Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management

  • Andrea Percivale Department of Surgery, Santa Corona Hospital, Pietra Ligure (SV), Italy.
  • Paola Gnerre | pgnerre@yahoo.it Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Giulio Damonte Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Sandra Buscaglia Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Mario Monachesi Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Lionello Parodi Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Rodolfo Tassara Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Gianluca Curletti Department of Surgery, University of Genova, Genova, Italy.
  • Giovanni Saccomani Department of Surgery, Santa Corona Hospital, Pietra Ligure (SV), Italy.

Abstract

Primary hyperparathyroidism (PHPT) is a clinical condition characterized by overactive parathyroid gland secretion of parathyroid hormone with concurrent alteration of the phosphocalcemic metabolism. We present a literature review on primary hyperparathyroidism addressing key on clinical presentation, causes, medical and surgical treatment at the best of our knowledge. Based on this review we confirm the role of serum calcium and serum level examination, as well as we define the definitive treatment for PHPT being parathyroidectomy. In case of contraindication for surgery, medical treatment can play a relevant role.

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Published
2015-12-15
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Section
Reviews
Keywords:
Primary hyperparathyroidism, parathyroidectomy, hypercalcemic status.
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How to Cite
Percivale, A., Gnerre, P., Damonte, G., Buscaglia, S., Monachesi, M., Parodi, L., Tassara, R., Curletti, G., & Saccomani, G. (2015). Primary hyperparathyroidism: epidemiology, clinical features, diagnostic tools and current management. Italian Journal of Medicine, 9(4), 330-345. https://doi.org/10.4081/itjm.2015.547

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