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Italian Journal of Medicine

eISSN 1877-9352 - pISSN 1877-9344

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Editor-in-Chief: Michele Meschi, Italy

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  • Effects of the availability of new oral anticoagulants in patients with non-valvular atrial fibrillation in the real world: the NAIF study

    Francesco Ventrella, Franco Mastroianni, Sergio Cappello, Luigi Iamele, Samantha Errico, Massimo Errico
    176-183
    06-07-2016
    https://doi.org/10.4081/itjm.2016.715
    1501
    PDF: 954
    HTML: 342
  • A review on management of antiphospholipid syndrome in clinical practice

    Carmine Siniscalchi, Pietro Rossetti, Gaetano Carolla, Pierpaolo Di Micco, Adriano Stella, Michele Riva
    13-09-2023
    https://doi.org/10.4081/itjm.2023.1649
    2798
    PDF: 1148
    HTML: 82
  • Stroke prevention in atrial fibrillation: findings from Tuscan FADOI Stroke Registry

    Luca Masotti, Rinaldo Innocenti, Stefano Spolveri, Irene Chiti, Grazia Panigada, Cristiana Seravalle, Giancarlo Landini, Alberto Fortini, Rino Migliacci, Raffaele Laureano, for Tuscan FADOI Stroke Registry Investigators
    134-140
    12-06-2014
    https://doi.org/10.4081/itjm.2014.450
    1639
    PDF: 1271
    Appendix: 582
    HTML: 622
  • oral anticoagulants, emergency treatment.

    Emergency management of patients being treated with oral anticoagulants

    Franco Manzato, Massimo Franchini
    234-241
    17-12-2013
    https://doi.org/10.4081/itjm.2013.234
    1117
    PDF: 886
    HTML: 305
  • D-dimer: a useful tool in gauging optimal duration of oral anticoagulant therapy?

    M. Silingardi, A. Pizzini, I. Iori
    45-47
    03-05-2013
    https://doi.org/10.4081/itjm.2007.2.45
    1057
    PDF: 2415
  • Pregnancy and heart disease: what Internists should know

    Riccardo Gerloni, Domenico Panuccio
    288-304
    11-09-2017
    https://doi.org/10.4081/itjm.2017.815
    1448
    PDF: 730
    HTML: 270
  • Assessment and predictors of inappropriate dose of direct oral anticoagulants

    Mosaad O. Almegren
    09-01-2024
    https://doi.org/10.4081/itjm.2024.1679
    995
    pdf: 501
    HTML: 139
  • Patent foramen ovale and ischemic stroke: more shadows than lights? What the internist should know

    Andrea Donti
    175-184
    30-09-2016
    https://doi.org/10.4081/itjm.2016.676
    1634
    PDF: 979
    HTML: 924
  • Old and new oral anticoagulants for secondary stroke prevention in atrial fibrillation

    Tommaso Sacquegna, Anna Zaniboni, Andrea Rubboli, Gaetano Procaccianti, Michela Crisci, Fabiola Maioli, Giorgia Arnone, Giuseppe Di Pasquale
    314-322
    15-12-2015
    https://doi.org/10.4081/itjm.2015.468
    1999
    PDF: 944
    HTML: 1241
  • The incidence of bleeding in patients with nonvalvular atrial fibrillation using anticoagulants: a real-world report with the biggest Vietnamese data

    Bui The Dung, Cao Ngoc Mai Han, Tran Hoa, Nguyen Thanh Hien
    17-02-2025
    https://doi.org/10.4081/itjm.2025.1807
    2031
    PDF: 392
    HTML: 1
  • How artificial intelligence during the pandemic modified the role of a biomarker as d-dimer

    Pierpaolo Di Micco, Francesca Futura Bernardi, Giovanni Maria Fusco, Alessandro Perrella
    20-11-2023
    https://doi.org/10.4081/itjm.2023.1656
    1058
    PDF: 385
    HTML: 30
  • A young woman with headache and seizures

    A.M. Pizzini, M. Silingardi, I. Iori
    25-29
    03-05-2013
    https://doi.org/10.4081/itjm.2008.4.25
    950
    PDF: 3814
  • Segmental arterial mediolysis: a challenging diagnosis in internal medicine

    Giulia Bombardieri, Alessandra Rustici, Michele Caselli, Chiara Chirico, Veronica Bocchi, Andrea Montagnani
    27-09-2024
    https://doi.org/10.4081/itjm.2024.1795
    637
    PDF: 277
    HTML: 152
  • The treatment of venous thromboembolism with new oral anticoagulants

    Davide Imberti
    29-35
    24-12-2013
    https://doi.org/10.4081/itjm.2013.s8.29
    1101
    PDF: 876
  • Hemorrhagic complications in COVID-19: three women with pectoral hematoma and a review

    Barbara Presciuttini, Dario Benazzi, Massimo Amato, Mauro Pagani
    04-07-2023
    https://doi.org/10.4081/itjm.2023.1590
    1070
    PDF: 345
    HTML: 26
  • Asymptomatic superior mesenteric vein thrombosis as unusual complication of acute cytomegalovirus infection: a case report

    Michele Bertoni, Filippo Risaliti, Alessandra Giani, Emanuele Calabrese, Massimo Edoardo Di Natale
    147-150
    05-10-2015
    https://doi.org/10.4081/itjm.2015.596
    1607
    PDF: 900
    HTML: 465
  • Characteristics and clinical management of acute pulmonary embolism in real world: findings from TUSCAN-PE study

    Luca Masotti, Filippo Pieralli, Grazia Panigada, Francesco Corradi, Rino Migliacci, Salvatore Lenti, Alessandro Tafi, Carlo Nozzoli, Giancarlo Landini, for TUSCAN-PE Investigators
    125-133
    03-06-2014
    https://doi.org/10.4081/itjm.2014.504
    2154
    PDF: 1382
    Appendix: 1110
    HTML: 757
  • Optimal duration of anticoagulant therapy in patients with venous thromboembolism

    Gualtiero Palareti
    235-244
    14-09-2018
    https://doi.org/10.4081/itjm.2018.1077
    1546
    PDF: 1811
    HTML: 260
  • Isolated dissection of the superior mesenteric artery: a case report and literature review

    Aurelio Seidita, Filippo Barbiera, Elena Murmura, Maria Accardi, Alberto D'Alcamo, Giusi Randazzo, Pasquale Mansueto, Antonio Carroccio, Delia Sprini
    56-63
    30-10-2013
    https://doi.org/10.4081/itjm.2013.168
    6522
    PDF: 1052
    HTML: 1653
  • How to manage new oral anticoagulants in case of surgery

    Davide Imberti
    36-40
    24-12-2013
    https://doi.org/10.4081/itjm.2013.s8.36
    954
    PDF: 850
  • Sex-gender and atrial fibrillation treatment in the AntiThrombotic Agents in Atrial Fibrillation (ATA-AF) study

    Cecilia Politi, Tiziana Ciarambino, Letizia Riva, Stefania Frasson, Donata Lucci, Gualberto Gussoni, Lucio Gonzini, Mauro Campanini, Michele Gulizia, Giuseppe Di Pasquale, Giovanni Mathieu, on behalf of ATA-AF Steering Committee and Investigators
    207-212
    16-02-2016
    https://doi.org/10.4081/itjm.2016.649
    1759
    PDF: 1483
    Appendix: 707
    HTML: 544
  • SERAFINO MANSUETO AWARD | Low-density lipoprotein cholesterol levels and bleeding during anticoagulation for venous hromboembolism C. Siniscalchi1, T. Meschi1, P. Di Micco2, E. Imbalzano3, L. Hernandez-Blasco4, J.L. Fernandez-Reyes5, A. Garcia-Ortega6, P. Verhamme7, J. Alfonso-Megido8, M. Monreal9 | 1Department of Internal Medicine, Parma University Hospital, Parma, Italy; 2AFO Medicina PO Santa Maria delle Grazie, Pozzuoli Naples Hospital 2 Nord; Naples, Italy; 3Division of Internal Medicine, Department of Clinical and Experimental Medicine, University of Messina, Italy; 4Pneumology Department of Clinical Medicine, Miguel Hernández University, ISABIAL, Dr. Balmis University General Hospital, Alicante, Spain; 5Department of Internal Medicine, Complejo Hospitalario de Jaén, Spain; 6Department of Pneumonology, Hospital Universitario Doctor Peset, Valencia, Spain; 7Vascular Medicine and Haemostasis, University of Leuven, Belgium; 8Hospital Valle del Nalón, Department of Internal Medicine, Langreo, Asturias, Spain; 9Chair for the Study of Thromboembolic Disease, Faculty of Health Sciences, UCAM, Universidad Católica San Antonio de Murcia, Spain. CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain

    25-08-2025
    https://doi.org/10.4081/itjm.2025.2151
    73
  • Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease

    Henshaw Uchechi Okoroiwu, Christopher Ogar Ogar
    10-14
    11-01-2018
    https://doi.org/10.4081/itjm.2018.918
    1720
    PDF: 801
    HTML: 661
  • Liver diseases and pregnancy

    Pietro Crispino, Luca Fontanella, Paola Gnerre
    278-287
    11-09-2017
    https://doi.org/10.4081/itjm.2017.817
    1571
    PDF: 813
    HTML: 302
  • Multi-professional audit supports clinical governance in projecting and implementing a new stroke care area

    Marco Masina, Simona Malservisi, Elisabetta Domenichini, Pio Francesco Censoni, Nadia Mingolini
    56-63
    04-03-2013
    https://doi.org/10.4081/itjm.2013.56
    1291
    PDF: 714
    HTML: 459
  • Anticoagulation in the early phase of non-valvular atrial fibrillation-related acute ischemic stroke: where do we stand?

    Luca Masotti, Elisa Grifoni, Alessandro Dei, Vieri Vannucchi, Federico Moroni, Grazia Panigada, Stefano Spolveri, Giancarlo Landini
    24-31
    03-01-2019
    https://doi.org/10.4081/itjm.2019.1111
    1417
    PDF: 807
    HTML: 71
  • Minimally invasive versus median sternotomy for mechanical mitral valve replacement: a single-center comparative study of treatment outcomes and quality of life

    The Binh Nguyen, Tran-Thuy Nguyen, Long Hoang Luong, Duc Hoang Nguyen, Cong Huu Nguyen, Ngoc Thanh Le, Bao Giang Kim
    12-06-2025
    https://doi.org/10.4081/itjm.2025.1963
    946
    PDF: 231
    HTML: 0
  • Cryptogenic stroke

    Michele Stornello, Roberto Cappellani, Giuseppe Micieli, Simona Sacco, Stefano Spolveri, Roberto Sterzi, Danilo Toni, Antonio Carolei
    185-194
    30-09-2016
    https://doi.org/10.4081/itjm.2016.682
    1966
    PDF: 1179
    HTML: 590
  • Young FADOI and gender medicine: sex gender differences in cardiovascular disease

    Tiziana Ciarambino, Miriam Gino, Paola Gnerre, Elena Barbagelata, Nunzia Barone, Francesca Saladini, Federica Lorenzi, Marta Zanon, Maria Cristina Pasquini, Cecilia Politi
    23-31
    20-03-2018
    https://doi.org/10.4081/itjm.2018.864
    2735
    PDF: 1163
    HTML: 482
  • Nattokinase historical sketch on experimental and clinical evidence

    Pierpaolo Di Micco, Francesca Futura Bernardi, Giuseppe Camporese, Mario Biglietto, Alessandro Perrella, Tiziana Ciarambino, Vincenzo Russo, Egidio Imbalzano
    16-05-2023
    https://doi.org/10.4081/itjm.2023.1583
    1854
    PDF: 656
    HTML: 653
  • A rare cause of pulmonary embolism: the popliteal vein aneurysm

    V. Manno, N. Cardona, L. Pilegi
    40-44
    03-05-2013
    https://doi.org/10.4081/itjm.2007.2.40
    1125
    PDF: 1396
  • CO26 | Direct oral anticoagulants for the treatment of venous thromboembolism in patients with cancer: a FADOI survey among Campanian Internal Medicine wards E. Marrone1, C. Arturo2, F. Cannavacciuolo3, D. D’Ambrosio4, F. Gallucci1, M. Amitrano3, C. Di Gennaro2, P. Morella1, A. Maffettone5 | 1UOC Medicina 3, AORN A Cardarelli, Napoli, 2UOC Medicina Generale, PO A. Rizzoli, Ischia (NA), 3UOC Medicina Interna, AO Moscati, Avellino, 4UOC Medicina Generale, PO Aversa (CE), 5UOC Medicina ad indirizzo cardiovascolare e dismetabolico AORN dei Colli, Ospedale Monaldi, Italy

    25-08-2025
    https://doi.org/10.4081/itjm.2025.2178
    56
  • A young woman with a left thoracic pain and normal chest radiograph

    Vitorino Modesto dos Santos, Christiane Aires Teixeira, Ana Carla Andrade de Almeida, Giovana Ferraz Cavalcanti, Tereza Cristina Batista da Mota, Ana Carolina Vieira Cançado
    74-76
    27-10-2015
    https://doi.org/10.4081/itjm.2015.644
    1456
    PDF: 849
    HTML: 381
  • Management of major bleeding in patients treated with direct oral anticoagulants: from experience to standardized protocols

    Sara Mascia, Anna Maria Ferrari, Nicola Macarone Palmieri, Elisa Romagnoli, Chiara Catena, Serena Scarabottini, Francesca Mori, Lucio Brugioni
    43-48
    17-06-2020
    https://doi.org/10.4081/itjm.2020.1224
    980
    PDF: 650
    HTML: 212
  • The management of the patient with non-variceal upper gastrointestinal bleeding: from evidence to clinical practice

    Maddalena Zippi, Mariella Frualdo, Luciano Mucci, Marta Zanon, Chiara Marzano, Claudio Cassieri, Paola Gnerre, Pietro Crispino
    246-252
    27-12-2016
    https://doi.org/10.4081/itjm.2016.713
    1473
    PDF: 1000
    HTML: 291
  • Retrospective analysis on clinical characteristics and venous thromboembolism outcomes using bridging prophylaxis with low molecular weight heparin for thrombophilic women performing oocyte retrieval for assisted reproductive procedures: 15 years of experience

    Pierpaolo Di Micco, Corrado Lodigiani, Lidia Luciana Rota, Giuseppe Camporese, Ida Strina, Carlo Alviggi
    17-06-2024
    https://doi.org/10.4081/itjm.2024.1749
    573
    PDF: 376
    HTML: 32
  • The unseen connection: laryngeal carcinoma and thrombosis of the internal jugular vein

    Laura Leci-Tahiri, Lisa Tahiri, Valbona Zhjeqi, Emina Ramku
    17-02-2025
    https://doi.org/10.4081/itjm.2025.1882
    1843
    PDF: 314
    HTML: 122
  • Cryptogenic strokes and embolic strokes of unknown source: lights and shadows of a new construct

    Marco Masina
    171-174
    30-09-2016
    https://doi.org/10.4081/itjm.2016.720
    1453
    PDF: 918
    HTML: 635
  • Management of sepsis: from evidence to clinical practice

    Riccardo Gerloni, Luciano Mucci, Carlotta Casati, Andrea Crociani, Ombretta Para, Elisabetta Benetti, Paola Gnerre, Anna Bovero, Elisa Romagnoli, Nicola Tarquinio, Clelia Canale, Davide Brancato, Laura Massarelli, Salvatora Piras
    308-328
    15-12-2016
    https://doi.org/10.4081/itjm.2016.796
    3336
    PDF: 1438
    Appendix: 607
    HTML: 1502
  • Pathological changes of biochemical, hematological and coagulation analyses in patients with COVID-19 disease

    Zafer Gashi, Muhamet Kadrija
    22-04-2024
    https://doi.org/10.4081/itjm.2024.1723
    1105
    PDF: 431
    HTML: 75
  • Multiple contemporary arterial dissection in Ehlers-Danlos syndrome type IV

    Anna Rocci, Enrico Paganelli, Angelo Rossetti, Carla Marcato, Davide Martorana, Maria Ilaria Tassoni, Roberto Quintavalla
    77-81
    20-03-2015
    https://doi.org/10.4081/itjm.2015.494
    2040
    PDF: 1142
    HTML: 890
  • An uncommon case of postpartum venous thrombosis in a patient with hereditary angioedema. Patient from the ITACA Cohort (Italian Network for Hereditary and Acquired Angioedema)

    Francesco Giardino, Andrea Caruso, Simone Giosuè Longhitano, Lorena Domenica Campanello
    19-11-2024
    https://doi.org/10.4081/itjm.2024.1836
    1048
    PDF: 425
    HTML: 104
  • Myocardial contrast echocardiography in the diagnosis of a left ventricular hemangioma

    Kyriacos Papadopoulos, Constantinos Makrides
    151-153
    23-06-2016
    https://doi.org/10.4081/itjm.2016.618
    1160
    PDF: 717
    Video 1: 603
    Video 2: 502
    HTML: 519
  • Gender differences in ischemic stroke intra-hospital mortality: a systematic review

    Tiziana Ciarambino, Orazio Valerio Giannico, Amalia Campanile, Antonella Fischetti, Elena Barabgelata, Imma Ambrosino, Ombretta Para, Cecilia Politi, Mauro Giordano
    30-06-2021
    https://doi.org/10.4081/itjm.2021.1378
    995
    PDF: 464
    HTML: 44
  • New antibiotic development: barriers and opportunities

    Ercole Concia, Fulvia Mazzaferri, Maddalena Cordioli
    255-271
    15-12-2016
    https://doi.org/10.4081/itjm.2016.790
    3368
    PDF: 1815
    HTML: 1988
  • Clinical utility of echocardiography in internal medicine: a narrative review

    Nicola Mumoli, Stefania Marengo
    06-11-2024
    https://doi.org/10.4081/itjm.2024.1802
    1968
    PDF: 635
    HTML: 128
  • Thrombophilias: therapeutic employment of direct oral anticoagulants in venous hypercoagulable states

    Federico Cacciapuoti
    136-142
    17-09-2020
    https://doi.org/10.4081/itjm.2020.1296
    855
    PDF: 565
    HTML: 361
  • P51 | Unilateral internal jugular vein thrombosis as presentation of malignancy: case report L. Criscuolo1, R. Ruocco2, A. Villani2, M. Del Core2, R. Epifani3, J.G. Di Salvo4, R. Ranieri5, C. Ricozzi5, A. Padula5, K. Gjeloshi5 | 1OORR Area Stabiese, Castellammare di Stabia (NA), 2Università degli Studi della Campania Luigi Vanvitelli, Napoli, 3Azienda Ospedaliera dei Colli - CTO, Napoli, 4Ospedale Santa Maria della Pietà, Nola (NA), 5Azienda Ospedaliera Universitaria, Napoli, Italy

    26-08-2025
    https://doi.org/10.4081/itjm.2025.2244
    36
  • Giant aneurysm of circumflex coronary artery in asymptomatic patient

    Angelo Bosio, Ottavio Pallisco, Gabriele Monaco, Paolo Fornengo, Claudia De Feo, Andrea Corgnier, Guido Ferretti, Giacomo Boccuzzi, Giacomo Paolo Vaudano, Claudio Pascale
    234-237
    05-04-2016
    https://doi.org/10.4081/itjm.2016.683
    1397
    PDF: 823
    HTML: 426
  • P79 | Subclinical atrial fibrillation in embolic stroke of undetermined source: management and stroke recurrence E. Grifoni, A. Baglini, I. Sivieri, M. Mannini, G. Iandoli, V. Vescera, E. Giglio, E. Brai, E. Cosentino, L. Masotti | Medicina Interna 2, Ospedale San Giuseppe, Empoli, Italy

    26-08-2025
    https://doi.org/10.4081/itjm.2025.2272
    38
  • Prevalence and determinants of permanent atrial fibrillation in post-menopausal hypertensive women

    Maria Maiello, Annagrazia Cecere, Marco Matteo Ciccone, Pasquale Palmiero
    02-10-2023
    https://doi.org/10.4081/itjm.2023.1652
    602
    PDF: 262
    HTML: 1
  • Approach to leg edema

    Fulvio Pomero, Roberta Re, Michele Meschi, Domenico Montemurro, Laura Spadafora, Valentina Borretta, Monica Zampogna, Annalisa Marchetti, Mariangela Di Lillo, Daniela Tirotta, Chiara Bozzano, Micaela La Regina, Paola Gnerre
    267-277
    11-09-2017
    https://doi.org/10.4081/itjm.2017.771
    4109
    PDF: 1914
    HTML: 4798
  • Acetylsalicylic acid in primary prevention: a review

    Mauro Campanini, Eleonora Rizzi, Thomas Fleetwood, Giuliano Pinna, Greta Maria Giacomini
    29-08-2024
    https://doi.org/10.4081/itjm.2024.1770
    622
    PDF: 452
    HTML: 293
  • Safety and efficacy of thromboprophylaxis with fondaparinux in elderly acutely ill medical patients with renal impairment: a retrospective single center study

    Federico Silvestri, Samantha Pasca, Marco Zaramella, Antonella Labombarda, Andrea Barbi, Mauro Desideri, Paolo Guidi, Adolfo Rogato, Matteo Bergamo, Giovanni Barillari
    287-292
    17-12-2013
    https://doi.org/10.4081/itjm.2013.287
    1569
    PDF: 937
    HTML: 294
  • Adult sickle cell disease and SARS-CoV-2: an increasingly common comorbidity for a rare disease

    Michaela Boggan, Christopher L. Edwards, Jordan Meek, Mary Wood, W. Jeff Bryson, John J. Sollers, Debra O. Parker, Camela S. Barker, Jessica Miller, Brianna Downey, Asha Lockett, Jazmin Rosales, Courtney Munroe, Jr., Noa Wax, Sharena Scott
    27-08-2024
    https://doi.org/10.4081/itjm.2024.1701
    553
    PDF: 402
    SUPPLEMENTARY MATERIAL: 202
    HTML: 55
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Vol. 19 No. 2 (2025)
Minimally invasive versus median sternotomy for mechanical mitral valve replacement: a single-center comparative study of treatment outcomes...
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12 June 2025
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The role of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in assessing hypothyroidism Hashimoto’s thyroiditis
Ruqeya Murad et al.
10 June 2025
Vol. 19 No. 2 (2025)
A “cold” case of myxedema coma
Elisa Eletto et al.
15 May 2025
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