Multiple organ failure as onset of Mediterranean spotted fever: a review based on a case

Submitted: 16 July 2015
Accepted: 15 February 2016
Published: 30 September 2016
Abstract Views: 1180
PDF: 729
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Mediterranean spotted fever (MSF) is an infectious disease endemic in the southern regions of Italy, with an incidence of about 400 cases/year. The bacteria responsible of the disease is Rickettsia conorii, transmitted to humans by Rhipicephalus sanguineus, the common dog tick. The infection usually manifests with a characteristic symptomatologic triad: fever, exanthema and the so called tache noire, which is the typical eschar at the site of the tick bite. Immunoglobulin M (IgM) and IgG enzymelinked immunosorbent assay and the gold standard micro-immunofluorescent assay, allow serological diagnosis. We report the case of a man suffering from MSF, whose atypical presentation and false-negative diagnostic tests delayed consistently diagnosis and therapy. Afterwards we review the literature about this topic.

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Mansueto, P., Seidita, A., Bongiovì, A., Catalano, T., Pirrone, G., Cusimano, C., D’Alcamo, A., & Carroccio, A. (2016). Multiple organ failure as onset of Mediterranean spotted fever: a review based on a case. Italian Journal of Medicine, 10(3), 195–201. https://doi.org/10.4081/itjm.2016.625

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