Letters to the Editor
10 July 2024
Vol. 18 No. 3 (2024)
Age- and dose-independent adverse effect of venlafaxine-extended release on blood pressure: a case series of 13 normotensive psychiatric outpatients
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
7357
Views
519
Downloads
129
HTML
Authors
Dear Editor, the first antidepressant medication of the serotonin-norepinephrine reuptake inhibitor class is venlafaxine (effexor), which is taken orally with a half-life of 5 hours; however, its effective and chief metabolite (i.e., O-desmethylvenlafaxine) owns a half-life of 11 hours. [...]
Altmetrics
Downloads
Download data is not yet available.
Citations
Montastruc JL, Rousseau V, de Canecaude C, et al. Role of serotonin and norepinephrine transporters in antidepressant-induced arterial hypertension: a pharmacoepidemiological-pharmacodynamic study. Eur J Clin Pharmacol 2020;76:1321-7. DOI: https://doi.org/10.1007/s00228-020-02913-0
O’Donnell JM, Bies RR, Williams AJ. Drug therapy of depression and anxiety disorders. In: Brunton LL, Knollman BC. (eds). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics, 14th ed. McGraw-Hill Education, New York; 2023.
Wathra R, Mulsant BH, Thomson L, et al. Hypertension and orthostatic hypotension with venlafaxine treatment in depressed older adults. J Psychopharmacol 2020;34:1112-8. DOI: https://doi.org/10.1177/0269881120944154
Kıvrak Y, Güvenç TS, Akbulut N, et al. Accelerated hypertension after venlafaxine usage. Case Rep Psychiatry 2014:2014:659715. DOI: https://doi.org/10.1155/2014/659715
Humbert X, Fedrizzi S, Chrétien B, et al. Hypertension induced by serotonin reuptake inhibitors: analysis of two pharmacovigilance databases. Fundam Clin Pharmacol 2019;33:296-302. DOI: https://doi.org/10.1111/fcp.12440
How to Cite
Age- and dose-independent adverse effect of venlafaxine-extended release on blood pressure: a case series of 13 normotensive psychiatric outpatients. (2024). Italian Journal of Medicine, 18(3). https://doi.org/10.4081/itjm.2024.1758
Copyright (c) 2024 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.