P48 | Can glycemic monitoring through continuous glucose monitoring improve the management of the diabetic patient hospitalized for acute pathology in Internal Medicine? Evaluation from a department case study

M. Conti¹, G. Vella², M. Renda¹, R. Burlon¹, G. Cassataro¹, E. Fertitta¹, A. La Carrubba¹, M.G. Stella¹, L. Tomaiuolo¹, V. Volpe¹ | ¹Medicina Interna, Fondazione G. Giglio, Cefalù (PA), ²Università degli Studi di Palermo, Italy

Introduction: To compare diabetes metrics in patients hospitalized in Internal Medicine for acute respiratory or septic event between those who used traditional glycemic monitoring (DTX) or continuous glucose monitoring (CGM).
Methods: Retrospective study of a cohort of 180 patients hospitalized between April-December 2023, 90 of whom were monitored using CGM and comparison of their glycemic parameters with other 90 patients with a similar admission diagnosis who were monitored using DTX. In Dexcom group we evaluated mean glycemia (MBG), standard deviation (SD) of MBG, glycemic coefficient of variability (CV), time in range (TIR% 70-180 mg%), time above range (TAR% >180 mg%), time below range (TBR% <70 mg%). For DTX group we evaluated MBG as mean of daily glycemic values (on average 4,5 DTX samples/day), CV as SD/MBG, TIR as% of DTX values between 70-180 mg%, TAR as% of DTX >80 mg% and TBR as a% of DTX <70 mg%.
Results: Levene’s test suggested homogeneity of variances for most of the metrics, with p-values >0.05, indicative of no significant variability discrepancy, except for TBR. T-test unveiled substantial disparities between the groups: MBG demonstrated a significant mean difference (p <0.05), underscoring a substantial divergence in average blood glucose levels. Other parameters, including CV, TIR, and TAR, also manifested statistically significant differences.
Conclusion: Our experience highlights a significant difference in terms of glycemic metrics between patients monitored using CGM and those with DTX, the former improving TIR, TBR and CV.