https://doi.org/10.4081/itjm.2025.2154
CO03 | The vaccination of chronic patients: a systematic and evidence-based approach
P. Amoriello Lamberti, S.M. Gherardi, G. Adamo, C. Vazzoler, G. Lobrano, N.R. Mallamace, C. Morvile, F. Trani, V. Mazzocato, G. Colaiocco | UOC Coordinamento delle Attività Vaccinali ASL Roma2, Roma, Italy
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Published: 25 August 2025
Premises and Purpose of the study: According to the WHO, vaccinations prevent approximately 3.5-5 million deaths/year. The importance of vaccinations is even more relevant in frail subjects (elderly, multi-comorbid patients with chronic diseases, immunocompromised) who are at greater risk of infections and related complications. However, vaccination coverage for these patients is still very low. One of the reasons is the absence of operational tools that support healthcare professionals in promoting vaccinations. For this reason, a document that summarizes the main indications has been developed.
Materials and Methods: Starting from the PNPV in force, we analyzed the guidelines of the main scientific societies and the documents of the CDC and the WHO, implementing the data with a systematic literature review. Four “immunization profiles” were defined, providing a comprehensive overview for homogeneous vaccination strategies.
Results: The Clinical Vaccinology Notebook has been developed. It is divided in two parts: the Clinical Vaccinology Notes, which provide basic informations to promote vaccinations, and the Operational Schemes for the practical management.
Conclusions: The Clinical Vaccinology Notebook aims to be a useful and innovative tool that highlights the importance of providing patient centered care and facilitates the management of vaccinations in chronic patients, optimizing and increasing the awareness of healthcare professionals and patients in different settings with a continuous up-to-date according to the main guidelines and evidences.
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