Hypocomplementemic urticarial vasculitis complicated with diffuse alveolar hemorrhage: a case report and review of literature

  • Paola Gnerre | pgnerre@yahoo.it Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Sandra Buscaglia Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Alessandro Cattana Department of Internal Medicine, San Paolo Hospital, Savona, Italy.
  • Andrea Pestarino Department of Dermatology, San Paolo Hospital, Savona, Italy.
  • Silvia Ardoino Department of Pathology, San Paolo Hospital, Savona, Italy.
  • Ezio Venturino Department of Pathology, San Paolo Hospital, Savona, Italy.
  • Lionello Parodi Department of Internal Medicine, San Paolo Hospital, Savona, Italy.

Abstract

Urticarial vasculitis is a small-vessel vasculitis characterized clinically by urticaria and microscopically by leukocytoclastic vasculitis. Hypocomplementemic urticarial vasculitis syndrome is a rare subtype of urticarial vasculitis with organ involvement and persistent, acquired hypocomplementemia. Pulmonary involvement, usually seen as diffuse alveolar damage, is an uncommon complication and a significant cause of morbidity and mortality. Here we present a rare case of hypocomplementemic urticarial vasculitis syndrome complicated by diffuse alveolar damage and describe the beneficial effect of cyclophosphamide-dexamethasone.

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Published
2014-03-17
Section
Case Reports
Keywords:
hypocomplementemic urticarial vasculitis, leukocytoclastic vasculitis, diffuse alveolar hemorrhage.
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How to Cite
Gnerre, P., Buscaglia, S., Cattana, A., Pestarino, A., Ardoino, S., Venturino, E., & Parodi, L. (2014). Hypocomplementemic urticarial vasculitis complicated with diffuse alveolar hemorrhage: a case report and review of literature. Italian Journal of Medicine, 8(1), 44-50. https://doi.org/10.4081/itjm.2014.155

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