
    1830
    Downloads: 1359
    HTML: 1419
  • Unveiling silent threats: incidental diagnosis and conservative management of spontaneous isolated celiac artery dissection

    Guido Faggian, Roberto Faggian, Michela Salzano, Ciro Stavolo, Teresa Argenziano, Andrea Diglio, Angela Faggian
    20-01-2026
    https://doi.org/10.4081/itjm.2026.2385
    530
    Downloads: 401
    HTML: 24
  • Current challenges in COVID-19 diagnosis: a narrative review and implications for clinical practice

    Gabriella Nucera, Francesco Chirico, Valentina Raffaelli, Pietro Marino
    24-09-2021
    https://doi.org/10.4081/itjm.2021.1474
    1917
    Downloads: 1178
    HTML: 19
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Italian Journal of Medicine

is the official journal of the Federation of Associations of Hospital Doctors on Internal Medicine (FADOI) and it is published by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.

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