https://doi.org/10.4081/itjm.2024.1683

Posterior circulation lesions are more frequently associated with early seizures after a stroke

Vol. 18 No. 1 (2024)
Published: 16 January 2024
Stroke, early seizures, posterior circulation stroke, NIHSS, ASPECT
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Authors

Argjend Shala
Clinic of Neurology, University Clinical Centre of Kosovo, Pristina; Department of Neurology, University of Prishtina, Pristina, Kosovo.
Afrim Blyta
Clinic of Neurology, University Clinical Centre of Kosovo, Pristina; Department of Neurology, University of Prishtina, Pristina, Kosovo.
Nexhmedin Shala
Clinic of Neurology, University Clinical Centre of Kosovo, Pristina; Department of Neurology, University of Prishtina, Pristina, Kosovo.
Dren Boshnjaku
https://orcid.org/0000-0002-2650-0332
Clinic of Neurology, University Clinical Centre of Kosovo, Pristina; Department of Neurology, University of Prishtina, Pristina, Kosovo.
Pranvera Ibrahimi
Clinic of Cardiology, University Clinical Center of Kosovo, Pristina, Kosovo; Department of Medical Sciences, UBT College, Pristina, Kosovo; Department of Clinical Medicine, Umeå University, Umeå, Sweden.
Fisnik Jashari
fisnik.jashari@uni-pr.edu
Department of Clinical Medicine, Umeå University, Umeå, Sweden; Clinic of Neurology, University Clinical Centre of Kosovo, Pristina; Department of Neurology, University of Prishtina, Pristina, Kosovo.

Early seizures (ES) following stroke are prevalent among the elderly population, representing the most common type of acquired seizures. This study aimed to determine the incidence of ES and investigate potential associations with various clinical and radiological factors. 260 stroke patients (mean age 72±13.2, 48.5% females) were prospectively enrolled and followed. Baseline demographic data, clinical data, stroke subtype, ES occurrence, National Institutes of Health Stroke Scale (NIHSS) scores, and Alberta Stroke Program Early CT Score (ASPECT) were collected and analyzed. ES was observed in 11.6% of patients with ischemic stroke compared to 7.1% among patients with hemorrhagic stroke. ES occurred more frequently in those with posterior circulation stroke (18.5% vs. 7.1%, P=0.008) and those with NIHSS >15 (19.4% vs. 8.4%, P=0.04). In a logistic regression analysis that adjusted for vascular risk factors and NIHSS, posterior circulation stroke remained significantly associated with ES, with an odds ratio of 3.14 (95% CI 1.20 to 7.73, P=0.012). This study revealed that ES following stroke is more common in patients with posterior circulation lesions. These findings emphasize the need for further investigation into additional factors that may influence ES occurrence and its impact on stroke management and patient outcomes.

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How to Cite

Shala, A., Blyta, A., Shala, N., Boshnjaku, D., Ibrahimi, P., & Jashari, F. (2024). Posterior circulation lesions are more frequently associated with early seizures after a stroke. Italian Journal of Medicine, 18(1). https://doi.org/10.4081/itjm.2024.1683
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