P130 | Incidence of acute pancreatitis in Sicily (2004-2020). A population-based study

M. Rossi¹, R. Patti¹, M. Maringhini², V. Vassallo¹, A. Maringhini¹ | ¹ARNAS Civico Medicina 1, Palermo, ²ARNAS Civico Medicina 1, Palermo, Italy

Abstract

Premises and Purpose of the study: A recent meta-analysis demonstrated a rising incidence of acute pancreatitis (AP) in Western Countries. In this report we evaluated incidence trend of AP in a Sicilian population-based study to confirm this data.
Materials and Methods: We identified all hospital discharge records (HDR) of hospitalized Sicilian inhabitants (2004-2020). AP hospital admission and its relationship with age and gender, chronic pancreatitis (CP) and pancreatic cancer (PC) were calculated.
Results: We observed 50,649 hospital admission with AP (ICD-9CM Code 577.0). AP increased from 2,628 (2004) to 3,301 (2015) then decreased irregularly to 2,979 in 2019. In 2020 (COVID-19 pandemic), admissions were 2,395. All year’s admissions were not different for gender. Out of 50,649 hospital admission, we identified 39,501 patients. 8,254 of them (21%) had a diagnosis of CP (ICD-9CM Code 577.1). 2,213 CP (26.8%) had a previous hospitalization for AP. Out of 39,501 patients 37,288 (94%) had a single episode of AP hospital admission; 2213 (5,6%) had relapse of AP or new diagnosis of CP. In 765 patients with AP had a final diagnosis of PC (ICD-9CM code 140 X-239 X: in 120 PC was diagnosed before AP, in 151 PC and AP were coincidental, in 494 PC was diagnosed later.
Conclusions: We observed an increase incidence in AP hospital admission (2004-2019) and a decreased incidence during COVID-19 pandemic. CP and PC are frequently diagnosed after a previous AP hospital admission, so we suggest a clinical surveillance for CP and PC after AP hospitalization, likely for idiopathic AP