Adult Swyer-James-MacLeod syndrome: report of two cases and review of the literature

Swyer-James-MacLeod syndrome is a rare clinico-pathological entity associated with post-infectious bronchiolitis obliterans occurring in childhood. It is characterized by hypoperfusion of pulmonary parenchyma resulting into a peculiar radiological pattern, such as a translucent or hyperlucent unilateral lung. Typically, this disorder is diagnosed in childhood during a workup for recurrent respiratory infections, but sometimes patients who have little or no sequelae bronchiectasis remain asymptomatic until adulthood, when diagnosis is made either incidentally or with symptoms. We present two cases of adult patients for whom diagnosis was made in the course of the workup for dyspnea.