Differential diagnoses in COVID-19 pandemic: a retrospective descriptive study

Submitted: 26 October 2020
Accepted: 24 November 2020
Published: 23 December 2020
Abstract Views: 1209
PDF: 570
HTML: 17
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Since February 2020, severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection rapidly spread across Southern Switzerland. The available literature on differential diagnoses of coronavirus 2019 (COVID-19) is scarce. Our study aims to review differential diagnoses of SARS-CoV-2 infections in public hospitals in Southern Switzerland and describe patients' related outcomes. Between 01.03.2020 and 15.04.2020, 344 patients had a chest computed tomography-scan at admission, 210 of them were pathological. 172 patients had a positive nasopharyngeal swab for SARS-CoV-2, and 38 patients needed an additional diagnostic work-up and were included in this study. Among the selected patients, 8 underwent 2 polymerase chain reaction (PCR) for SARS-CoV-2, while 18 patients were subjected to 3 PCR. We observed 29 infective cases, 3 due to cardiovascular etiologies, 2 due to chronic obstructive pulmonary disease exacerbation, 1 due to cryptogenic organizing pneumonia, 3 not related to respiratory diseases. Our results highlight the importance of differential diagnosis in times of widespread occurrence of COVID-19, considering the similarity of symptoms and imaging appearance with other respiratory conditions.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Ufficio Federale della Sanità Pubblica. Press communication; 2020. Available from: https://www.bag.admin.ch/bag/it/home/das-bag/aktuell/medienmitteilungen.msg-id-78233.html Accessed: 23 August 2020.
COVID-19 information for Switzerland; 2020. Available from: https://www.corona-data.ch/ Accessed: 23 August 2020.
Rigamonti E, Salera D, Gheorghiu AC, Gianella P. The many faces of interstitial pneumonia: a case of presumed SARS-CoV-2 infection. Swiss Med Wkly 2020;150:w20312. DOI: https://doi.org/10.4414/smw.2020.20312
MacIntyre CR, Chughtai AA, Barnes M, et al. The role of pneumonia and secondary bacterial infection in fatal and serious outcomes of pandemic influenza a (H1N1). BMC Infect Dis 2018;18:637. DOI: https://doi.org/10.1186/s12879-018-3548-0
Houlihan CF, Patel S, Price DA, et al. A/N1N1 flu pandemic. Life threatening infections labelled swine flu. BMJ 2010;340:c137. DOI: https://doi.org/10.1136/bmj.c137
Arashiro T, Nakamura S, Asami T, et al. SARS-CoV-2 and Legionella Co-infection in a person returning from a Nile Cruise. J Travel Med 2020;27:taa053. DOI: https://doi.org/10.1093/jtm/taaa053
Li-Ru C, Zheng-Xin C, Yang-Chun L, et al. Pulmonary contusion mimicking COVID-19: a case-report. World J Clin Cases 2020;8:1554-60. DOI: https://doi.org/10.12998/wjcc.v8.i8.1554
Wei-Cai D, Han-Wen Z, Jaun Y, et al. CT imaging and differential diagnosis of COVID-19. Can Assoc Radiol J 2020;71:195-200. DOI: https://doi.org/10.1177/0846537120913033
Hani C, Trieu NH, Saab I, et al. COVID-19 pneumonia: a review of typical CT findings and differential diagnosis. Diagn Interv Imaging 2020;101:263-8. DOI: https://doi.org/10.1016/j.diii.2020.03.014
Bordi L, Nicastri E, Scorzolini L, et al. Differential diagnosis of illness in patients under investigation for the novel coronavirus (SARS-CoV-2) Italy February 2020. Euro Surveill 2020;25:pii=2000170. DOI: https://doi.org/10.2807/1560-7917.ES.2020.25.8.2000170
Colaneri M, Sacchi P, Zuccaro V, et al. Clinical characteristics of coronavirus disease (COVID-19) early findings from a teaching hospital in Pavia, North Italy, 21 to 28 February 2020. Euro Surveill 2020;25:pii=2000460. DOI: https://doi.org/10.2807/1560-7917.ES.2020.25.16.2000460

How to Cite

Rigamonti, E., Fusi-Schmidhauser, T., Argentieri, G., & Gianella, P. (2020). Differential diagnoses in COVID-19 pandemic: a retrospective descriptive study. Italian Journal of Medicine, 15(1). https://doi.org/10.4081/itjm.2020.1410

List of Cited By :

Crossref logo