P66 | A not so clear pancreatitis
V. Ferrari, C. Mazzanti | Ospedale S. Andrea, Università di Roma La Sapienza, Roma, Italy
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Premises: Autoimmune IgG4 pancreatitis (AIP) is a fibro-inflammatory form characterized by radiographically indistinguishable expansive lesions from pancreatic cancer with lymphoplasmocytic infiltration of positive IgG4 plasma cells and increased serum IgG4 concentration. It is manifested by obstructive jaundice, increased cholestasis indices, abdominal pain, diarrhea. It has a systemic involvement especially of the salivary and lacrimal glands but can potentially affect any organ.
Description of the Case report: We report the case of a patient who came to the hospital for jaundice, diarrhea and abdominal pain. In history systemic hypertension, vitiligo and psoriasis. At examinations total bilirubin 19.7 mg/dl of which 14 direct. At the NMR expansive lesion of the head of the pancreas, peripancreatic edema and sausage-shaped were seen. Endoscopic-Ultrasonography showed fibrosis. Diagnosis was confirmed with histology and IgG4 dosage. He immediately started cortisone with improvement of the clinical picture. As a complication he developed diabetes mellitus.
Conclusions: In conclusion, AIP is a rare but insidious disease that should be considered whenever there is a suspicion of an expansive lesion of the pancreas or bile ducts.
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