https://doi.org/10.4081/itjm.2024.1696

Trabecular bone score in obese patients with and without diabetes

Vol. 18 No. 1 (2024)
Published: 5 February 2024
Obesity, diabetes, trabecular bone density
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Authors

Gordana Dzeletovic
gordanadzeletovic@gmail.com
Military Hospital, Novi Sad, Serbia.
Aleksandar Jovanovic
https://orcid.org/0000-0002-5461-4978
Faculty of Medicine, University of Pristina - Kosovska Mitrovica, Kosovo.
Tatjana Novakovic
https://orcid.org/0000-0001-7434-1877
Faculty of Medicine, University of Pristina - Kosovska Mitrovica, Kosovo.
Snezana Markovic-Jovanovic
https://orcid.org/0000-0003-3010-2668
Faculty of Medicine, University of Pristina - Kosovska Mitrovica, Kosovo.
Emilija Novakovic
https://orcid.org/0000-0001-8000-7955
Faculty of Medicine, University of Pristina - Kosovska Mitrovica, Kosovo.
Anja Dzeletovic
https://orcid.org/0009-0006-2866-832X
Faculty of Medicine, Novi Sad, Serbia.
Milena Lukić
Cord IPS, Novi Sad, Serbia.
Biljana Kostic-Inic
Clinical Hospital Centre, Pristina, Gračanica, Kosovo.
Sanja Jovanovic
https://orcid.org/0000-0001-5605-1083
Faculty of Medicine, University of Pristina - Kosovska Mitrovica, Kosovo.
Miljan Jankovic
https://orcid.org/0009-0003-3067-5340
Faculty of Medicine, University of Pristina - Kosovska Mitrovica, Kosovo.

The link between obesity, diabetes and bone metabolism is quite complex and not entirely clear. Although many clinical and epidemiological studies demonstrate that obesity enhances bone mineral density, its effect on bone microarchitecture is uncertain. The objective of this study was to examine the bone microarchitecture in obese patients with and without diabetes. The study included 119 individuals with ages from 30 to 50. Participants were divided into three groups: obese patients, obese diabetic patients, and a healthy control group. Results showed that obesity has a positive effect on trabecular bone score (TBS). Diabetes and obesity have a significant interactive impact on bone microarchitecture (TBS). Furthermore, HbA1c influences TBS in both obese diabetic patients and obese non-diabetic subjects. In contrast to the majority of studies, we found that obesity positively influenced TBS. TBS was inversely related to HbA1c levels in obese type 2 diabetics. Diabetes and obesity have a significant interactive impact on bone structure, in particular on bone microarchitecture.

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How to Cite

Dzeletovic, G., Jovanovic, A., Novakovic, T., Markovic-Jovanovic, S., Novakovic, E., Dzeletovic, A., Lukić, M., Kostic-Inic, B., Jovanovic, S., & Jankovic, M. (2024). Trabecular bone score in obese patients with and without diabetes. Italian Journal of Medicine, 18(1). https://doi.org/10.4081/itjm.2024.1696
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