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Italian Journal of Medicine

eISSN 1877-9352 - pISSN 1877-9344

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Editor-in-Chief: Michele Meschi, Italy

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  • Urotensin II promotes the proliferation and secretion of vascular endothelial growth factor in rat dermal papilla cells by activating the Wnt-β-catenin signaling pathway

    Congjuan Liao, Zhen Huang, Liuting Chen, Xiaorong Fan, Jun Peng, Xiaoqing Tan, Jianshe Yang, Xusheng Zhang
    27-06-2023
    https://doi.org/10.4081/itjm.2023.1607
    1086
    PDF: 457
    HTML: 26
  • Adenoid ameloblastoma with dentinoid and cellular atypia: a rare case report

    Bacem A.E.O. Khalele, Rami A. Al-Shiaty
    238-240
    16-02-2016
    https://doi.org/10.4081/itjm.2016.639
    3438
    PDF: 1378
    HTML: 1074
  • Anticancer effects of punicalagin and 5-fluorouracil on laryngeal squamous cell carcinoma: an in vitro study

    Amany M. Taha, Eman Abd-Elshafy, Asmaa M. Khalifa, Najla Dar-Odeh, Shadia Elsayed, Daniah S. Alharkan, Aishah Alhodhodi, Ahmed Mohammed Sapri, Yassmeen SalahEldin Ragheb, Gihan A. Balbola
    22-02-2024
    https://doi.org/10.4081/itjm.2024.1699
    1388
    PDF: 558
    HTML: 116
  • Too many dangerous allergies

    Stefania Scarlini, Fabrizio Turrini, Antonella Caronna, Roberto Messora, Luca Sarti, Goretta Bonacorsi, Marco Bondi
    51-55
    25-10-2013
    https://doi.org/10.4081/itjm.2013.390
    1951
    PDF: 1021
    HTML: 347
  • Clinical significance of salivary, serum, nitric oxide, and arginase in breast cancer

    Araz M. Yousif, Parween A. Ismail
    30-12-2022
    https://doi.org/10.4081/itjm.2022.1553
    1115
    PDF: 425
    HTML: 97
  • Pancreatic carcinoma development: new etiological and pathogenetic evidence

    Sirio Fiorino, Letizia Bacchi-Reggiani, Laura Pontoriero, Claudio Gallo, Elisabetta Chili, Michele Masetti, Nicola Zanini, Anna Grondona, Tania Silvestri, Gaia Deleonardi, Elisabetta Magrini, Roberto Motta, Adele Fornelli, Arrigo Bondi, Dario De Biase, Paola Baccarini, Giovanni Tallini, Antonio Tropeano, Andrea Cuppini, Gastone Castellani, Elio Jovine
    242-252
    17-12-2013
    https://doi.org/10.4081/itjm.2013.242
    2000
    PDF: 1157
    HTML: 222
  • Smad2/3 signaling involved in urotensin II-induced phenotypic differentiation, collagen synthesis and migration of rat aortic adventitial fibroblasts

    Weizhao Lin, Xu Yang, Fan Zheng, Jianshe Yang, Yonggang Zhang
    30-08-2023
    https://doi.org/10.4081/itjm.2023.1637
    929
    PDF: 460
    HTML: 29
  • Folate deficiency and psycho-organic syndrome in elderly subjects: review of the literature

    Flavio Cursi
    116-125
    20-06-2018
    https://doi.org/10.4081/itjm.2018.958
    1768
    PDF: 876
    HTML: 294
  • Identification of hub genes associated with hepatitis B virus-related hepatocellular cancer using weighted gene co-expression network analysis and protein-protein interaction network analysis

    Wenze Wu, Fang Lin, Zifan Chen, Kejia Wu, Changhuan Ma, Jing Zhuang, Donglin Sun, Qiang Zhu, Longqing Shi
    06-09-2023
    https://doi.org/10.4081/itjm.2023.1626
    1074
    PDF: 479
    HTML: 74
  • Cardiovascular risk factors in sub-Saharan Africa: a review

    Manuel Monti, Maria Pia Ruggieri, Giovanni Maria Vincentelli, Fernando Capuano, Francesco Rocco Pugliese
    305-313
    19-05-2015
    https://doi.org/10.4081/itjm.2015.533
    2937
    PDF: 1303
    HTML: 1524
  • A 50-year-old man with desmoid-type fibromatosis of upper extremity

    Vitorino Modesto dos Santos, Viviane Vieira Passini Soares, Mayza Lemes Duarte, Priscilla Souza de Faria, Uadson Silva Barreto, Victor Manabu Yano
    403-406
    28-11-2017
    https://doi.org/10.4081/itjm.2017.859
    2069
    PDF: 640
    HTML: 382
  • Clinical case and short review of extreme short bowel syndrome: an update 21 years after

    Pasquale Mansueto, Aurelio Seidita, Salvatore Iacono, Antonio Carroccio
    45-51
    22-03-2016
    https://doi.org/10.4081/itjm.2016.543
    1876
    PDF: 1021
    HTML: 1293
  • Portal vein thrombosis and Budd-Chiari syndrome as onset of polycythemia vera

    Aurelio Seidita, Delia Sprini, Accursia Bongiovì, Tiziana Catalano, Filippo Barbiera, Maria Accardi, Pasquale Mansueto, Antonio Carroccio
    196-205
    19-09-2013
    https://doi.org/10.4081/itjm.2013.196
    1980
    PDF: 1239
    HTML: 1965
  • Management of celiac disease: from evidence to clinical practice

    Tiziana M. Attardo, Elena Magnani, Carlotta Casati, Danilo Cavalieri, Pietro Crispino, Federica Fascì Spurio, Stefano De Carli, Daniela Tirotta, Paola Gnerre
    345-359
    28-11-2017
    https://doi.org/10.4081/itjm.2017.821
    2054
    PDF: 928
    HTML: 631
  • The role of genetic variations in metabolic syndrome: insights into etiology, diagnosis, and management

    Darla Srinivasa Rao, Ajay Kumar, Shagun Agarwal, Rabab Hassan Elshaikh, AjabSingh Choudhary, Ranjay Kumar Choudhary, Assad M A Babker, Rohit Rathore, Zhannat Nurmakhanova, Zhanar Nurgaliyeva, Abdugani Musayev, Ashok Kumar Sah
    24-03-2025
    https://doi.org/10.4081/itjm.2025.1908
    1248
    PDF: 598
    HTML: 83
  • Primary pathologic role of interleukin-6 in rheumatoid arthritis

    G.L. Bajocchi, N. Pipitone, P.L. Boiardi, C. Salvarani
    40-46
    03-05-2013
    https://doi.org/10.4081/itjm.2008.4.40
    1125
    PDF: 4951
  • The management of the patient with malnutrition: from evidence to clinical practice

    Maria Rita Poggiano, Sara Ciarla, Paola Gnerre, Anna Roberts, Laura Magni, Laura Morbidoni, Ada Maffettone, Antonella Paradiso, Massimo Rondana, Anna Maria Schimizzi, Roberto Risicato
    134-150
    14-06-2017
    https://doi.org/10.4081/itjm.2017.745
    3254
    PDF: 1475
    HTML: 2049
  • Acute pneumonitis or vasculitis? A severe case with multiple organ involvement

    Balzarini Laura, Chiara Mancini, Mario Uccelli, Enrico Betri, Maurizio Marvisi
    367-369
    15-12-2015
    https://doi.org/10.4081/itjm.2015.572
    1357
    PDF: 892
    HTML: 763
  • The role of anagrelide in the treatment of essential thrombocytaemia

    Giuseppe Civardi, Luca Zanlari, Emanuele Bassi, Roberta Bonassi, Maurizio Marvisi
    41-46
    03-05-2013
    https://doi.org/10.4081/itjm.2008.2.41
    1002
    PDF: 1802
  • The myelodysplastic syndromes: diagnosis, prognosis and therapy

    Cristina Clissa, Carlo Finelli, Antonio de Vivo
    90-97
    07-03-2013
    https://doi.org/10.4081/itjm.2011.90
    1104
    PDF: 5147
  • Sex differences in adverse drug reaction and liver disease

    Ombretta Para, Pietro Crispino, Nunzia Barone, Sara Macis, Laura Airasca, Paola Gnerre, Cecilia Politi
    15-22
    20-03-2018
    https://doi.org/10.4081/itjm.2018.893
    2223
    PDF: 1003
    HTML: 494
  • The value of computed tomography perfusion for assessing the response of hepatocellular carcinoma to transarterial chemoembolization

    Bui Quang Huynh, Nguyen Duy Hung, Le Thanh Dung, Nguyen-Thi Thu, Nguyen-Thi Hai Anh, Ngo Quang Duy, Nguyen Minh Duc
    13-09-2024
    https://doi.org/10.4081/itjm.2024.1768
    746
    PDF: 444
    HTML: 47
  • Incidentally discovered pheochromocytoma and aldosterone-producing adenoma in the same adrenal gland

    Aurelio Negro, Rosaria Santi, Alessandro Giunta, Filippo Lococo, Giuseppe Gemelli, Simonetta Piana, Moira Ragazzi, Simonetta Cavalieri
    294-298
    22-09-2015
    https://doi.org/10.4081/itjm.2015.557
    1610
    PDF: 841
    HTML: 1161
  • Epidemiology of comorbidities in chronic obstructive pulmonary disease: clusters, phenotypes and outcomes

    Shambhu Aryala, Enrique Diaz-Guzmana, David M. Manninoa
    276-284
    10-12-2012
    https://doi.org/10.4081/itjm.2012.276
    835
    PDF: 1022
  • A rare case of multiple myeloma with several atypical manifestations

    Clelia Nasti, Raffaele Natale, Annadora Morena, Roberta Della Pepa, Fabrizio Pasanisi, Lidia Santarpia
    04-07-2024
    https://doi.org/10.4081/itjm.2024.1760
    2336
    PDF: 623
    HTML: 222
  • P113 | To connect the dots: the role of the internist in a case of immune deficiency D.P. Pallotta1, A. Granito1, A. Raiteri2, R. Neri2 | 1Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, 2Unità di Medicina Interna, Malattie Epatobiliari ed Immunoallergologiche, IRCCS AOU di Bologna, Italy

    27-08-2025
    https://doi.org/10.4081/itjm.2025.2308
    128
  • Sitagliptin versus saxagliptin in decompensated type 2 diabetes mellitus patients

    Antonio Asti, Alessandra D'Alessandro, Francesco Paolo Zito, Salvatore Nardi, Giovanni Sarnelli, Giorgio Maresca, Giuseppe D'Alessandro
    36-41
    22-03-2016
    https://doi.org/10.4081/itjm.2016.558
    5617
    PDF: 1145
    HTML: 7429
  • STAT3 eye-opener in COVID-19

    Chiara Mozzini, Giuseppe Lucchini, Mauro Pagani
    28-11-2023
    https://doi.org/10.4081/itjm.2023.1650
    1088
    PDF: 401
    HTML: 61
  • Is Rome ready to react to chemical, biological, radiological, nuclear, and explosive attacks? A tabletop simulation

    Francesco Rosiello, Antonio Vinci, Matteo Vitali, Manuel Monti, Lidia Ricci, Elisa D'oca, Felice Marco Damato, Virgilio Costanzo, Giovanni Ferrari, Matteo Ruggeri, Serafino Ricci
    14-05-2024
    https://doi.org/10.4081/itjm.2024.1731
    1180
    PDF: 421
    HTML: 92
  • Autoimmune liver diseases: internist's guide from bench to bedside

    Mario Visconti
    20-36
    20-03-2015
    https://doi.org/10.4081/itjm.2015.508
    1870
    PDF: 1192
    HTML: 2276
  • Epicardial fat, gender, and cardiovascular risk

    Manuel Monti, Roberto Marchetti, Giovanni Maria Vincentelli
    30-06-2021
    https://doi.org/10.4081/itjm.2021.1349
    989
    PDF: 506
    HTML: 12
  • Potential role of vitamin D in prevention of skeletal and extraskeletal diseases in older people

    Andrea Montagnani, Roberto Nardi, Michela Cercignani, Valerio Verdiani
    29-35
    05-11-2015
    https://doi.org/10.4081/itjm.2015.597
    1735
    PDF: 1066
    HTML: 586
  • Collecting clinical data during an emergency: quality of life in primary biliary cholangitis during the COVID-19 pandemic

    Marco Delle Monache, Marco Carli, Annarita Vestri, Lorenzo Nosotti, Teresa Morgillo, Michele Delle Monache
    26-09-2023
    https://doi.org/10.4081/itjm.2023.1609
    925
    PDF: 453
    HTML: 6
  • The effect of type 2 diabetes mellitus on clinical symptoms, sputum molecular test results, and lesions in thoracic photos of pulmonary tuberculosis patients

    Fikriatul Fadhilah, Erwin Arief, Nur Ahmad Tabri, Irawaty Djaharuddin, Arif Santoso, Jamaluddin Madolangan
    31-07-2025
    https://doi.org/10.4081/itjm.2025.2048
    544
    PDF: 194
    HTML: 0
  • Pathological changes of biochemical, hematological and coagulation analyses in patients with COVID-19 disease

    Zafer Gashi, Muhamet Kadrija
    22-04-2024
    https://doi.org/10.4081/itjm.2024.1723
    1225
    PDF: 504
    HTML: 75
  • A critical evaluation in the delivery of the ultrasound practice: the point of view of the radiologist

    Giovanni Stasi, Elsa M. Ruoti
    5-10
    20-03-2015
    https://doi.org/10.4081/itjm.2015.502
    4652
    PDF: 1434
    HTML: 1997
  • Platelet indices as prognostic markers in the critically ill patient

    Anusha J. Yadav, Shaikh Mohammed Aslam
    28-12-2020
    https://doi.org/10.4081/itjm.2020.1388
    1763
    PDF: 827
    HTML: 209
  • Immunohistochemical expression of transient receptor potential vanilloid 1 in World Health Organization grade IV astrocytoma, oral squamous cell carcinoma and bladder carcinoma

    Imrana Tanvir, Samina Qamar, Ahmad Alwazzan, Khurram Mehboob, Yousef Almehmadi, Ebtihal Ali Alharbi, Shadi Ahmed Alahmadi, Hafsa Adnan
    19-03-2025
    https://doi.org/10.4081/itjm.2025.1893
    701
    PDF: 472
    HTML: 99
  • Exploring some pro-inflammatory cytokines and adipokines as novel biomarkers in polycystic ovary syndrome

    Dlvin Akif Mustafa, Parween Abdulsamad Ismail
    11-09-2025
    https://doi.org/10.4081/itjm.2025.2023
    564
    PDF: 212
    SUPPLEMENTARY MATERIAL: 158
    HTML: 38
  • Sodium-glucose co-transporter-2 inhibitor-associated non-diabetic ketoacidosis: a case report

    Vincenzo Trapanese, Francesco Maruca, Maria Resilde Natale, Federica Giofrè, Francesca Cosentino, Silvia Sergi, Giuseppe Armentaro, Valentino Condoleo, Franco Arturi
    04-04-2024
    https://doi.org/10.4081/itjm.2024.1716
    1005
    PDF: 703
    HTML: 284
  • Non-surgical management of spontaneous splenic rupture in infectious mononucleosis

    Gerardo Dessì, Teseo Stefanini, Giovanni Berisso, Maja Ruff De Conti, Alessandra Centi, Marilisa Carrieri, Pradeep Sonwalkar
    193-195
    19-09-2014
    https://doi.org/10.4081/itjm.2014.455
    1751
    PDF: 927
    HTML: 626
  • Visceral leishmaniasis and lymphoma: a rare and dangerous couple

    Nicola Battino, Antonio Pisano
    10-03-2025
    https://doi.org/10.4081/itjm.2025.1843
    593
    PDF: 371
    HTML: 1
  • Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management

    Andrea Percivale, Paola Gnerre, Giulio Damonte, Sandra Buscaglia, Mario Monachesi, Lionello Parodi, Rodolfo Tassara, Gianluca Curletti, Giovanni Saccomani
    330-345
    15-12-2015
    https://doi.org/10.4081/itjm.2015.547
    4662
    PDF: 1317
    HTML: 4182
  • The impact of tocilizumab on hepatic enzyme levels in rheumatoid arthritis patients: a narrative review

    Rrezarta Alihajdaraj, Ergeta Ktona, Blerta Budani, Jehona Ismaili Kadriaj
    28-08-2025
    https://doi.org/10.4081/itjm.2025.2000
    443
    PDF: 250
    SUPPLEMENTARY MATERIAL: 72
    HTML: 37
  • An 81-year-old patient with recent diagnosis of classic testicular seminoma

    Sandro José Martins, José Carlos de Almeida, Vitorino Modesto dos Santos, Ana Carolina Vieira Cançado, Giovanna Ferraz Cavalcanti, Kelle Regina Alves Ribeiro
    143-146
    23-06-2016
    https://doi.org/10.4081/itjm.2016.603
    1545
    PDF: 933
    HTML: 914
  • Incidence and clinicopathological characteristics of breast cancer patients from a single center study

    Alaa Banjar
    29-10-2024
    https://doi.org/10.4081/itjm.2024.1820
    1779
    PDF: 542
    HTML: 132
  • Present and future management of anti-neutrophil cytoplasmic antibody associated vasculitis: how therapy changed the prognosis

    Massimo L'Andolina, Giovanni Forte, Norma M. Marigliano, Salvatore Galasso, Francesca Mazzei, Domenico Galasso
    14-25
    04-03-2013
    https://doi.org/10.4081/itjm.2013.14
    1147
    PDF: 748
    HTML: 980
  • Risk factors for colorectal cancer in Albania: a case-control study

    Marsela Sina, Skerdi Prifti, Adea Kocollari, Ilir Akshija, Dorina Osmanaj, Gentiana Qirjako
    21-07-2025
    https://doi.org/10.4081/itjm.2025.2007
    429
    PDF: 243
    HTML: 38
  • Agranulocytosis in a patient with acute Parvovirus B19 infection: a case study

    Carlo Di Donato, Monica Vecchi, Vincenzo Ferrari, Giampaolo Papi, Cristina Gozzi
    52-54
    22-03-2016
    https://doi.org/10.4081/itjm.2016.578
    1839
    PDF: 873
    HTML: 1062
  • Clostridioides difficile infection in hospital and community settings: summary document of a multidisciplinary group

    Anna Danise, Federica Furfaro, Gianni Gattuso, Nicola Lucio Liberato, Clara Mandelli, Giuseppe Mazzola, Bianca Osnaghi
    07-02-2024
    https://doi.org/10.4081/itjm.2024.1666
    2262
    PDF: 704
    HTML: 103
  • Adult onset Still's disease: a comparison of two clinical cases

    Livio Bonsignore, Roberto Cardillo, Salvatore Leotta, Sebastiano Pavone, Alfonsa Lucia Dimora, Irene Alfina Cavallaro, Rosaria Platania, Nunzio Maurizio Catania, Rocco Siciliano
    310-314
    17-12-2013
    https://doi.org/10.4081/itjm.2013.310
    1882
    PDF: 979
    HTML: 483
  • P120 | Tumourlets and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: a rare cause of Cushing syndrome D. Piazza, M. Parisotto, M. Parolin, A. Uliana, A. Lo Nigro, V. Benetton | Ospedale Ca’ Foncello, Treviso, Italy

    27-08-2025
    https://doi.org/10.4081/itjm.2025.2315
    85
  • Body mass index conditions and eating attitudes in young nurses: a pilot psycho-immune-endocrine investigation

    Yun-Chen Chang, Elsa Vitale
    24-10-2023
    https://doi.org/10.4081/itjm.2023.1654
    2453
    PDF: 535
    HTML: 36
  • Self-reported hypertension, dyslipidemia and hyperuricemia management by Italian Internal Medicine Units: a national survey of the FADOI Study Group in Cardiovascular Medicine

    Alberto Mazza, Salvatore Lenti, Maria D'Avino, Giuliano Pinna, Giancarlo Antonucci, Sara Ciarla, Fabrizio Colombo, Raffaele Costa, Susanna Cozzio, Alessandro De Palma, Erica Del Signore, Massimo Errico, Fabio Fiammengo, Giuseppe Iosa, Massimiliano Loreno, Federica Lorenzi, Rocco Paternò, Martino Pengo, Cecilia Politi, Marcello Rattazzi, Maurizio Renis, Flavio Tangianu, Nicola Tarquinio, Mario Trottini, Gianluigi Scannapieco, Giorgio Vescovo, Gualberto Gussoni, Mauro Campanini, Dario Manfellotto, Andrea Fontanella
    371-379
    28-11-2017
    https://doi.org/10.4081/itjm.2017.852
    1621
    PDF: 1341
    Appendix: 400
    HTML: 298
  • Proton pump inhibitors overuse: only inappropriate prescriptions or further iatrogenic damage?

    Mario Visconti
    217-228
    22-09-2015
    https://doi.org/10.4081/itjm.2015.562
    2837
    PDF: 1212
    HTML: 2221
  • From sciatica pain to a complex diagnosis: a case of pyomyositis and chronic lymphocytic leukemia

    Ottavia Magnani, Matteo Caiti, Elisabetta Cenni, Paolo Moscatelli
    24-09-2021
    https://doi.org/10.4081/itjm.2021.1386
    1295
    PDF: 563
    HTML: 58
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  • Assumption of drugs with self-injurer purpose: a retrospective study about 111 patients hospitalized in Policlinico of Modena
    470
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  • Retrieving the information stored in the donated organ may cause the patient’s personality to change after the transplant operation
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